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GW25-e0820 Apoptosis of THP-1 macrophage-derived foam cells induced by 5-aminolevulinic acid-mediated sonodynamic therapy is mitochondria-caspase pathway predominant despite the participation of endoplasmic reticulum stress

Pretreated with ROS inhibitor N-acetylcysteine (NAC), pan-caspase inhibitor Z-VAD-FMK and ER stress inhibitor 4-phenylbutyrate (4-PBA), expressions of mitochondria apoptosis associated proteins cytochromc c, cleaved caspase3, cleaved caspase9, Bcl-2, BAX and ER stress associated protein C/EBP-homolo... Full description

Journal Title: Journal of the American College of Cardiology 21 October 2014, Vol.64(16), pp.C57-C57
Main Author: Huan, Wang
Other Authors: Tian, Ye
Format: Electronic Article Electronic Article
Language: English
Subjects:
ID: ISSN: 0735-1097 ; E-ISSN: 1558-3597 ; DOI: 10.1016/j.jacc.2014.06.275
Link: https://www.sciencedirect.com/science/article/pii/S0735109714031702
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recordid: elsevier_sdoi_10_1016_j_jacc_2014_06_275
title: GW25-e0820 Apoptosis of THP-1 macrophage-derived foam cells induced by 5-aminolevulinic acid-mediated sonodynamic therapy is mitochondria-caspase pathway predominant despite the participation of endoplasmic reticulum stress
format: Article
creator:
  • Huan, Wang
  • Tian, Ye
subjects:
  • Medicine
ispartof: Journal of the American College of Cardiology, 21 October 2014, Vol.64(16), pp.C57-C57
description: Pretreated with ROS inhibitor N-acetylcysteine (NAC), pan-caspase inhibitor Z-VAD-FMK and ER stress inhibitor 4-phenylbutyrate (4-PBA), expressions of mitochondria apoptosis associated proteins cytochromc c, cleaved caspase3, cleaved caspase9, Bcl-2, BAX and ER stress associated protein C/EBP-homologous protein (CHOP) in FC after ALA-SDT were detected by Western blotting.
language: eng
source:
identifier: ISSN: 0735-1097 ; E-ISSN: 1558-3597 ; DOI: 10.1016/j.jacc.2014.06.275
fulltext: fulltext
issn:
  • 0735-1097
  • 07351097
  • 1558-3597
  • 15583597
url: Link


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descriptionPretreated with ROS inhibitor N-acetylcysteine (NAC), pan-caspase inhibitor Z-VAD-FMK and ER stress inhibitor 4-phenylbutyrate (4-PBA), expressions of mitochondria apoptosis associated proteins cytochromc c, cleaved caspase3, cleaved caspase9, Bcl-2, BAX and ER stress associated protein C/EBP-homologous protein (CHOP) in FC after ALA-SDT were detected by Western blotting.
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