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Liposomes containing lipid A: an effective, safe, generic adjuvant system for synthetic vaccines

Liposomes containing monophosphoryl lipid A (MPLA) have previously exhibited considerable potency and safety in human trials with a variety of candidate vaccines, including vaccines to malaria, HIV-1 and several different types of cancer. The long history of research and development of MPLA...

Journal Title: Expert Review of Vaccines 01 June 2012, Vol.11(6), pp.733-744
Main Author: Alving, Carl R
Other Authors: Rao, Mangala , Steers, Nicholas J , Matyas, Gary R , Mayorov, Alexander V
Format: Electronic Article Electronic Article
Language: English
Subjects:
ID: ISSN: 1476-0584 ; E-ISSN: 1744-8395 ; DOI: 10.1586/erv.12.35
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recordid: informaworld_s10_1586_erv_12_35
title: Liposomes containing lipid A: an effective, safe, generic adjuvant system for synthetic vaccines
format: Article
creator:
  • Alving, Carl R
  • Rao, Mangala
  • Steers, Nicholas J
  • Matyas, Gary R
  • Mayorov, Alexander V
subjects:
  • Adjuvant
  • Adjuvant Mechanisms
  • Adjuvant Systems
  • Data Mining
  • Lipid A
  • Liposomes
  • Monophosphoryl Lipid A
  • Patents and Intellectual Property
  • Peptide Vaccines
  • Biology
ispartof: Expert Review of Vaccines, 01 June 2012, Vol.11(6), pp.733-744
description: Liposomes containing monophosphoryl lipid A (MPLA) have previously exhibited considerable potency and safety in human trials with a variety of candidate vaccines, including vaccines to malaria, HIV-1 and several different types of cancer. The long history of research and development of MPLA...
language: eng
source:
identifier: ISSN: 1476-0584 ; E-ISSN: 1744-8395 ; DOI: 10.1586/erv.12.35
fulltext: fulltext
issn:
  • 1476-0584
  • 14760584
  • 1744-8395
  • 17448395
url: Link


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subjectAdjuvant ; Adjuvant Mechanisms ; Adjuvant Systems ; Data Mining ; Lipid A ; Liposomes ; Monophosphoryl Lipid A ; Patents and Intellectual Property ; Peptide Vaccines ; Biology
descriptionLiposomes containing monophosphoryl lipid A (MPLA) have previously exhibited considerable potency and safety in human trials with a variety of candidate vaccines, including vaccines to malaria, HIV-1 and several different types of cancer. The long history of research and development of MPLA...
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Liposomes containing monophosphoryl lipid A (MPLA) have previously exhibited considerable potency and safety in human trials with a variety of candidate vaccines, including vaccines to malaria, HIV-1 and several different types of cancer. The long history of research and development of MPLA...

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lad01Expert Review of Vaccines
date2012-06-01