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A systematic review of BNP as a predictor of prognosis in persons with coronary artery disease

This systematic review was conducted to examine whether B-type natriuretic peptide (BNP) can predict mortality and other cardiac endpoints in persons diagnosed with coronary artery disease (CAD). Databases were searched from 1989 to February 2005 for primary studies that measured BNP for the purpose... Full description

Journal Title: Clinical Biochemistry 2008, Vol.41(4), pp.260-265
Main Author: Oremus, Mark
Other Authors: Raina, Parminder S , Santaguida, Pasqualina , Balion, Cynthia M , Mcqueen, Matthew J , Mckelvie, Robert , Worster, Andrew , Booker, Lynda , Hill, Stephen A
Format: Electronic Article Electronic Article
Language: English
Subjects:
Bnp
Bnp
ID: ISSN: 0009-9120 ; E-ISSN: 1873-2933 ; DOI: 10.1016/j.clinbiochem.2007.09.011
Link: http://dx.doi.org/10.1016/j.clinbiochem.2007.09.011
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recordid: elsevier_sdoi_10_1016_j_clinbiochem_2007_09_011
title: A systematic review of BNP as a predictor of prognosis in persons with coronary artery disease
format: Article
creator:
  • Oremus, Mark
  • Raina, Parminder S
  • Santaguida, Pasqualina
  • Balion, Cynthia M
  • Mcqueen, Matthew J
  • Mckelvie, Robert
  • Worster, Andrew
  • Booker, Lynda
  • Hill, Stephen A
subjects:
  • Bnp
  • B-Type Natriuretic Peptide
  • Coronary Artery Disease
  • Prognosis
  • Bnp
  • B-Type Natriuretic Peptide
  • Coronary Artery Disease
  • Prognosis
  • Medicine
  • Chemistry
ispartof: Clinical Biochemistry, 2008, Vol.41(4), pp.260-265
description: This systematic review was conducted to examine whether B-type natriuretic peptide (BNP) can predict mortality and other cardiac endpoints in persons diagnosed with coronary artery disease (CAD). Databases were searched from 1989 to February 2005 for primary studies that measured BNP for the purpose of diagnosis, prognosis, and monitoring treatment. In 18 studies, concentrations of BNP were found to have consistent positive associations with poorer prognoses for persons with CAD. The overall range of effect (95% confidence interval) was 2.31 to 5.02, measured via a random effects meta-analysis on studies reporting an odds ratio. Prognostic ability was similar for mortality and non-fatal outcomes. Ranges of estimated measures of effect (i.e., odds ratio, relative risk, hazard ratio) were concentrated between 1.33 to 2.94 for mortality and 1.01 to 3.03 for non-fatal outcomes. Further research is needed to assess whether prognostic...
language: eng
source:
identifier: ISSN: 0009-9120 ; E-ISSN: 1873-2933 ; DOI: 10.1016/j.clinbiochem.2007.09.011
fulltext: fulltext
issn:
  • 0009-9120
  • 00099120
  • 1873-2933
  • 18732933
url: Link


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titleA systematic review of BNP as a predictor of prognosis in persons with coronary artery disease
creatorOremus, Mark ; Raina, Parminder S ; Santaguida, Pasqualina ; Balion, Cynthia M ; Mcqueen, Matthew J ; Mckelvie, Robert ; Worster, Andrew ; Booker, Lynda ; Hill, Stephen A
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descriptionThis systematic review was conducted to examine whether B-type natriuretic peptide (BNP) can predict mortality and other cardiac endpoints in persons diagnosed with coronary artery disease (CAD). Databases were searched from 1989 to February 2005 for primary studies that measured BNP for the purpose of diagnosis, prognosis, and monitoring treatment. In 18 studies, concentrations of BNP were found to have consistent positive associations with poorer prognoses for persons with CAD. The overall range of effect (95% confidence interval) was 2.31 to 5.02, measured via a random effects meta-analysis on studies reporting an odds ratio. Prognostic ability was similar for mortality and non-fatal outcomes. Ranges of estimated measures of effect (i.e., odds ratio, relative risk, hazard ratio) were concentrated between 1.33 to 2.94 for mortality and 1.01 to 3.03 for non-fatal outcomes. Further research is needed to assess whether prognostic...
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