Comparison of Asian porcine high fever disease isolates of porcine reproductive and respiratory syndrome virus to United States isolates for their ability to cause disease and secondary bacterial infection in swine
Journal Title: | Veterinary microbiology May 2017, Vol.203, pp.6-17 |
Main Author: | Brockmeier, Susan L |
Other Authors: | Loving, Crystal L , Palmer, Mitchel V , Spear, Allyn , Nicholson, Tracy L , Faaberg, Kay S , Lager, Kelly M |
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ID: | ISSN: 0378-1135 ; E-ISSN: 1873-2542 ; DOI: 10.1016/j.vetmic.2017.02.003 |
Link: | http://dx.doi.org/10.1016/j.vetmic.2017.02.003 |
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recordid: | elsevier_sdoi_10_1016_j_vetmic_2017_02_003 |
title: | Comparison of Asian porcine high fever disease isolates of porcine reproductive and respiratory syndrome virus to United States isolates for their ability to cause disease and secondary bacterial infection in swine |
format: | Article |
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ispartof: | Veterinary microbiology, May 2017, Vol.203, pp.6-17 |
description: | •Both Asian HP-PRRSV isolates and US PRRSV isolates varied in virulence.•The frequency of secondary bacterial pneumonia was associated with the virulence of the PRRSV strains evaluated.•Serum cytokine levels tended to be lower for pigs coinfected with virus and bacteria compared to pigs infected with PRRSV alone.•Factors such as bacterial burden, age at the time of exposure, and stress play an important role in the outcome of infection with PRRSV. Epidemiologic data from Asian outbreaks of highly-pathogenic (HP) porcine reproductive and respiratory syndrome virus (PRRSV) suggest that disease severity was associated with both the virulence of the PRRSV isolates and secondary bacterial infections. Previous reports have indicated that U.S. isolates of PRRSV predispose to secondary bacterial infections as well, but the severity of disease that occurred in Asia in pigs infected with these HP-PRRSV strains has not been reported in the U.S. The objectives of this research... |
language: | eng |
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identifier: | ISSN: 0378-1135 ; E-ISSN: 1873-2542 ; DOI: 10.1016/j.vetmic.2017.02.003 |
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