schliessen

Filtern

 

Bibliotheken

Enhanced topical delivery of hyaluronic acid encapsulated in liposomes: A surface-dependent phenomenon

Liposomes containing HA formed SLBs onto the human skin were HA is mainly liberated in the epidermis. •Hyaluronic acid encapsulated in liposomes shows increased bioavailability for topical application.•Penetration enhancers incorporated modify the permeation of HA in cellulose and human skin.•Struct... Full description

Journal Title: Colloids and Surfaces B: Biointerfaces 01 October 2015, Vol.134, pp.31-39
Main Author: Vázquez-González, Martha L
Other Authors: Calpena, Ana C , Domènech, Òscar , Montero, M. Teresa , Borrell, Jordi H
Format: Electronic Article Electronic Article
Language: English
Subjects:
Afm
Afm
ID: ISSN: 0927-7765 ; E-ISSN: 1873-4367 ; DOI: 10.1016/j.colsurfb.2015.06.029
Link: http://dx.doi.org/10.1016/j.colsurfb.2015.06.029
Zum Text:
SendSend as email Add to Book BagAdd to Book Bag
Staff View
recordid: elsevier_sdoi_10_1016_j_colsurfb_2015_06_029
title: Enhanced topical delivery of hyaluronic acid encapsulated in liposomes: A surface-dependent phenomenon
format: Article
creator:
  • Vázquez-González, Martha L
  • Calpena, Ana C
  • Domènech, Òscar
  • Montero, M. Teresa
  • Borrell, Jordi H
subjects:
  • Hyaluronic Acid
  • Liposomes
  • Skin
  • Penetration Enhancers
  • Drug Delivery
  • Afm
  • Force Volume
  • Hyaluronic Acid
  • Liposomes
  • Skin
  • Penetration Enhancers
  • Drug Delivery
  • Afm
  • Force Volume
  • Engineering
  • Chemistry
  • Anatomy & Physiology
ispartof: Colloids and Surfaces B: Biointerfaces, 01 October 2015, Vol.134, pp.31-39
description: Liposomes containing HA formed SLBs onto the human skin were HA is mainly liberated in the epidermis. •Hyaluronic acid encapsulated in liposomes shows increased bioavailability for topical application.•Penetration enhancers incorporated modify the permeation of HA in cellulose and human skin.•Structures onto surfaces were observed by AFM.•Adhesion forces were measured by AFM-Force volume mode.•Multilayer lipid structures and permeation process seem to be related. In the present study, we investigated the release and permeation of hyaluronic acid (HA) encapsulated in liposomes when deposited onto two surfaces: cellulose, a model widely used for investigating transport of drugs; and human skin, a natural biointerface used for transdermal drug delivery. We prepared and characterised liposomes loaded with HA and liposomes incorporating two penetration enhancers (PEs): the non-ionic surfactant Tween® 80, and Transcutol® P, a solubilising agent...
language: eng
source:
identifier: ISSN: 0927-7765 ; E-ISSN: 1873-4367 ; DOI: 10.1016/j.colsurfb.2015.06.029
fulltext: fulltext
issn:
  • 0927-7765
  • 09277765
  • 1873-4367
  • 18734367
url: Link


