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Regioselective iodination of phenol and analogues using N-iodosuccinimide and p-toluenesulfonic acid

Highly regioselective para-iodinations of phenol and analogues are achieved at room temperature in high to excellent yields with a combination of p-toluenesulfonic acid and N-iodosuccinimide. Mild and highly regioselective monoiodination of phenol and analogues is achieved in high to excellent yield... Full description

Journal Title: Tetrahedron letters 2009, Vol.50 (22), p.2664-2667
Main Author: Bovonsombat, Pakorn
Other Authors: Leykajarakul, Juthamard , Khan, Chiraphorn , Pla-on, Kawin , Krause, Michael M , Khanthapura, Pratheep , Ali, Rameez , Doowa, Niran
Format: Electronic Article Electronic Article
Language: English
Subjects:
Publisher: Elsevier Ltd
ID: ISSN: 0040-4039
Zum Text:
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recordid: cdi_gale_infotracacademiconefile_A197993585
title: Regioselective iodination of phenol and analogues using N-iodosuccinimide and p-toluenesulfonic acid
format: Article
creator:
  • Bovonsombat, Pakorn
  • Leykajarakul, Juthamard
  • Khan, Chiraphorn
  • Pla-on, Kawin
  • Krause, Michael M
  • Khanthapura, Pratheep
  • Ali, Rameez
  • Doowa, Niran
subjects:
  • Chemical tests and reagents
  • Heterocyclic compounds
  • Phenols
ispartof: Tetrahedron letters, 2009, Vol.50 (22), p.2664-2667
description: Highly regioselective para-iodinations of phenol and analogues are achieved at room temperature in high to excellent yields with a combination of p-toluenesulfonic acid and N-iodosuccinimide. Mild and highly regioselective monoiodination of phenol and analogues is achieved in high to excellent yields at room temperature with a combination of stoichiometric p-toluenesulfonic acid and N-iodosuccinimide.
language: eng
source:
identifier: ISSN: 0040-4039
fulltext: no_fulltext
issn:
  • 0040-4039
  • 1873-3581
url: Link


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titleRegioselective iodination of phenol and analogues using N-iodosuccinimide and p-toluenesulfonic acid
creatorBovonsombat, Pakorn ; Leykajarakul, Juthamard ; Khan, Chiraphorn ; Pla-on, Kawin ; Krause, Michael M ; Khanthapura, Pratheep ; Ali, Rameez ; Doowa, Niran
creatorcontribBovonsombat, Pakorn ; Leykajarakul, Juthamard ; Khan, Chiraphorn ; Pla-on, Kawin ; Krause, Michael M ; Khanthapura, Pratheep ; Ali, Rameez ; Doowa, Niran
descriptionHighly regioselective para-iodinations of phenol and analogues are achieved at room temperature in high to excellent yields with a combination of p-toluenesulfonic acid and N-iodosuccinimide. Mild and highly regioselective monoiodination of phenol and analogues is achieved in high to excellent yields at room temperature with a combination of stoichiometric p-toluenesulfonic acid and N-iodosuccinimide.
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subjectChemical tests and reagents ; Heterocyclic compounds ; Phenols
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descriptionHighly regioselective para-iodinations of phenol and analogues are achieved at room temperature in high to excellent yields with a combination of p-toluenesulfonic acid and N-iodosuccinimide. Mild and highly regioselective monoiodination of phenol and analogues is achieved in high to excellent yields at room temperature with a combination of stoichiometric p-toluenesulfonic acid and N-iodosuccinimide.
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titleRegioselective iodination of phenol and analogues using N-iodosuccinimide and p-toluenesulfonic acid
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atitleRegioselective iodination of phenol and analogues using N-iodosuccinimide and p-toluenesulfonic acid
jtitleTetrahedron letters
date2009
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pages2664-2667
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abstractHighly regioselective para-iodinations of phenol and analogues are achieved at room temperature in high to excellent yields with a combination of p-toluenesulfonic acid and N-iodosuccinimide. Mild and highly regioselective monoiodination of phenol and analogues is achieved in high to excellent yields at room temperature with a combination of stoichiometric p-toluenesulfonic acid and N-iodosuccinimide.
pubElsevier Ltd
doi10.1016/j.tetlet.2009.03.128