schliessen

Filtern

 

Bibliotheken

A Cost-Effectiveness Analysis of a Pilot Neonatal Screening Program for Sickle Cell Anemia in the Republic of Angola

To assess the cost-effectiveness of a pilot newborn screening (NBS) and treatment program for sickle cell anemia (SCA) in Luanda, Angola. In July 2011, a pilot NBS and treatment program was implemented in Luanda, Angola. Infants identified with SCA were enrolled in a specialized SCA clinic in which... Full description

Journal Title: The Journal of Pediatrics December 2015, Vol.167(6), pp.1314-1319
Main Author: Mcgann, Patrick T
Other Authors: Grosse, Scott D , Santos, Brigida , de Oliveira, Vysolela , Bernardino, Luis , Kassebaum, Nicholas J , Ware, Russell E , Airewele, Gladstone E
Format: Electronic Article Electronic Article
Language: English
Subjects:
ID: ISSN: 0022-3476 ; E-ISSN: 1097-6833 ; DOI: 10.1016/j.jpeds.2015.08.068
Link: https://www.sciencedirect.com/science/article/pii/S002234761501001X
Zum Text:
SendSend as email Add to Book BagAdd to Book Bag
Staff View
recordid: elsevier_sdoi_10_1016_j_jpeds_2015_08_068
title: A Cost-Effectiveness Analysis of a Pilot Neonatal Screening Program for Sickle Cell Anemia in the Republic of Angola
format: Article
creator:
  • Mcgann, Patrick T
  • Grosse, Scott D
  • Santos, Brigida
  • de Oliveira, Vysolela
  • Bernardino, Luis
  • Kassebaum, Nicholas J
  • Ware, Russell E
  • Airewele, Gladstone E
subjects:
  • Medicine
ispartof: The Journal of Pediatrics, December 2015, Vol.167(6), pp.1314-1319
description: To assess the cost-effectiveness of a pilot newborn screening (NBS) and treatment program for sickle cell anemia (SCA) in Luanda, Angola. In July 2011, a pilot NBS and treatment program was implemented in Luanda, Angola. Infants identified with SCA were enrolled in a specialized SCA clinic in which they received preventive care and sickle cell education. In this analysis, the World Health Organization (WHO) and generalized cost-effectiveness analysis methods were used to estimate gross intervention costs of the NBS and treatment program. To determine healthy life-years (HLYs) gained by screening and treatment, we assumed NBS reduced mortality to that of the Angolan population during the first 5 years based upon WHO and Global Burden of Diseases Study 2010 estimates, but provided no significant survival benefit for children who survive through age 5 years. A secondary sensitivity analysis with more conservative estimates of mortality benefits also was performed....
language: eng
source:
identifier: ISSN: 0022-3476 ; E-ISSN: 1097-6833 ; DOI: 10.1016/j.jpeds.2015.08.068
fulltext: fulltext
issn:
  • 0022-3476
  • 00223476
  • 1097-6833
  • 10976833
url: Link


