schliessen

Filtern

 

Bibliotheken

Effects of acute dietary restriction on gut motor, hormone and energy intake responses to duodenal fat in obese men

Background: Previous patterns of energy intake influence gastrointestinal function and appetite, probably reflecting changes in small-intestinal nutrient-mediated feedback. Obese individuals consume more fat and may be less sensitive to its gastrointestinal and appetite-suppressant effects than lean... Full description

Journal Title: International journal of obesity 2011, Vol.35(3), pp.448-456
Main Author: Brennan , I.M.
Other Authors: Seimon , R.B. , Luscombe-Marsh , N.D. , Otto , B. , Horowitz , M. , Feinle-Bisset , C.
Format: Electronic Article Electronic Article
Language: English
Subjects:
Men
ID: ISSN: 0307-0565
Zum Text:
SendSend as email Add to Book BagAdd to Book Bag
Staff View
recordid: faoagrisUS201500073196
title: Effects of acute dietary restriction on gut motor, hormone and energy intake responses to duodenal fat in obese men
format: Article
creator:
  • Brennan , I.M.
  • Seimon , R.B.
  • Luscombe-Marsh , N.D.
  • Otto , B.
  • Horowitz , M.
  • Feinle-Bisset , C.
subjects:
  • Gastrointestinal Motility
  • Cholecystokinin
  • Body Mass Index
  • Males
  • Peptide Yy
  • Dietary Restriction
  • Hunger
  • Acute Effects
  • Very Low Calorie Diet
  • Ghrelin
  • Energy Intake
  • Men
  • Gastrointestinal System
ispartof: International journal of obesity, 2011, Vol.35(3), pp.448-456
description: Background: Previous patterns of energy intake influence gastrointestinal function and appetite, probably reflecting changes in small-intestinal nutrient-mediated feedback. Obese individuals consume more fat and may be less sensitive to its gastrointestinal and appetite-suppressant effects than lean individuals. Objective: To evaluate the hypothesis that, in obese individuals, the effects of duodenal fat on gastrointestinal motor and hormone function, and appetite would be enhanced by a short period on a very-low-calorie diet (VLCD). Methods: Eight obese men (body mass index 34±0.6 kg m−2) were studied on two occasions, before (V1), and immediately after (V2), a 4-day VLCD. On both occasions, antropyloroduodenal motility, plasma cholecystokinin (CCK), peptide-YY (PYY) and ghrelin concentrations, and appetite perceptions were measured during a 120-min intraduodenal fat infusion (2.86 kcal min−1). Immediately afterwards, energy intake was quantified. Results: During V2, basal pyloric pressure and the number and amplitude of isolated pyloric pressure waves (PWs) were greater, whereas the number of antral and duodenal PWs was less, compared with V1 (all P
language: eng
source:
identifier: ISSN: 0307-0565
fulltext: fulltext
issn:
  • 03070565
  • 0307-0565
url: Link


