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Kadpolysperins A–N, lanostane triterpene acids possessing rich structure types from Kadsura polysperma

Fourteen new lanostane triterpene acids ( – ), and five known analogues ( – ) were isolated from the stems of Compound , with a rearranged tetracyclic skeleton, is an important biogenic precursor of longipedlactone skeleton. Compounds – are members of 18(13→12)- -lanostane triterpene acids. The stru... Full description

Journal Title: Tetrahedron 17 June 2012, Vol.68(24), pp.4820-4829
Main Author: Dong, Ke
Other Authors: Pu, Jian-Xin , Du, Xue , Su, Jia , Li, Xiao-Nian , Yang, Jian-Hong , Zhao, Wei , Li, Yan , Sun, Han-Dong
Format: Electronic Article Electronic Article
Language: English
Subjects:
ID: ISSN: 0040-4020 ; E-ISSN: 1464-5416 ; DOI: 10.1016/j.tet.2012.03.116
Link: https://www.sciencedirect.com/science/article/pii/S0040402012004887
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recordid: elsevier_sdoi_10_1016_j_tet_2012_03_116
title: Kadpolysperins A–N, lanostane triterpene acids possessing rich structure types from Kadsura polysperma
format: Article
creator:
  • Dong, Ke
  • Pu, Jian-Xin
  • Du, Xue
  • Su, Jia
  • Li, Xiao-Nian
  • Yang, Jian-Hong
  • Zhao, Wei
  • Li, Yan
  • Sun, Han-Dong
subjects:
  • Kadsura Polysperma
  • Lanostane Triterpene Acid
  • Kadpolysperins
  • Cytotoxicity
  • Chemistry
ispartof: Tetrahedron, 17 June 2012, Vol.68(24), pp.4820-4829
description: Fourteen new lanostane triterpene acids ( – ), and five known analogues ( – ) were isolated from the stems of Compound , with a rearranged tetracyclic skeleton, is an important biogenic precursor of longipedlactone skeleton. Compounds – are members of 18(13→12)- -lanostane triterpene acids. The structures of new compounds were elucidated by spectroscopic evidence. Selected compounds were evaluated for their in vitro cytotoxicity against human tumor HL-60, SMMC-7721, A-549, MCF-7, and SW-480 cell lines.
language: eng
source:
identifier: ISSN: 0040-4020 ; E-ISSN: 1464-5416 ; DOI: 10.1016/j.tet.2012.03.116
fulltext: fulltext
issn:
  • 0040-4020
  • 00404020
  • 1464-5416
  • 14645416
url: Link


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titleKadpolysperins A–N, lanostane triterpene acids possessing rich structure types from Kadsura polysperma
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subjectKadsura Polysperma ; Lanostane Triterpene Acid ; Kadpolysperins ; Cytotoxicity ; Chemistry
descriptionFourteen new lanostane triterpene acids ( – ), and five known analogues ( – ) were isolated from the stems of Compound , with a rearranged tetracyclic skeleton, is an important biogenic precursor of longipedlactone skeleton. Compounds – are members of 18(13→12)- -lanostane triterpene acids. The structures of new compounds were elucidated by spectroscopic evidence. Selected compounds were evaluated for their in vitro cytotoxicity against human tumor HL-60, SMMC-7721, A-549, MCF-7, and SW-480 cell lines.
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