@attributes
ID1225395048
RANK0.07
NO1
SEARCH_ENGINEprimo_central_multiple_fe
SEARCH_ENGINE_TYPEPrimo Central Search Engine
LOCALfalse
PrimoNMBib
record
control
sourcerecordiddoi_10_1016_j_colsurfb_2015_06_029
sourceidelsevier_s
recordidTN_elsevier_sdoi_10_1016_j_colsurfb_2015_06_029
sourcesystemPC
dbid
0--K
1--M
2.~1
31B1
41~.
5457
64G.
77-5
88P~
99JM
109JN
11AAEDT
12AAEPC
13AAKOC
14AAOAW
15AAQFI
16AARLI
17ABGSF
18ABNUV
19ABXRA
20ABYKQ
21ACDAQ
22ACFVG
23ACRLP
24ADALY
25ADECG
26ADEWK
27ADUVX
28AEHWI
29AEKER
30AEZYN
31AFKWA
32AFTJW
33AFXIZ
34AGHFR
35AGUBO
36AGYEJ
37AHPOS
38AIKHN
39AITUG
40AIVDX
41AJBFU
42AJOXV
43AJSZI
44AMFUW
45BLXMC
46DOVZS
47ENUVR
48EO8
49EO9
50EP2
51EP3
52FDB
53FIRID
54FLBIZ
55FNPLU
56G-Q
57GBLVA
58J1W
59KOM
60MAGPM
61OAUVE
62OGIMB
63P-8
64P-9
65PC.
66Q38
67RPZ
68SDF
69SDG
70SDP
71SES
72SPC
73SSG
74SSK
75SSM
76SSQ
77SSU
78SSZ
79T5K
80~G-
pqid1777993340
display
typearticle
titleEnhanced topical delivery of hyaluronic acid encapsulated in liposomes: A surface-dependent phenomenon
creatorVázquez-González, Martha L ; Calpena, Ana C ; Domènech, Òscar ; Montero, M. Teresa ; Borrell, Jordi H
ispartofColloids and Surfaces B: Biointerfaces, 01 October 2015, Vol.134, pp.31-39
identifier
subjectHyaluronic Acid ; Liposomes ; Skin ; Penetration Enhancers ; Drug Delivery ; Afm ; Force Volume ; Hyaluronic Acid ; Liposomes ; Skin ; Penetration Enhancers ; Drug Delivery ; Afm ; Force Volume ; Engineering ; Chemistry ; Anatomy & Physiology
descriptionLiposomes containing HA formed SLBs onto the human skin were HA is mainly liberated in the epidermis. •Hyaluronic acid encapsulated in liposomes shows increased bioavailability for topical application.•Penetration enhancers incorporated modify the permeation of HA in cellulose and human skin.•Structures onto surfaces were observed by AFM.•Adhesion forces were measured by AFM-Force volume mode.•Multilayer lipid structures and permeation process seem to be related. In the present study, we investigated the release and permeation of hyaluronic acid (HA) encapsulated in liposomes when deposited onto two surfaces: cellulose, a model widely used for investigating transport of drugs; and human skin, a natural biointerface used for transdermal drug delivery. We prepared and characterised liposomes loaded with HA and liposomes incorporating two penetration enhancers (PEs): the non-ionic surfactant Tween® 80, and Transcutol® P, a solubilising agent...
languageeng
source
version6
lds50peer_reviewed
links
openurl$$Topenurl_article
openurlfulltext$$Topenurlfull_article
backlink$$Uhttp://dx.doi.org/10.1016/j.colsurfb.2015.06.029$$EView_record_in_ScienceDirect_(Access_to_full_text_may_be_restricted)
search
creatorcontrib
0Vázquez-González, Martha L
1Calpena, Ana C
2Domènech, Òscar
3Montero, M. Teresa
4Borrell, Jordi H
titleEnhanced topical delivery of hyaluronic acid encapsulated in liposomes: A surface-dependent phenomenon
description

Liposomes containing HA formed SLBs onto the human skin were HA is mainly liberated in the epidermis.

•Hyaluronic acid encapsulated in liposomes shows increased bioavailability for topical application.•Penetration enhancers incorporated modify the permeation of HA in cellulose and human skin.•Structures onto surfaces were observed by AFM.•Adhesion forces were measured by AFM-Force volume mode.•Multilayer lipid structures and permeation process seem to be related.

In the present study, we investigated the release and permeation of hyaluronic acid (HA) encapsulated in liposomes when deposited onto two surfaces: cellulose, a model widely used for investigating transport of drugs; and human skin, a natural biointerface used for transdermal drug delivery. We prepared and characterised liposomes loaded with HA and liposomes incorporating two penetration enhancers (PEs): the non-ionic surfactant Tween® 80, and Transcutol® P, a solubilising agent...