@attributes
ID1565765006
RANK0.07
NO1
SEARCH_ENGINEprimo_central_multiple_fe
SEARCH_ENGINE_TYPEPrimo Central Search Engine
LOCALfalse
PrimoNMBib
record
control
sourcerecordidUS201500073196
sourceidfaoagris
recordidTN_faoagrisUS201500073196
sourcesystemOther
pqid857290635
galeid252555220
display
typearticle
titleEffects of acute dietary restriction on gut motor, hormone and energy intake responses to duodenal fat in obese men
creatorBrennan , I.M. ; Seimon , R.B. ; Luscombe-Marsh , N.D. ; Otto , B. ; Horowitz , M. ; Feinle-Bisset , C.
ispartofInternational journal of obesity, 2011, Vol.35(3), pp.448-456
identifierISSN: 0307-0565
subjectGastrointestinal Motility ; Cholecystokinin ; Body Mass Index ; Males ; Peptide Yy ; Dietary Restriction ; Hunger ; Acute Effects ; Very Low Calorie Diet ; Ghrelin ; Energy Intake ; Men ; Gastrointestinal System
descriptionBackground: Previous patterns of energy intake influence gastrointestinal function and appetite, probably reflecting changes in small-intestinal nutrient-mediated feedback. Obese individuals consume more fat and may be less sensitive to its gastrointestinal and appetite-suppressant effects than lean individuals. Objective: To evaluate the hypothesis that, in obese individuals, the effects of duodenal fat on gastrointestinal motor and hormone function, and appetite would be enhanced by a short period on a very-low-calorie diet (VLCD). Methods: Eight obese men (body mass index 34±0.6 kg m−2) were studied on two occasions, before (V1), and immediately after (V2), a 4-day VLCD. On both occasions, antropyloroduodenal motility, plasma cholecystokinin (CCK), peptide-YY (PYY) and ghrelin concentrations, and appetite perceptions were measured during a 120-min intraduodenal fat infusion (2.86 kcal min−1). Immediately afterwards, energy intake was quantified. Results: During V2, basal pyloric pressure and the number and amplitude of isolated pyloric pressure waves (PWs) were greater, whereas the number of antral and duodenal PWs was less, compared with V1 (all P<0.05). Moreover, during V2, baseline ghrelin concentration was higher; the stimulation of PYY and suppression of ghrelin by lipid were greater, with no difference in CCK concentration; and hunger and energy intake (kJ; V1: 4378±691, V2: 3634±700) were less (all P<0.05), compared with V1. Conclusions: In obese males, the effects of small-intestinal lipid on gastrointestinal motility and some hormone responses and appetite are enhanced after a 4-day VLCD. ; Includes references ; p. 448-456.
languageeng
source
version9
lds50peer_reviewed
links
openurl$$Topenurl_article
linktorsrc$$Uhttp://dx.doi.org/10.1038/ijo.2010.153$$EView_full_text_(authentication_may_be_required)
openurlfulltext$$Topenurlfull_article
search
creatorcontrib
0Brennan , I.M.
1Seimon , R.B.
2Luscombe-Marsh , N.D.
3Otto , B.
4Horowitz , M.
5Feinle-Bisset , C.
titleEffects of acute dietary restriction on gut motor, hormone and energy intake responses to duodenal fat in obese men
descriptionBackground: Previous patterns of energy intake influence gastrointestinal function and appetite, probably reflecting changes in small-intestinal nutrient-mediated feedback. Obese individuals consume more fat and may be less sensitive to its gastrointestinal and appetite-suppressant effects than lean individuals. Objective: To evaluate the hypothesis that, in obese individuals, the effects of duodenal fat on gastrointestinal motor and hormone function, and appetite would be enhanced by a short period on a very-low-calorie diet (VLCD). Methods: Eight obese men (body mass index 34±0.6 kg m−2) were studied on two occasions, before (V1), and immediately after (V2), a 4-day VLCD. On both occasions, antropyloroduodenal motility, plasma cholecystokinin (CCK), peptide-YY (PYY) and ghrelin concentrations, and appetite perceptions were measured during a 120-min intraduodenal fat infusion (2.86 kcal min−1). Immediately afterwards, energy intake was quantified. Results: During V2, basal pyloric pressure and the number and amplitude of isolated pyloric pressure waves (PWs) were greater, whereas the number of antral and duodenal PWs was less, compared with V1 (all P<0.05). Moreover, during V2, baseline ghrelin concentration was higher; the stimulation of PYY and suppression of ghrelin by lipid were greater, with no difference in CCK concentration; and hunger and energy intake (kJ; V1: 4378±691, V2: 3634±700) were less (all P<0.05), compared with V1. Conclusions: In obese males, the effects of small-intestinal lipid on gastrointestinal motility and some hormone responses and appetite are enhanced after a 4-day VLCD. ; Includes references ; p. 448-456.