@attributes
ID429097530
RANK0.07
NO1
SEARCH_ENGINEprimo_central_multiple_fe
SEARCH_ENGINE_TYPEPrimo Central Search Engine
LOCALfalse
PrimoNMBib
record
control
sourcerecordiddoi_10_1016_j_jpeds_2015_08_068
sourceidelsevier_s
recordidTN_elsevier_sdoi_10_1016_j_jpeds_2015_08_068
sourcesystemPC
dbid
0--K
1--M
2.FO
3.~1
41B1
51P~
61~.
7457
84G.
97-5
108P~
119JM
12AAEDT
13AAKOC
14AAOAW
15AAQFI
16ABBQC
17ABMZM
18ABYKQ
19ACDAQ
20ACRLP
21AEKER
22AEVXI
23AFKWA
24AFTJW
25AFXIZ
26AGHFR
27AGUBO
28AGYEJ
29AHHHB
30AIKHN
31AITUG
32AJBFU
33AJOXV
34AJRQY
35AJUYK
36AMFUW
37ANZVX
38BLXMC
39BNPGV
40FDB
41FGOYB
42FIRID
43FNPLU
44G-Q
45GBLVA
46HEF
47HMK
48HMO
49J1W
50KOM
51LCYCR
52OAUVE
53OH-
54OT-
55P-8
56P-9
57PC.
58Q38
59R2-
60RPZ
61SDF
62SEL
63SES
64SEW
65SSH
66SSZ
67T5K
68UV1
69Z5R
70~G-
pqid1737475888
galeid436985942
display
typearticle
titleA Cost-Effectiveness Analysis of a Pilot Neonatal Screening Program for Sickle Cell Anemia in the Republic of Angola
creatorMcgann, Patrick T ; Grosse, Scott D ; Santos, Brigida ; de Oliveira, Vysolela ; Bernardino, Luis ; Kassebaum, Nicholas J ; Ware, Russell E ; Airewele, Gladstone E
ispartofThe Journal of Pediatrics, December 2015, Vol.167(6), pp.1314-1319
identifier
subjectMedicine
descriptionTo assess the cost-effectiveness of a pilot newborn screening (NBS) and treatment program for sickle cell anemia (SCA) in Luanda, Angola. In July 2011, a pilot NBS and treatment program was implemented in Luanda, Angola. Infants identified with SCA were enrolled in a specialized SCA clinic in which they received preventive care and sickle cell education. In this analysis, the World Health Organization (WHO) and generalized cost-effectiveness analysis methods were used to estimate gross intervention costs of the NBS and treatment program. To determine healthy life-years (HLYs) gained by screening and treatment, we assumed NBS reduced mortality to that of the Angolan population during the first 5 years based upon WHO and Global Burden of Diseases Study 2010 estimates, but provided no significant survival benefit for children who survive through age 5 years. A secondary sensitivity analysis with more conservative estimates of mortality benefits also was performed....
languageeng
source
version5
lds50peer_reviewed
links
openurl$$Topenurl_article
openurlfulltext$$Topenurlfull_article
backlink$$Uhttps://www.sciencedirect.com/science/article/pii/S002234761501001X$$EView_record_in_ScienceDirect_(Access_to_full_text_may_be_restricted)
search
creatorcontrib
0Mcgann, Patrick T
1Grosse, Scott D
2Santos, Brigida
3de Oliveira, Vysolela
4Bernardino, Luis
5Kassebaum, Nicholas J
6Ware, Russell E
7Airewele, Gladstone E
titleA Cost-Effectiveness Analysis of a Pilot Neonatal Screening Program for Sickle Cell Anemia in the Republic of Angola
description

To assess the cost-effectiveness of a pilot newborn screening (NBS) and treatment program for sickle cell anemia (SCA) in Luanda, Angola.

In July 2011, a pilot NBS and treatment program was implemented in Luanda, Angola. Infants identified with SCA were enrolled in a specialized SCA clinic in which they received preventive care and sickle cell education. In this analysis, the World Health Organization (WHO) and generalized cost-effectiveness analysis methods were used to estimate gross intervention costs of the NBS and treatment program. To determine healthy life-years (HLYs) gained by screening and treatment, we assumed NBS reduced mortality to that of the Angolan population during the first 5 years based upon WHO and Global Burden of Diseases Study 2010 estimates, but provided no significant survival benefit for children who survive through age 5 years. A secondary sensitivity analysis with more conservative estimates of mortality benefits also was performed....

