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Targeted Delivery System of Nanobiomaterials in Anticancer Therapy: From Cells to Clinics

Targeted delivery systems of nanobiomaterials are necessary to be developed for the diagnosis and treatment of cancer. Nanobiomaterials can be engineered to recognize cancer-specific receptors at the cellular levels and to deliver anticancer drugs into the diseased sites. In particular, nanobiomater... Full description

Journal Title: BioMed Research International 2014, Vol.2014, 23 pages
Main Author: Jin, Su-Eon
Other Authors: Jin, Hyo-Eon , Hong, Soon-Sun
Format: Electronic Article Electronic Article
Language:
Subjects:
ID: ISSN: 2314-6133 ; E-ISSN: 2314-6141 ; DOI: 10.1155/2014/814208
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recordid: hindawi10.1155/2014/814208
title: Targeted Delivery System of Nanobiomaterials in Anticancer Therapy: From Cells to Clinics
format: Article
creator:
  • Jin, Su-Eon
  • Jin, Hyo-Eon
  • Hong, Soon-Sun
subjects:
  • Review Article
ispartof: BioMed Research International, 2014, Vol.2014, 23 pages
description: Targeted delivery systems of nanobiomaterials are necessary to be developed for the diagnosis and treatment of cancer. Nanobiomaterials can be engineered to recognize cancer-specific receptors at the cellular levels and to deliver anticancer drugs into the diseased sites. In particular, nanobiomaterial-based nanocarriers, so-called nanoplatforms, are the design of the targeted delivery systems such as liposomes, polymeric nanoparticles/micelles, nanoconjugates, norganic materials, carbon-based nanobiomaterials, and bioinspired phage system, which are based on the nanosize of 1–100 nm in diameter. In this review, the design and the application of these nanoplatforms are discussed at the cellular levels as well as in the clinics. We believe that this review can offer recent advances in the targeted delivery systems of nanobiomaterials regarding and applications and the translation of nanobiomaterials to nanomedicine in anticancer therapy.
language:
source:
identifier: ISSN: 2314-6133 ; E-ISSN: 2314-6141 ; DOI: 10.1155/2014/814208
fulltext: fulltext
issn:
  • 2314-6133
  • 23146133
  • 2314-6141
  • 23146141
url: Link


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abstractTargeted delivery systems of nanobiomaterials are necessary to be developed for the diagnosis and treatment of cancer. Nanobiomaterials can be engineered to recognize cancer-specific receptors at the cellular levels and to deliver anticancer drugs into the diseased sites. In particular, nanobiomaterial-based nanocarriers, so-called nanoplatforms, are the design of the targeted delivery systems such as liposomes, polymeric nanoparticles/micelles, nanoconjugates, norganic materials, carbon-based nanobiomaterials, and bioinspired phage system, which are based on the nanosize of 1–100 nm in diameter. In this review, the design and the application of these nanoplatforms are discussed at the cellular levels as well as in the clinics. We believe that this review can offer recent advances in the targeted delivery systems of nanobiomaterials regarding and applications and the translation of nanobiomaterials to nanomedicine in anticancer therapy.
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