subject
0Gastrointestinal Motility
1Cholecystokinin
2Body Mass Index
3Males
4Peptide Yy
5Dietary Restriction
6Hunger
7Acute Effects
8Very Low Calorie Diet
9Ghrelin
10Energy Intake
11Men
12Gastrointestinal System
general
0English
1AGRIS (United Nations, Food and Agriculture Organization)
sourceidfaoagris
recordidfaoagrisUS201500073196
rsrctypearticle
creationdate2011
addtitleInternational journal of obesity
searchscope
0faoagris
1faoagris_lr
scope
0faoagris
1faoagris_lr
alttitleEffects of acute dietary restriction on gut motor, hormone and energy intake responses to duodenal fat in obese men
issn
003070565
10307-0565
lsr30VSR-Enriched:[pqid, eissn, galeid, doi]
sort
titleEffects of acute dietary restriction on gut motor, hormone and energy intake responses to duodenal fat in obese men
authorBrennan , I.M. ; Seimon , R.B. ; Luscombe-Marsh , N.D. ; Otto , B. ; Horowitz , M. ; Feinle-Bisset , C.
creationdate20110000
facets
frbrgroupid8207586504728892332
frbrtype5
languageeng
creationdate2011
topic
0Gastrointestinal Motility
1Cholecystokinin
2Body Mass Index
3Males
4Peptide Yy
5Dietary Restriction
6Hunger
7Acute Effects
8Very Low Calorie Diet
9Ghrelin
10Energy Intake
11Men
12Gastrointestinal System
collectionAGRIS (United Nations, Food and Agriculture Organization)
prefilterarticles
rsrctypearticles
creatorcontrib
0Brennan , I.M.
1Seimon , R.B.
2Luscombe-Marsh , N.D.
3Otto , B.
4Horowitz , M.
5Feinle-Bisset , C.
jtitleInternational journal of obesity
toplevelpeer_reviewed
delivery
delcategoryRemote Search Resource
fulltextfulltext
addata
au
0Brennan, I.M.
1Seimon, R.B.
2Luscombe-Marsh, N.D.
3Otto, B.
4Horowitz, M.
5Feinle-Bisset, C.
atitleEffects of acute dietary restriction on gut motor, hormone and energy intake responses to duodenal fat in obese men
jtitleInternational journal of obesity
addtitleEffects of acute dietary restriction on gut motor, hormone and energy intake responses to duodenal fat in obese men
date2011
risdate2011
volume35
issue3
spage448
epage456
pages448-456
issn0307-0565
formatjournal
genrearticle
ristypeJOUR
notesIncludes references
abstractBackground: Previous patterns of energy intake influence gastrointestinal function and appetite, probably reflecting changes in small-intestinal nutrient-mediated feedback. Obese individuals consume more fat and may be less sensitive to its gastrointestinal and appetite-suppressant effects than lean individuals. Objective: To evaluate the hypothesis that, in obese individuals, the effects of duodenal fat on gastrointestinal motor and hormone function, and appetite would be enhanced by a short period on a very-low-calorie diet (VLCD). Methods: Eight obese men (body mass index 34±0.6 kg m−2) were studied on two occasions, before (V1), and immediately after (V2), a 4-day VLCD. On both occasions, antropyloroduodenal motility, plasma cholecystokinin (CCK), peptide-YY (PYY) and ghrelin concentrations, and appetite perceptions were measured during a 120-min intraduodenal fat infusion (2.86 kcal min−1). Immediately afterwards, energy intake was quantified. Results: During V2, basal pyloric pressure and the number and amplitude of isolated pyloric pressure waves (PWs) were greater, whereas the number of antral and duodenal PWs was less, compared with V1 (all P<0.05). Moreover, during V2, baseline ghrelin concentration was higher; the stimulation of PYY and suppression of ghrelin by lipid were greater, with no difference in CCK concentration; and hunger and energy intake (kJ; V1: 4378±691, V2: 3634±700) were less (all P<0.05), compared with V1. Conclusions: In obese males, the effects of small-intestinal lipid on gastrointestinal motility and some hormone responses and appetite are enhanced after a 4-day VLCD.
pubNature Publishing Group
doi10.1038/ijo.2010.153
eissn14765497