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Regioselective iodination of phenol and analogues using N-iodosuccinimide and p-toluenesulfonic acid

Highly regioselective para-iodinations of phenol and analogues are achieved at room temperature in high to excellent yields with a combination of p-toluenesulfonic acid and N-iodosuccinimide. Mild and highly regioselective monoiodination of phenol and analogues is achieved in high to excellent yield... Full description

Journal Title: Tetrahedron Letters 2009, Vol.50(22), pp.2664-2667
Main Author: Bovonsombat, Pakorn
Other Authors: Leykajarakul, Juthamard , Khan, Chiraphorn , Pla-on, Kawin , Krause, Michael M , Khanthapura, Pratheep , Ali, Rameez , Doowa, Niran
Format: Electronic Article Electronic Article
Language: English
Subjects:
ID: ISSN: 0040-4039 ; E-ISSN: 1873-3581 ; DOI: 10.1016/j.tetlet.2009.03.128
Link: http://dx.doi.org/10.1016/j.tetlet.2009.03.128
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recordid: elsevier_sdoi_10_1016_j_tetlet_2009_03_128
title: Regioselective iodination of phenol and analogues using N-iodosuccinimide and p-toluenesulfonic acid
format: Article
creator:
  • Bovonsombat, Pakorn
  • Leykajarakul, Juthamard
  • Khan, Chiraphorn
  • Pla-on, Kawin
  • Krause, Michael M
  • Khanthapura, Pratheep
  • Ali, Rameez
  • Doowa, Niran
subjects:
  • Chemistry
ispartof: Tetrahedron Letters, 2009, Vol.50(22), pp.2664-2667
description: Highly regioselective para-iodinations of phenol and analogues are achieved at room temperature in high to excellent yields with a combination of p-toluenesulfonic acid and N-iodosuccinimide. Mild and highly regioselective monoiodination of phenol and analogues is achieved in high to excellent yields at room temperature with a combination of stoichiometric p-toluenesulfonic acid and N-iodosuccinimide.
language: eng
source:
identifier: ISSN: 0040-4039 ; E-ISSN: 1873-3581 ; DOI: 10.1016/j.tetlet.2009.03.128
fulltext: fulltext
issn:
  • 0040-4039
  • 00404039
  • 1873-3581
  • 18733581
url: Link


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titleRegioselective iodination of phenol and analogues using N-iodosuccinimide and p-toluenesulfonic acid
creatorBovonsombat, Pakorn ; Leykajarakul, Juthamard ; Khan, Chiraphorn ; Pla-on, Kawin ; Krause, Michael M ; Khanthapura, Pratheep ; Ali, Rameez ; Doowa, Niran
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descriptionHighly regioselective para-iodinations of phenol and analogues are achieved at room temperature in high to excellent yields with a combination of p-toluenesulfonic acid and N-iodosuccinimide. Mild and highly regioselective monoiodination of phenol and analogues is achieved in high to excellent yields at room temperature with a combination of stoichiometric p-toluenesulfonic acid and N-iodosuccinimide.
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titleRegioselective iodination of phenol and analogues using N-iodosuccinimide and p-toluenesulfonic acid
description

Highly regioselective para-iodinations of phenol and analogues are achieved at room temperature in high to excellent yields with a combination of p-toluenesulfonic acid and N-iodosuccinimide.

Mild and highly regioselective monoiodination of phenol and analogues is achieved in high to excellent yields at room temperature with a combination of stoichiometric p-toluenesulfonic acid and N-iodosuccinimide.

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abstract

Highly regioselective para-iodinations of phenol and analogues are achieved at room temperature in high to excellent yields with a combination of p-toluenesulfonic acid and N-iodosuccinimide.

Mild and highly regioselective monoiodination of phenol and analogues is achieved in high to excellent yields at room temperature with a combination of stoichiometric p-toluenesulfonic acid and N-iodosuccinimide.

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doi10.1016/j.tetlet.2009.03.128
lad01Tetrahedron Letters