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Structural and conformational requisites in DNA quadruplex groove binding: another piece to the puzzle.(Report)

Several studies are conducted to determine the structural and conformational requisites that are required for the DNA quadruplex groove binding. Distamycin A is shown to be the only compound exhibiting a pure groove binding.

Journal Title: Journal of the American Chemical Society May 12, 2010, Vol.132(18), p.6425-6433
Main Author: Cosconati, Sandro
Other Authors: Marinelli, Luciana , Trotta, Roberta , Virno, Ada , De Tito, Stefano , Romagnoli, Romeo , Pagano, Bruno , Limongelli, Vittorio , Giancola, Concetta , Baraldi, Pier Giovanni , Mayo, Luciano , Novellino, Ettore , Randazzo, Antonio
Format: Electronic Article Electronic Article
Language: English
Subjects:
ID: ISSN: 0002-7863
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recordid: gale_ofa226755750
title: Structural and conformational requisites in DNA quadruplex groove binding: another piece to the puzzle.(Report)
format: Article
creator:
  • Cosconati, Sandro
  • Marinelli, Luciana
  • Trotta, Roberta
  • Virno, Ada
  • De Tito, Stefano
  • Romagnoli, Romeo
  • Pagano, Bruno
  • Limongelli, Vittorio
  • Giancola, Concetta
  • Baraldi, Pier Giovanni
  • Mayo, Luciano
  • Novellino, Ettore
  • Randazzo, Antonio
subjects:
  • Antineoplastic Agents -- Chemical Properties
  • Dna -- Structure
  • Dna -- Chemical Properties
  • Dna Binding -- Analysis
  • Electrostatic Interactions -- Analysis
ispartof: Journal of the American Chemical Society, May 12, 2010, Vol.132(18), p.6425-6433
description: Several studies are conducted to determine the structural and conformational requisites that are required for the DNA quadruplex groove binding. Distamycin A is shown to be the only compound exhibiting a pure groove binding.
language: English
source:
identifier: ISSN: 0002-7863
fulltext: no_fulltext
issn:
  • 0002-7863
  • 00027863
url: Link


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titleStructural and conformational requisites in DNA quadruplex groove binding: another piece to the puzzle.(Report)
creatorCosconati, Sandro ; Marinelli, Luciana ; Trotta, Roberta ; Virno, Ada ; De Tito, Stefano ; Romagnoli, Romeo ; Pagano, Bruno ; Limongelli, Vittorio ; Giancola, Concetta ; Baraldi, Pier Giovanni ; Mayo, Luciano ; Novellino, Ettore ; Randazzo, Antonio
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identifierISSN: 0002-7863
subjectAntineoplastic Agents -- Chemical Properties ; Dna -- Structure ; Dna -- Chemical Properties ; Dna Binding -- Analysis ; Electrostatic Interactions -- Analysis
descriptionSeveral studies are conducted to determine the structural and conformational requisites that are required for the DNA quadruplex groove binding. Distamycin A is shown to be the only compound exhibiting a pure groove binding.
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titleStructural and conformational requisites in DNA quadruplex groove binding: another piece to the puzzle.(Report)
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abstractSeveral studies are conducted to determine the structural and conformational requisites that are required for the DNA quadruplex groove binding. Distamycin A is shown to be the only compound exhibiting a pure groove binding.
pubAmerican Chemical Society
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date2010-05-12