subjectMedicine
general
0English
1Elsevier Inc
210.1016/j.jpeds.2015.08.068
3ScienceDirect (Elsevier)
4ScienceDirect Journals (Elsevier)
sourceidelsevier_s
recordidelsevier_sdoi_10_1016_j_jpeds_2015_08_068
issn
00022-3476
100223476
21097-6833
310976833
rsrctypearticle
creationdate2015
addtitleThe Journal of Pediatrics
searchscope
0elsevier_full
1elsevier2
scope
0elsevier_full
1elsevier2
lsr44$$EView_record_in_ScienceDirect_(Access_to_full_text_may_be_restricted)
tmp01ScienceDirect Journals (Elsevier)
tmp02
0--K
1--M
2.FO
3.~1
41B1
51P~
61~.
7457
84G.
97-5
108P~
119JM
12AAEDT
13AAKOC
14AAOAW
15AAQFI
16ABBQC
17ABMZM
18ABYKQ
19ACDAQ
20ACRLP
21AEKER
22AEVXI
23AFKWA
24AFTJW
25AFXIZ
26AGHFR
27AGUBO
28AGYEJ
29AHHHB
30AIKHN
31AITUG
32AJBFU
33AJOXV
34AJRQY
35AJUYK
36AMFUW
37ANZVX
38BLXMC
39BNPGV
40FDB
41FGOYB
42FIRID
43FNPLU
44G-Q
45GBLVA
46HEF
47HMK
48HMO
49J1W
50KOM
51LCYCR
52OAUVE
53OH-
54OT-
55P-8
56P-9
57PC.
58Q38
59R2-
60RPZ
61SDF
62SEL
63SES
64SEW
65SSH
66SSZ
67T5K
68UV1
69Z5R
70~G-
startdate20151201
enddate20151231
lsr40The Journal of Pediatrics, December 2015, Vol.167 (6), pp.1314-1319
doi10.1016/j.jpeds.2015.08.068
citationpf 1314 pt 1319 vol 167 issue 6
lsr30VSR-Enriched:[pqid, galeid]
sort
titleA Cost-Effectiveness Analysis of a Pilot Neonatal Screening Program for Sickle Cell Anemia in the Republic of Angola
authorMcgann, Patrick T ; Grosse, Scott D ; Santos, Brigida ; de Oliveira, Vysolela ; Bernardino, Luis ; Kassebaum, Nicholas J ; Ware, Russell E ; Airewele, Gladstone E
creationdate20151200
lso0120151200
facets
frbrgroupid6908017380997604853
frbrtype5
newrecords20190904
languageeng
topicMedicine
collectionScienceDirect (Elsevier)
prefilterarticles
rsrctypearticles
creatorcontrib
0Mcgann, Patrick T
1Grosse, Scott D
2Santos, Brigida
3de Oliveira, Vysolela
4Bernardino, Luis
5Kassebaum, Nicholas J
6Ware, Russell E
7Airewele, Gladstone E
jtitleJournal of Pediatrics
creationdate2015
toplevelpeer_reviewed
delivery
delcategoryRemote Search Resource
fulltextfulltext
addata
aulast
0Mcgann
1Grosse
2Santos
3de Oliveira
4Bernardino
5Kassebaum
6Ware
7Airewele
aufirst
0Patrick T
1Scott D
2Brigida
3Vysolela
4Luis
5Nicholas J
6Russell E
7Gladstone E
auinitP
auinit1P
au
0Mcgann, Patrick T
1Grosse, Scott D
2Santos, Brigida
3de Oliveira, Vysolela
4Bernardino, Luis
5Kassebaum, Nicholas J
6Ware, Russell E
7Airewele, Gladstone E
atitleA Cost-Effectiveness Analysis of a Pilot Neonatal Screening Program for Sickle Cell Anemia in the Republic of Angola
jtitleThe Journal of Pediatrics
risdate201512
volume167
issue6
spage1314
epage1319
pages1314-1319
issn0022-3476
eissn1097-6833
formatjournal
genrearticle
ristypeJOUR
abstract

To assess the cost-effectiveness of a pilot newborn screening (NBS) and treatment program for sickle cell anemia (SCA) in Luanda, Angola.

In July 2011, a pilot NBS and treatment program was implemented in Luanda, Angola. Infants identified with SCA were enrolled in a specialized SCA clinic in which they received preventive care and sickle cell education. In this analysis, the World Health Organization (WHO) and generalized cost-effectiveness analysis methods were used to estimate gross intervention costs of the NBS and treatment program. To determine healthy life-years (HLYs) gained by screening and treatment, we assumed NBS reduced mortality to that of the Angolan population during the first 5 years based upon WHO and Global Burden of Diseases Study 2010 estimates, but provided no significant survival benefit for children who survive through age 5 years. A secondary sensitivity analysis with more conservative estimates of mortality benefits also was performed....

pubElsevier Inc
doi10.1016/j.jpeds.2015.08.068
lad01The Journal of Pediatrics
date2015-12