schliessen

Filtern

 

Bibliotheken

Genotypic characterization and in vitro activities of tigecycline and polymyxin B for members of the Enterobacteriaceae with decreased susceptibility to carbapenems

Carbapenem resistance in members of the Enterobacteriaceae is increasing. To evaluate the effects of tigecycline and polymyxin B against carbapenem-non-susceptible pathogens, 89 representative clinical carbapenem-non-susceptible Enterobacteriaceae isolates were recovered from seven hospitals from fo... Full description

Journal Title: Journal of medical microbiology December 2011, Vol.60(Pt 12), pp.1813-9
Main Author: Zhang, Rong
Other Authors: Cai, Jia-Chang , Zhou, Hong-Wei , Nasu, Masao , Chen, Gong-Xiang
Format: Electronic Article Electronic Article
Language: English
Subjects:
ID: E-ISSN: 1473-5644 ; PMID: 21835972 Version:1 ; DOI: 10.1099/jmm.0.025668-0
Link: http://pubmed.gov/21835972
Zum Text:
SendSend as email Add to Book BagAdd to Book Bag
Staff View
recordid: medline21835972
title: Genotypic characterization and in vitro activities of tigecycline and polymyxin B for members of the Enterobacteriaceae with decreased susceptibility to carbapenems
format: Article
creator:
  • Zhang, Rong
  • Cai, Jia-Chang
  • Zhou, Hong-Wei
  • Nasu, Masao
  • Chen, Gong-Xiang
subjects:
  • Anti-Bacterial Agents -- Pharmacology
  • Carbapenems -- Pharmacology
  • Enterobacteriaceae -- Drug Effects
  • Minocycline -- Analogs & Derivatives
  • Polymyxin B -- Pharmacology
ispartof: Journal of medical microbiology, December 2011, Vol.60(Pt 12), pp.1813-9
description: Carbapenem resistance in members of the Enterobacteriaceae is increasing. To evaluate the effects of tigecycline and polymyxin B against carbapenem-non-susceptible pathogens, 89 representative clinical carbapenem-non-susceptible Enterobacteriaceae isolates were recovered from seven hospitals from four cities in China during 2006-2009: 30 Serratia marcescens, 35 Klebsiella pneumoniae, seven Enterobacter cloacae, six Enterobacter aerogenes, five Escherichia coli, four Citrobacter freundii and two Klebsiella oxytoca isolates. Twenty-eight S. marcescens isolates were indistinguishable. The 35 K. pneumoniae isolates belonged to 12 clonal strains. Among the 89 Enterobacteriaceae isolates, 82 produced KPC-2, seven produced IMP (three produced KPC-2 simultaneously), three did not produce any carbapenemases and nine were deficient in porins. Polymyxin B was much more active than tigecycline against carbapenem-non-susceptible Enterobacteriaceae. The MIC(50) and MIC(90) of imipenem, meropenem, ertapenem,...
language: eng
source:
identifier: E-ISSN: 1473-5644 ; PMID: 21835972 Version:1 ; DOI: 10.1099/jmm.0.025668-0
fulltext: fulltext
issn:
  • 14735644
  • 1473-5644
url: Link