subject
0Hyaluronic Acid
1Liposomes
2Skin
3Penetration Enhancers
4Drug Delivery
5Afm
6Force Volume
7Engineering
8Chemistry
9Anatomy & Physiology
general
0English
1Elsevier B.V
210.1016/j.colsurfb.2015.06.029
3ScienceDirect (Elsevier)
4ScienceDirect Journals (Elsevier)
sourceidelsevier_s
recordidelsevier_sdoi_10_1016_j_colsurfb_2015_06_029
issn
00927-7765
109277765
21873-4367
318734367
rsrctypearticle
creationdate2015
addtitleColloids and Surfaces B: Biointerfaces
searchscope
0elsevier_full
1elsevier2
scope
0elsevier_full
1elsevier2
lsr44$$EView_record_in_ScienceDirect_(Access_to_full_text_may_be_restricted)
tmp01ScienceDirect Journals (Elsevier)
tmp02
0--K
1--M
2.~1
31B1
41~.
5457
64G.
77-5
88P~
99JM
109JN
11AAEDT
12AAEPC
13AAKOC
14AAOAW
15AAQFI
16AARLI
17ABGSF
18ABNUV
19ABXRA
20ABYKQ
21ACDAQ
22ACFVG
23ACRLP
24ADALY
25ADECG
26ADEWK
27ADUVX
28AEHWI
29AEKER
30AEZYN
31AFKWA
32AFTJW
33AFXIZ
34AGHFR
35AGUBO
36AGYEJ
37AHPOS
38AIKHN
39AITUG
40AIVDX
41AJBFU
42AJOXV
43AJSZI
44AMFUW
45BLXMC
46DOVZS
47ENUVR
48EO8
49EO9
50EP2
51EP3
52FDB
53FIRID
54FLBIZ
55FNPLU
56G-Q
57GBLVA
58J1W
59KOM
60MAGPM
61OAUVE
62OGIMB
63P-8
64P-9
65PC.
66Q38
67RPZ
68SDF
69SDG
70SDP
71SES
72SPC
73SSG
74SSK
75SSM
76SSQ
77SSU
78SSZ
79T5K
80~G-
startdate20151001
enddate20151001
lsr40Colloids and Surfaces B: Biointerfaces, 01 October 2015, Vol.134, pp.31-39
doi10.1016/j.colsurfb.2015.06.029
citationpf 31 pt 39 vol 134
lsr30VSR-Enriched:[pqid]
sort
titleEnhanced topical delivery of hyaluronic acid encapsulated in liposomes: A surface-dependent phenomenon
authorVázquez-González, Martha L ; Calpena, Ana C ; Domènech, Òscar ; Montero, M. Teresa ; Borrell, Jordi H
creationdate20151001
lso0120151001
facets
frbrgroupid2463994206817224988
frbrtype5
newrecords20190904
languageeng
topic
0Hyaluronic Acid
1Liposomes
2Skin
3Penetration Enhancers
4Drug Delivery
5Afm
6Force Volume
7Engineering
8Chemistry
9Anatomy & Physiology
collectionScienceDirect (Elsevier)
prefilterarticles
rsrctypearticles
creatorcontrib
0Vázquez-González, Martha L
1Calpena, Ana C
2Domènech, Òscar
3Montero, M. Teresa
4Borrell, Jordi H
jtitleColloids and Surfaces B: Biointerfaces
creationdate2015
toplevelpeer_reviewed
delivery
delcategoryRemote Search Resource
fulltextfulltext
addata
aulast
0Vázquez-González
1Calpena
2Domènech
3Montero
4Borrell
aufirst
0Martha L
1Ana C
2Òscar
3M. Teresa
4Jordi H
auinitM
auinit1M
au
0Vázquez-González, Martha L
1Calpena, Ana C
2Domènech, Òscar
3Montero, M. Teresa
4Borrell, Jordi H
atitleEnhanced topical delivery of hyaluronic acid encapsulated in liposomes: A surface-dependent phenomenon
jtitleColloids and Surfaces B: Biointerfaces
risdate20151001
volume134
spage31
epage39
pages31-39
issn0927-7765
eissn1873-4367
formatjournal
genrearticle
ristypeJOUR
abstract

Liposomes containing HA formed SLBs onto the human skin were HA is mainly liberated in the epidermis.

•Hyaluronic acid encapsulated in liposomes shows increased bioavailability for topical application.•Penetration enhancers incorporated modify the permeation of HA in cellulose and human skin.•Structures onto surfaces were observed by AFM.•Adhesion forces were measured by AFM-Force volume mode.•Multilayer lipid structures and permeation process seem to be related.

In the present study, we investigated the release and permeation of hyaluronic acid (HA) encapsulated in liposomes when deposited onto two surfaces: cellulose, a model widely used for investigating transport of drugs; and human skin, a natural biointerface used for transdermal drug delivery. We prepared and characterised liposomes loaded with HA and liposomes incorporating two penetration enhancers (PEs): the non-ionic surfactant Tween® 80, and Transcutol® P, a solubilising agent...

pubElsevier B.V
doi10.1016/j.colsurfb.2015.06.029
lad01Colloids and Surfaces B: Biointerfaces
date2015-10-01