schliessen

Filtern

 

Bibliotheken

Controlled release and antibacterial activity of antibiotic-loaded electrospun halloysite/poly(lactic-co-glycolic acid) composite nanofibers

Fabrication of nanofiber-based drug delivery system with controlled release property is of general interest in biomedical sciences. In this study, we prepared an antibiotic drug tetracycline hydrochloride (TCH)-loaded halloysite nanotubes/poly(lactic-co-glycolic acid) composite nanofibers (TCH/HNTs/... Full description

Journal Title: Colloids and Surfaces B: Biointerfaces 01 October 2013, Vol.110, pp.148-155
Main Author: Qi, Ruiling
Other Authors: Guo, Rui , Zheng, Fuyin , Liu, Hui , Yu, Jianyong , Shi, Xiangyang
Format: Electronic Article Electronic Article
Language: English
Subjects:
ID: ISSN: 0927-7765 ; E-ISSN: 1873-4367 ; DOI: 10.1016/j.colsurfb.2013.04.036
Link: https://www.sciencedirect.com/science/article/pii/S0927776513002944
Zum Text:
SendSend as email Add to Book BagAdd to Book Bag
Staff View
recordid: elsevier_sdoi_10_1016_j_colsurfb_2013_04_036
title: Controlled release and antibacterial activity of antibiotic-loaded electrospun halloysite/poly(lactic-co-glycolic acid) composite nanofibers
format: Article
creator:
  • Qi, Ruiling
  • Guo, Rui
  • Zheng, Fuyin
  • Liu, Hui
  • Yu, Jianyong
  • Shi, Xiangyang
subjects:
  • Electrospun Nanofibers
  • Halloysite Nanotubes
  • Tetracycline Hydrochloride
  • Controlled Release
  • Antibacterial Activity
  • Engineering
  • Chemistry
  • Anatomy & Physiology
ispartof: Colloids and Surfaces B: Biointerfaces, 01 October 2013, Vol.110, pp.148-155
description: Fabrication of nanofiber-based drug delivery system with controlled release property is of general interest in biomedical sciences. In this study, we prepared an antibiotic drug tetracycline hydrochloride (TCH)-loaded halloysite nanotubes/poly(lactic-co-glycolic acid) composite nanofibers (TCH/HNTs/PLGA), and evaluated the drug release and antibacterial activity of this drug delivery system. The structure, morphology, and mechanical properties of the formed electrospun TCH/HNTs/PLGA composite nanofibrous mats were characterized using scanning electron microscopy (SEM), Fourier transform infrared spectroscopy, and tensile testing. We show that the incorporation of TCH-loaded HNTs within the PLGA nanofibers is able to improve the tensile strength and maintain the three-dimensional structure of the nanofibrous mats. viability assay and SEM morphology observation of mouse fibroblast cells cultured onto the fibrous scaffolds demonstrate that the developed TCH/HNTs/PLGA...
language: eng
source:
identifier: ISSN: 0927-7765 ; E-ISSN: 1873-4367 ; DOI: 10.1016/j.colsurfb.2013.04.036
fulltext: fulltext
issn:
  • 0927-7765
  • 09277765
  • 1873-4367
  • 18734367
url: Link


