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Fabrication and characterization of paper-based microfluidics prepared in nitrocellulose membrane by wax printing

Paper-based microfluidics is a promising technology to develop a simple, low-cost, portable, and disposable diagnostic platform for resource-limited settings. Here we report the fabrication of paper-based microfluidic devices in nitrocellulose membrane by wax printing for protein immobilization rela... Full description

Journal Title: Analytical chemistry 01 January 2010, Vol.82(1), pp.329-35
Main Author: Lu, Yao
Other Authors: Shi, Weiwei , Qin, Jianhua , Lin, Bingcheng
Format: Electronic Article Electronic Article
Language: English
Subjects:
ID: E-ISSN: 1520-6882 ; PMID: 20000582 Version:1 ; DOI: 10.1021/ac9020193
Link: http://pubmed.gov/20000582
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recordid: medline20000582
title: Fabrication and characterization of paper-based microfluidics prepared in nitrocellulose membrane by wax printing
format: Article
creator:
  • Lu, Yao
  • Shi, Weiwei
  • Qin, Jianhua
  • Lin, Bingcheng
subjects:
  • Membranes, Artificial
  • Paper
  • Waxes
  • Collodion -- Chemistry
  • Microfluidics -- Instrumentation
ispartof: Analytical chemistry, 01 January 2010, Vol.82(1), pp.329-35
description: Paper-based microfluidics is a promising technology to develop a simple, low-cost, portable, and disposable diagnostic platform for resource-limited settings. Here we report the fabrication of paper-based microfluidic devices in nitrocellulose membrane by wax printing for protein immobilization related applications. The fabrication process, which can be finished within 10 min, includes mainly printing and baking steps. Wax patterning will form hydrophobic regions in the membrane, which can be used to direct the flow path or separate reaction zones. The fabrication parameters like printing mode and baking time were optimized, and performances of the wax-patterned nitrocellulose membrane such as printing resolution, protein immobilization, and sample purification capabilities were also characterized in this report. We believe the wax-patterned nitrocellulose membrane will enhance the capabilities of paper microfluidic devices and bring new applications in this field.
language: eng
source:
identifier: E-ISSN: 1520-6882 ; PMID: 20000582 Version:1 ; DOI: 10.1021/ac9020193
fulltext: fulltext
issn:
  • 15206882
  • 1520-6882
url: Link


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titleFabrication and characterization of paper-based microfluidics prepared in nitrocellulose membrane by wax printing
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subjectMembranes, Artificial ; Paper ; Waxes ; Collodion -- Chemistry ; Microfluidics -- Instrumentation
descriptionPaper-based microfluidics is a promising technology to develop a simple, low-cost, portable, and disposable diagnostic platform for resource-limited settings. Here we report the fabrication of paper-based microfluidic devices in nitrocellulose membrane by wax printing for protein immobilization related applications. The fabrication process, which can be finished within 10 min, includes mainly printing and baking steps. Wax patterning will form hydrophobic regions in the membrane, which can be used to direct the flow path or separate reaction zones. The fabrication parameters like printing mode and baking time were optimized, and performances of the wax-patterned nitrocellulose membrane such as printing resolution, protein immobilization, and sample purification capabilities were also characterized in this report. We believe the wax-patterned nitrocellulose membrane will enhance the capabilities of paper microfluidic devices and bring new applications in this field.
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abstractPaper-based microfluidics is a promising technology to develop a simple, low-cost, portable, and disposable diagnostic platform for resource-limited settings. Here we report the fabrication of paper-based microfluidic devices in nitrocellulose membrane by wax printing for protein immobilization related applications. The fabrication process, which can be finished within 10 min, includes mainly printing and baking steps. Wax patterning will form hydrophobic regions in the membrane, which can be used to direct the flow path or separate reaction zones. The fabrication parameters like printing mode and baking time were optimized, and performances of the wax-patterned nitrocellulose membrane such as printing resolution, protein immobilization, and sample purification capabilities were also characterized in this report. We believe the wax-patterned nitrocellulose membrane will enhance the capabilities of paper microfluidic devices and bring new applications in this field.
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