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Trifluoromethanesulfonic acid-catalyzed solvent-free bisindolylation of trifluoromethyl ketones

A trifluoromethanesulfonic acid-catalyzed solvent-free bisindolylation reaction of indoles with alkyl and aryl trifluoromethyl ketones has been developed. The trifluoromethyl-substituted bisindolylalkane derivatives were synthesized in moderate to excellent yields.

Journal Title: Tetrahedron Letters 29 January 2014, Vol.55(5), pp.1045-1048
Main Author: Wang, Yi
Other Authors: Yuan, Yu , Xing, Chun-Hui , Lu, Long
Format: Electronic Article Electronic Article
Language: English
Subjects:
ID: ISSN: 0040-4039 ; E-ISSN: 1873-3581 ; DOI: 10.1016/j.tetlet.2013.12.078
Link: https://www.sciencedirect.com/science/article/pii/S0040403913021643
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recordid: elsevier_sdoi_10_1016_j_tetlet_2013_12_078
title: Trifluoromethanesulfonic acid-catalyzed solvent-free bisindolylation of trifluoromethyl ketones
format: Article
creator:
  • Wang, Yi
  • Yuan, Yu
  • Xing, Chun-Hui
  • Lu, Long
subjects:
  • Bisindolylation
  • Solvent-Free
  • Trifluoromethyl Ketone
  • Indole
  • Trifluoromethanesulfonic Acid
  • Chemistry
ispartof: Tetrahedron Letters, 29 January 2014, Vol.55(5), pp.1045-1048
description: A trifluoromethanesulfonic acid-catalyzed solvent-free bisindolylation reaction of indoles with alkyl and aryl trifluoromethyl ketones has been developed. The trifluoromethyl-substituted bisindolylalkane derivatives were synthesized in moderate to excellent yields.
language: eng
source:
identifier: ISSN: 0040-4039 ; E-ISSN: 1873-3581 ; DOI: 10.1016/j.tetlet.2013.12.078
fulltext: fulltext
issn:
  • 0040-4039
  • 00404039
  • 1873-3581
  • 18733581
url: Link


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subjectBisindolylation ; Solvent-Free ; Trifluoromethyl Ketone ; Indole ; Trifluoromethanesulfonic Acid ; Chemistry
descriptionA trifluoromethanesulfonic acid-catalyzed solvent-free bisindolylation reaction of indoles with alkyl and aryl trifluoromethyl ketones has been developed. The trifluoromethyl-substituted bisindolylalkane derivatives were synthesized in moderate to excellent yields.
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abstract

A trifluoromethanesulfonic acid-catalyzed solvent-free bisindolylation reaction of indoles with alkyl and aryl trifluoromethyl ketones has been developed. The trifluoromethyl-substituted bisindolylalkane derivatives were synthesized in moderate to excellent yields.

pubElsevier Ltd
doi10.1016/j.tetlet.2013.12.078
lad01Tetrahedron Letters
date2014-01-29