@attributes
ID1730840298
RANK0.07
NO1
SEARCH_ENGINEprimo_central_multiple_fe
SEARCH_ENGINE_TYPEPrimo Central Search Engine
LOCALfalse
PrimoNMBib
record
control
sourcerecordid21835972
sourceidmedline
recordidTN_medline21835972
sourceformatXML
sourcesystemPC
pqid918061362
display
typearticle
titleGenotypic characterization and in vitro activities of tigecycline and polymyxin B for members of the Enterobacteriaceae with decreased susceptibility to carbapenems
creatorZhang, Rong ; Cai, Jia-Chang ; Zhou, Hong-Wei ; Nasu, Masao ; Chen, Gong-Xiang
ispartofJournal of medical microbiology, December 2011, Vol.60(Pt 12), pp.1813-9
identifier
subjectAnti-Bacterial Agents -- Pharmacology ; Carbapenems -- Pharmacology ; Enterobacteriaceae -- Drug Effects ; Minocycline -- Analogs & Derivatives ; Polymyxin B -- Pharmacology
descriptionCarbapenem resistance in members of the Enterobacteriaceae is increasing. To evaluate the effects of tigecycline and polymyxin B against carbapenem-non-susceptible pathogens, 89 representative clinical carbapenem-non-susceptible Enterobacteriaceae isolates were recovered from seven hospitals from four cities in China during 2006-2009: 30 Serratia marcescens, 35 Klebsiella pneumoniae, seven Enterobacter cloacae, six Enterobacter aerogenes, five Escherichia coli, four Citrobacter freundii and two Klebsiella oxytoca isolates. Twenty-eight S. marcescens isolates were indistinguishable. The 35 K. pneumoniae isolates belonged to 12 clonal strains. Among the 89 Enterobacteriaceae isolates, 82 produced KPC-2, seven produced IMP (three produced KPC-2 simultaneously), three did not produce any carbapenemases and nine were deficient in porins. Polymyxin B was much more active than tigecycline against carbapenem-non-susceptible Enterobacteriaceae. The MIC(50) and MIC(90) of imipenem, meropenem, ertapenem,...
languageeng
source
version4
lds50peer_reviewed
links
openurl$$Topenurl_article
backlink$$Uhttp://pubmed.gov/21835972$$EView_this_record_in_MEDLINE/PubMed
openurlfulltext$$Topenurlfull_article
addlink$$Uhttp://exlibris-pub.s3.amazonaws.com/aboutMedline.html$$EView_the_MEDLINE/PubMed_Copyright_Statement
search
creatorcontrib
0Zhang, Rong
1Cai, Jia-Chang
2Zhou, Hong-Wei
3Nasu, Masao
4Chen, Gong-Xiang
titleGenotypic characterization and in vitro activities of tigecycline and polymyxin B for members of the Enterobacteriaceae with decreased susceptibility to carbapenems
descriptionCarbapenem resistance in members of the Enterobacteriaceae is increasing. To evaluate the effects of tigecycline and polymyxin B against carbapenem-non-susceptible pathogens, 89 representative clinical carbapenem-non-susceptible Enterobacteriaceae isolates were recovered from seven hospitals from four cities in China during 2006-2009: 30 Serratia marcescens, 35 Klebsiella pneumoniae, seven Enterobacter cloacae, six Enterobacter aerogenes, five Escherichia coli, four Citrobacter freundii and two Klebsiella oxytoca isolates. Twenty-eight S. marcescens isolates were indistinguishable. The 35 K. pneumoniae isolates belonged to 12 clonal strains. Among the 89 Enterobacteriaceae isolates, 82 produced KPC-2, seven produced IMP (three produced KPC-2 simultaneously), three did not produce any carbapenemases and nine were deficient in porins. Polymyxin B was much more active than tigecycline against carbapenem-non-susceptible Enterobacteriaceae. The MIC(50) and MIC(90) of imipenem, meropenem, ertapenem,...
subject
0Anti-Bacterial Agents -- Pharmacology
1Carbapenems -- Pharmacology
2Enterobacteriaceae -- Drug Effects
3Minocycline -- Analogs & Derivatives
4Polymyxin B -- Pharmacology
general
021835972
1English
2MEDLINE/PubMed (U.S. National Library of Medicine)
310.1099/jmm.0.025668-0
4MEDLINE/PubMed (NLM)
sourceidmedline
recordidmedline21835972
issn
014735644
11473-5644
rsrctypearticle
creationdate2011
addtitleJournal of medical microbiology
searchscope
0medline
1nlm_medline
2MEDLINE
scope
0medline
1nlm_medline
2MEDLINE
lsr41201112
citationpf 1813 vol 60 issue Pt 12
startdate20111201
enddate20111231
lsr30VSR-Enriched:[pqid, issue, pages]
sort
titleGenotypic characterization and in vitro activities of tigecycline and polymyxin B for members of the Enterobacteriaceae with decreased susceptibility to carbapenems
authorZhang, Rong ; Cai, Jia-Chang ; Zhou, Hong-Wei ; Nasu, Masao ; Chen, Gong-Xiang
creationdate20111200
lso0120111200
facets
frbrgroupid5530868607941033211
frbrtype5
newrecords20190701
languageeng
creationdate2011
topic
0Anti-Bacterial Agents–Pharmacology
1Carbapenems–Pharmacology
2Enterobacteriaceae–Drug Effects
3Minocycline–Analogs & Derivatives
4Polymyxin B–Pharmacology
collectionMEDLINE/PubMed (NLM)
prefilterarticles
rsrctypearticles
creatorcontrib
0Zhang, Rong
1Cai, Jia-Chang
2Zhou, Hong-Wei
3Nasu, Masao
4Chen, Gong-Xiang
jtitleJournal Of Medical Microbiology
toplevelpeer_reviewed
delivery
delcategoryRemote Search Resource
fulltextfulltext
addata
aulast
0Zhang
1Cai
2Zhou
3Nasu
4Chen
aufirst
0Rong
1Jia-Chang
2Hong-Wei
3Masao
4Gong-Xiang
au
0Zhang, Rong
1Cai, Jia-Chang
2Zhou, Hong-Wei
3Nasu, Masao
4Chen, Gong-Xiang
atitleGenotypic characterization and in vitro activities of tigecycline and polymyxin B for members of the Enterobacteriaceae with decreased susceptibility to carbapenems
jtitleJournal of medical microbiology
risdate201112
volume60
issue12
spage1813
pages1813-1819
issn0022-2615
eissn1473-5644
formatjournal
genrearticle
ristypeJOUR
abstractCarbapenem resistance in members of the Enterobacteriaceae is increasing. To evaluate the effects of tigecycline and polymyxin B against carbapenem-non-susceptible pathogens, 89 representative clinical carbapenem-non-susceptible Enterobacteriaceae isolates were recovered from seven hospitals from four cities in China during 2006-2009: 30 Serratia marcescens, 35 Klebsiella pneumoniae, seven Enterobacter cloacae, six Enterobacter aerogenes, five Escherichia coli, four Citrobacter freundii and two Klebsiella oxytoca isolates. Twenty-eight S. marcescens isolates were indistinguishable. The 35 K. pneumoniae isolates belonged to 12 clonal strains. Among the 89 Enterobacteriaceae isolates, 82 produced KPC-2, seven produced IMP (three produced KPC-2 simultaneously), three did not produce any carbapenemases and nine were deficient in porins. Polymyxin B was much more active than tigecycline against carbapenem-non-susceptible Enterobacteriaceae. The MIC(50) and MIC(90) of imipenem, meropenem, ertapenem,...
doi10.1099/jmm.0.025668-0
pmid21835972
date2011-12