@attributes
ID1782311702
RANK0.07
NO1
SEARCH_ENGINEprimo_central_multiple_fe
SEARCH_ENGINE_TYPEPrimo Central Search Engine
LOCALfalse
PrimoNMBib
record
control
sourcerecordiddoi_10_1016_j_colsurfb_2013_04_036
sourceidelsevier_s
recordidTN_elsevier_sdoi_10_1016_j_colsurfb_2013_04_036
sourcesystemPC
dbid
0--K
1--M
2.~1
31B1
41~.
5457
64G.
77-5
88P~
99JM
109JN
11AAEDT
12AAEPC
13AAKOC
14AAOAW
15AAQFI
16AARLI
17ABGSF
18ABNUV
19ABXRA
20ABYKQ
21ACDAQ
22ACFVG
23ACRLP
24ADECG
25ADEWK
26ADUVX
27AEHWI
28AEKER
29AEZYN
30AFKWA
31AFTJW
32AFXIZ
33AGHFR
34AGUBO
35AGYEJ
36AHPOS
37AIKHN
38AITUG
39AIVDX
40AJBFU
41AJOXV
42AJSZI
43AMFUW
44BLXMC
45DOVZS
46ENUVR
47EO8
48EO9
49EP2
50EP3
51FDB
52FIRID
53FLBIZ
54FNPLU
55G-Q
56GBLVA
57J1W
58KOM
59MAGPM
60OAUVE
61OGIMB
62P-8
63P-9
64PC.
65Q38
66RPZ
67SDF
68SDG
69SDP
70SES
71SPC
72SSG
73SSK
74SSM
75SSQ
76SSU
77SSZ
78T5K
79~G-
pqid1642610606
display
typearticle
titleControlled release and antibacterial activity of antibiotic-loaded electrospun halloysite/poly(lactic-co-glycolic acid) composite nanofibers
creatorQi, Ruiling ; Guo, Rui ; Zheng, Fuyin ; Liu, Hui ; Yu, Jianyong ; Shi, Xiangyang
ispartofColloids and Surfaces B: Biointerfaces, 01 October 2013, Vol.110, pp.148-155
identifier
subjectElectrospun Nanofibers ; Halloysite Nanotubes ; Tetracycline Hydrochloride ; Controlled Release ; Antibacterial Activity ; Engineering ; Chemistry ; Anatomy & Physiology
descriptionFabrication of nanofiber-based drug delivery system with controlled release property is of general interest in biomedical sciences. In this study, we prepared an antibiotic drug tetracycline hydrochloride (TCH)-loaded halloysite nanotubes/poly(lactic-co-glycolic acid) composite nanofibers (TCH/HNTs/PLGA), and evaluated the drug release and antibacterial activity of this drug delivery system. The structure, morphology, and mechanical properties of the formed electrospun TCH/HNTs/PLGA composite nanofibrous mats were characterized using scanning electron microscopy (SEM), Fourier transform infrared spectroscopy, and tensile testing. We show that the incorporation of TCH-loaded HNTs within the PLGA nanofibers is able to improve the tensile strength and maintain the three-dimensional structure of the nanofibrous mats. viability assay and SEM morphology observation of mouse fibroblast cells cultured onto the fibrous scaffolds demonstrate that the developed TCH/HNTs/PLGA...
languageeng
source
version6
lds50peer_reviewed
links
openurl$$Topenurl_article
openurlfulltext$$Topenurlfull_article
backlink$$Uhttps://www.sciencedirect.com/science/article/pii/S0927776513002944$$EView_record_in_ScienceDirect_(Access_to_full_text_may_be_restricted)
search
creatorcontrib
0Qi, Ruiling
1Guo, Rui
2Zheng, Fuyin
3Liu, Hui
4Yu, Jianyong
5Shi, Xiangyang
titleControlled release and antibacterial activity of antibiotic-loaded electrospun halloysite/poly(lactic-co-glycolic acid) composite nanofibers
description

Fabrication of nanofiber-based drug delivery system with controlled release property is of general interest in biomedical sciences. In this study, we prepared an antibiotic drug tetracycline hydrochloride (TCH)-loaded halloysite nanotubes/poly(lactic-co-glycolic acid) composite nanofibers (TCH/HNTs/PLGA), and evaluated the drug release and antibacterial activity of this drug delivery system. The structure, morphology, and mechanical properties of the formed electrospun TCH/HNTs/PLGA composite nanofibrous mats were characterized using scanning electron microscopy (SEM), Fourier transform infrared spectroscopy, and tensile testing. We show that the incorporation of TCH-loaded HNTs within the PLGA nanofibers is able to improve the tensile strength and maintain the three-dimensional structure of the nanofibrous mats.

viability assay and SEM morphology observation of mouse fibroblast cells cultured onto the fibrous scaffolds demonstrate that the developed TCH/HNTs/PLGA...

