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A Tale of Serendipity, Ingenuity, and Chance

The tubing consistently coils up comfortably in the right atrium (RA).Outside-the-Box Intuition Some weekends later, pondering Danzig’s frustration as he sits on Santa Monica beach watching sailboats, Jeremy has a Newton-apple flash of inspiration: a catheter equipped with sheets and sails could pas... Full description

Journal Title: Journal of the American College of Cardiology 09 July 2019, Vol.74(1), pp.100-103
Main Author: Forrester, James S
Format: Electronic Article Electronic Article
Language: English
Subjects:
ID: ISSN: 0735-1097 ; E-ISSN: 1558-3597 ; DOI: 10.1016/j.jacc.2019.04.050
Link: https://www.sciencedirect.com/science/article/pii/S0735109719351502
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recordid: elsevier_sdoi_10_1016_j_jacc_2019_04_050
title: A Tale of Serendipity, Ingenuity, and Chance
format: Article
creator:
  • Forrester, James S
subjects:
  • Forrester Classification
  • Hemodynamic Subsets
  • Swan-Ganz
  • Medicine
ispartof: Journal of the American College of Cardiology, 09 July 2019, Vol.74(1), pp.100-103
description: The tubing consistently coils up comfortably in the right atrium (RA).Outside-the-Box Intuition Some weekends later, pondering Danzig’s frustration as he sits on Santa Monica beach watching sailboats, Jeremy has a Newton-apple flash of inspiration: a catheter equipped with sheets and sails could pass through the RA, the right ventricle (RV), and then to the PA, carried by the force of blood behind it. Jeremy encourages George and me to test the balloon catheter in our MIRU. Because institutional review boards do not exist, George and I simply sterilize our catheter and go directly to our patient’s bedside. Comparing alternative drugs, we find our treatment decisions are repeatedly modified by bedside hemodynamics.Stroke of Chance Without doubt the most profound stroke of chance in the catheter’s development comes, not from medicine, but from politics. Thrombolytic therapy and angioplasty for acute MI in the 1990s lead to a dramatic decline in heart failure and cardiogenic shock.
language: eng
source:
identifier: ISSN: 0735-1097 ; E-ISSN: 1558-3597 ; DOI: 10.1016/j.jacc.2019.04.050
fulltext: no_fulltext
issn:
  • 0735-1097
  • 07351097
  • 1558-3597
  • 15583597
url: Link


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descriptionThe tubing consistently coils up comfortably in the right atrium (RA).Outside-the-Box Intuition Some weekends later, pondering Danzig’s frustration as he sits on Santa Monica beach watching sailboats, Jeremy has a Newton-apple flash of inspiration: a catheter equipped with sheets and sails could pass through the RA, the right ventricle (RV), and then to the PA, carried by the force of blood behind it. Jeremy encourages George and me to test the balloon catheter in our MIRU. Because institutional review boards do not exist, George and I simply sterilize our catheter and go directly to our patient’s bedside. Comparing alternative drugs, we find our treatment decisions are repeatedly modified by bedside hemodynamics.Stroke of Chance Without doubt the most profound stroke of chance in the catheter’s development comes, not from medicine, but from politics. Thrombolytic therapy and angioplasty for acute MI in the 1990s lead to a dramatic decline in heart failure and cardiogenic shock.
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