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Bioprinting for stem cell research

Recently, there has been growing interest in applying bioprinting techniques to stem cell research. Several bioprinting methods have been developed utilizing acoustics, piezoelectricity, and lasers to deposit living cells onto receiving substrates. Using these technologies, spatially defined gradien... Full description

Journal Title: Trends in Biotechnology January 2013, Vol.31(1), pp.10-19
Main Author: Tasoglu, Savas
Other Authors: Demirci, Utkan
Format: Electronic Article Electronic Article
Language: English
Subjects:
ID: ISSN: 0167-7799 ; E-ISSN: 1879-3096 ; DOI: 10.1016/j.tibtech.2012.10.005
Link: https://www.sciencedirect.com/science/article/pii/S0167779912001850
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title: Bioprinting for stem cell research
format: Article
creator:
  • Tasoglu, Savas
  • Demirci, Utkan
subjects:
  • Engineering
  • Chemistry
ispartof: Trends in Biotechnology, January 2013, Vol.31(1), pp.10-19
description: Recently, there has been growing interest in applying bioprinting techniques to stem cell research. Several bioprinting methods have been developed utilizing acoustics, piezoelectricity, and lasers to deposit living cells onto receiving substrates. Using these technologies, spatially defined gradients of immobilized biomolecules can be engineered to direct stem cell differentiation into multiple subpopulations of different lineages. Stem cells can also be patterned in a high-throughput manner onto flexible implementation patches for tissue regeneration or onto substrates with the goal of accessing encapsulated stem cells of interest for genomic analysis. Here, we review recent achievements with bioprinting technologies in stem cell research, and identify future challenges and potential applications including tissue engineering and regenerative medicine, wound healing, and genomics.
language: eng
source:
identifier: ISSN: 0167-7799 ; E-ISSN: 1879-3096 ; DOI: 10.1016/j.tibtech.2012.10.005
fulltext: no_fulltext
issn:
  • 0167-7799
  • 01677799
  • 1879-3096
  • 18793096
url: Link


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descriptionRecently, there has been growing interest in applying bioprinting techniques to stem cell research. Several bioprinting methods have been developed utilizing acoustics, piezoelectricity, and lasers to deposit living cells onto receiving substrates. Using these technologies, spatially defined gradients of immobilized biomolecules can be engineered to direct stem cell differentiation into multiple subpopulations of different lineages. Stem cells can also be patterned in a high-throughput manner onto flexible implementation patches for tissue regeneration or onto substrates with the goal of accessing encapsulated stem cells of interest for genomic analysis. Here, we review recent achievements with bioprinting technologies in stem cell research, and identify future challenges and potential applications including tissue engineering and regenerative medicine, wound healing, and genomics.
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Recently, there has been growing interest in applying bioprinting techniques to stem cell research. Several bioprinting methods have been developed utilizing acoustics, piezoelectricity, and lasers to deposit living cells onto receiving substrates. Using these technologies, spatially defined gradients of immobilized biomolecules can be engineered to direct stem cell differentiation into multiple subpopulations of different lineages. Stem cells can also be patterned in a high-throughput manner onto flexible implementation patches for tissue regeneration or onto substrates with the goal of accessing encapsulated stem cells of interest for genomic analysis. Here, we review recent achievements with bioprinting technologies in stem cell research, and identify future challenges and potential applications including tissue engineering and regenerative medicine, wound healing, and genomics.

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