subject
0Electrospun Nanofibers
1Halloysite Nanotubes
2Tetracycline Hydrochloride
3Controlled Release
4Antibacterial Activity
5Engineering
6Chemistry
7Anatomy & Physiology
general
0English
1Elsevier B.V
210.1016/j.colsurfb.2013.04.036
3ScienceDirect (Elsevier)
4ScienceDirect Journals (Elsevier)
sourceidelsevier_s
recordidelsevier_sdoi_10_1016_j_colsurfb_2013_04_036
issn
00927-7765
109277765
21873-4367
318734367
rsrctypearticle
creationdate2013
addtitleColloids and Surfaces B: Biointerfaces
searchscope
0elsevier_full
1elsevier2
scope
0elsevier_full
1elsevier2
lsr44$$EView_record_in_ScienceDirect_(Access_to_full_text_may_be_restricted)
tmp01ScienceDirect Journals (Elsevier)
tmp02
0--K
1--M
2.~1
31B1
41~.
5457
64G.
77-5
88P~
99JM
109JN
11AAEDT
12AAEPC
13AAKOC
14AAOAW
15AAQFI
16AARLI
17ABGSF
18ABNUV
19ABXRA
20ABYKQ
21ACDAQ
22ACFVG
23ACRLP
24ADECG
25ADEWK
26ADUVX
27AEHWI
28AEKER
29AEZYN
30AFKWA
31AFTJW
32AFXIZ
33AGHFR
34AGUBO
35AGYEJ
36AHPOS
37AIKHN
38AITUG
39AIVDX
40AJBFU
41AJOXV
42AJSZI
43AMFUW
44BLXMC
45DOVZS
46ENUVR
47EO8
48EO9
49EP2
50EP3
51FDB
52FIRID
53FLBIZ
54FNPLU
55G-Q
56GBLVA
57J1W
58KOM
59MAGPM
60OAUVE
61OGIMB
62P-8
63P-9
64PC.
65Q38
66RPZ
67SDF
68SDG
69SDP
70SES
71SPC
72SSG
73SSK
74SSM
75SSQ
76SSU
77SSZ
78T5K
79~G-
startdate20131001
enddate20131001
lsr40Colloids and Surfaces B: Biointerfaces, 01 October 2013, Vol.110, pp.148-155
doi10.1016/j.colsurfb.2013.04.036
citationpf 148 pt 155 vol 110
lsr30VSR-Enriched:[pqid]
sort
titleControlled release and antibacterial activity of antibiotic-loaded electrospun halloysite/poly(lactic-co-glycolic acid) composite nanofibers
authorQi, Ruiling ; Guo, Rui ; Zheng, Fuyin ; Liu, Hui ; Yu, Jianyong ; Shi, Xiangyang
creationdate20131001
lso0120131001
facets
frbrgroupid4719544541870254966
frbrtype5
newrecords20190904
languageeng
topic
0Electrospun Nanofibers
1Halloysite Nanotubes
2Tetracycline Hydrochloride
3Controlled Release
4Antibacterial Activity
5Engineering
6Chemistry
7Anatomy & Physiology
collectionScienceDirect (Elsevier)
prefilterarticles
rsrctypearticles
creatorcontrib
0Qi, Ruiling
1Guo, Rui
2Zheng, Fuyin
3Liu, Hui
4Yu, Jianyong
5Shi, Xiangyang
jtitleColloids and Surfaces B: Biointerfaces
creationdate2013
toplevelpeer_reviewed
delivery
delcategoryRemote Search Resource
fulltextfulltext
addata
aulast
0Qi
1Guo
2Zheng
3Liu
4Yu
5Shi
aufirst
0Ruiling
1Rui
2Fuyin
3Hui
4Jianyong
5Xiangyang
auinitR
auinit1R
au
0Qi, Ruiling
1Guo, Rui
2Zheng, Fuyin
3Liu, Hui
4Yu, Jianyong
5Shi, Xiangyang
atitleControlled release and antibacterial activity of antibiotic-loaded electrospun halloysite/poly(lactic-co-glycolic acid) composite nanofibers
jtitleColloids and Surfaces B: Biointerfaces
risdate20131001
volume110
spage148
epage155
pages148-155
issn0927-7765
eissn1873-4367
formatjournal
genrearticle
ristypeJOUR
abstract

Fabrication of nanofiber-based drug delivery system with controlled release property is of general interest in biomedical sciences. In this study, we prepared an antibiotic drug tetracycline hydrochloride (TCH)-loaded halloysite nanotubes/poly(lactic-co-glycolic acid) composite nanofibers (TCH/HNTs/PLGA), and evaluated the drug release and antibacterial activity of this drug delivery system. The structure, morphology, and mechanical properties of the formed electrospun TCH/HNTs/PLGA composite nanofibrous mats were characterized using scanning electron microscopy (SEM), Fourier transform infrared spectroscopy, and tensile testing. We show that the incorporation of TCH-loaded HNTs within the PLGA nanofibers is able to improve the tensile strength and maintain the three-dimensional structure of the nanofibrous mats.

viability assay and SEM morphology observation of mouse fibroblast cells cultured onto the fibrous scaffolds demonstrate that the developed TCH/HNTs/PLGA...

pubElsevier B.V
doi10.1016/j.colsurfb.2013.04.036
lad01Colloids and Surfaces B: Biointerfaces
date2013-10-01