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A Fraxinus excelsior L. seeds/fruits extract benefits glucose homeostasis and adiposity related markers in elderly overweight/obese subjects: A longitudinal, randomized, crossover, double-blind, placebo-controlled nutritional intervention study

The aim of this study was to investigate the potential benefits of an extract obtained from seeds/fruits of an Oleaceae (Fraxinus excelsior L.) on glucose homeostasis and associated metabolic markers in non-diabetic overweight/obese subjects. This study was performed in 22 participants (50–80 years-... Full description

Journal Title: Phytomedicine 15 September 2014, Vol.21(10), pp.1162-1169
Main Author: Zulet, M.A
Other Authors: Navas-Carretero, S , Lara Y Sánchez, D , Abete, I , Flanagan, J , Issaly, N , Fança-Berthon, P , Bily, A , Roller, M , Martinez, J.A
Format: Electronic Article Electronic Article
Language: English
Subjects:
ID: ISSN: 0944-7113 ; E-ISSN: 1618-095X ; DOI: 10.1016/j.phymed.2014.04.027
Link: http://dx.doi.org/10.1016/j.phymed.2014.04.027
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recordid: elsevier_sdoi_10_1016_j_phymed_2014_04_027
title: A Fraxinus excelsior L. seeds/fruits extract benefits glucose homeostasis and adiposity related markers in elderly overweight/obese subjects: A longitudinal, randomized, crossover, double-blind, placebo-controlled nutritional intervention study
format: Article
creator:
  • Zulet, M.A
  • Navas-Carretero, S
  • Lara Y Sánchez, D
  • Abete, I
  • Flanagan, J
  • Issaly, N
  • Fança-Berthon, P
  • Bily, A
  • Roller, M
  • Martinez, J.A
subjects:
  • Fraxinus Excelsior L
  • Impaired Glucose Tolerance
  • Diabetes
  • Obesity
  • Herbal Medicine
  • Fructosamine
  • Fraxinus Excelsior L
  • Impaired Glucose Tolerance
  • Diabetes
  • Obesity
  • Herbal Medicine
  • Fructosamine
  • Medicine
  • Pharmacy, Therapeutics, & Pharmacology
ispartof: Phytomedicine, 15 September 2014, Vol.21(10), pp.1162-1169
description: The aim of this study was to investigate the potential benefits of an extract obtained from seeds/fruits of an Oleaceae (Fraxinus excelsior L.) on glucose homeostasis and associated metabolic markers in non-diabetic overweight/obese subjects. This study was performed in 22 participants (50–80 years-old; BMI 31.0kg/m2). The design was a longitudinal, randomized, crossover, double-blind, placebo-controlled 7-week nutritional intervention. The participants received daily 3 capsules each containing either 333mg of an extract from Fraxinus excelsior L. seeds (Glucevia®) or placebo capsules (control) in a random order for 3 weeks with 1 week of washout between treatments. Moreover, they followed a balanced covert energy-restricted diet (−15% energy). All variables were measured at the beginning and at the end of each period. Compared to baseline, the administration of 1g of Glucevia® for 3 weeks resulted in significantly lower incremental glucose...
language: eng
source:
identifier: ISSN: 0944-7113 ; E-ISSN: 1618-095X ; DOI: 10.1016/j.phymed.2014.04.027
fulltext: fulltext
issn:
  • 0944-7113
  • 09447113
  • 1618-095X
  • 1618095X
url: Link


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titleA Fraxinus excelsior L. seeds/fruits extract benefits glucose homeostasis and adiposity related markers in elderly overweight/obese subjects: A longitudinal, randomized, crossover, double-blind, placebo-controlled nutritional intervention study
creatorZulet, M.A ; Navas-Carretero, S ; Lara Y Sánchez, D ; Abete, I ; Flanagan, J ; Issaly, N ; Fança-Berthon, P ; Bily, A ; Roller, M ; Martinez, J.A
ispartofPhytomedicine, 15 September 2014, Vol.21(10), pp.1162-1169
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subjectFraxinus Excelsior L ; Impaired Glucose Tolerance ; Diabetes ; Obesity ; Herbal Medicine ; Fructosamine ; Fraxinus Excelsior L ; Impaired Glucose Tolerance ; Diabetes ; Obesity ; Herbal Medicine ; Fructosamine ; Medicine ; Pharmacy, Therapeutics, & Pharmacology
descriptionThe aim of this study was to investigate the potential benefits of an extract obtained from seeds/fruits of an Oleaceae (Fraxinus excelsior L.) on glucose homeostasis and associated metabolic markers in non-diabetic overweight/obese subjects. This study was performed in 22 participants (50–80 years-old; BMI 31.0kg/m2). The design was a longitudinal, randomized, crossover, double-blind, placebo-controlled 7-week nutritional intervention. The participants received daily 3 capsules each containing either 333mg of an extract from Fraxinus excelsior L. seeds (Glucevia®) or placebo capsules (control) in a random order for 3 weeks with 1 week of washout between treatments. Moreover, they followed a balanced covert energy-restricted diet (−15% energy). All variables were measured at the beginning and at the end of each period. Compared to baseline, the administration of 1g of Glucevia® for 3 weeks resulted in significantly lower incremental glucose...
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titleA Fraxinus excelsior L. seeds/fruits extract benefits glucose homeostasis and adiposity related markers in elderly overweight/obese subjects: A longitudinal, randomized, crossover, double-blind, placebo-controlled nutritional intervention study
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The aim of this study was to investigate the potential benefits of an extract obtained from seeds/fruits of an Oleaceae (Fraxinus excelsior L.) on glucose homeostasis and associated metabolic markers in non-diabetic overweight/obese subjects.

This study was performed in 22 participants (50–80 years-old; BMI 31.0kg/m2). The design was a longitudinal, randomized, crossover, double-blind, placebo-controlled 7-week nutritional intervention. The participants received daily 3 capsules each containing either 333mg of an extract from Fraxinus excelsior L. seeds (Glucevia®) or placebo capsules (control) in a random order for 3 weeks with 1 week of washout between treatments. Moreover, they followed a balanced covert energy-restricted diet (−15% energy). All variables were measured at the beginning and at the end of each period.

Compared to baseline, the administration of 1g of Glucevia® for 3 weeks resulted in significantly lower incremental glucose...

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abstract

The aim of this study was to investigate the potential benefits of an extract obtained from seeds/fruits of an Oleaceae (Fraxinus excelsior L.) on glucose homeostasis and associated metabolic markers in non-diabetic overweight/obese subjects.

This study was performed in 22 participants (50–80 years-old; BMI 31.0kg/m2). The design was a longitudinal, randomized, crossover, double-blind, placebo-controlled 7-week nutritional intervention. The participants received daily 3 capsules each containing either 333mg of an extract from Fraxinus excelsior L. seeds (Glucevia®) or placebo capsules (control) in a random order for 3 weeks with 1 week of washout between treatments. Moreover, they followed a balanced covert energy-restricted diet (−15% energy). All variables were measured at the beginning and at the end of each period.

Compared to baseline, the administration of 1g of Glucevia® for 3 weeks resulted in significantly lower incremental glucose...

pubElsevier GmbH
doi10.1016/j.phymed.2014.04.027
lad01Phytomedicine
date2014-09-15
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