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Use of dual X-ray absorptiometry to measure body mass during short- to medium-term trials of nutrition and exercise interventions

Dual X-ray absorptiometry (DXA) has a range of clinical applications, from assessing associations between adipose or lean body mass and the risk of disease to measuring the effects of dietary interventions on adipose deposition and oxidation and/or muscle accumulation. Many lifestyle-related studies... Full description

Journal Title: Nutrition reviews June 2013, Vol.71(6), pp.332-42
Main Author: Marinangeli, Christopher P F
Other Authors: Kassis, Amira N
Format: Electronic Article Electronic Article
Language: English
Subjects:
ID: E-ISSN: 1753-4887 ; PMID: 23731444 Version:1 ; DOI: 10.1111/nure.12025
Link: http://pubmed.gov/23731444
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recordid: medline23731444
title: Use of dual X-ray absorptiometry to measure body mass during short- to medium-term trials of nutrition and exercise interventions
format: Article
creator:
  • Marinangeli, Christopher P F
  • Kassis, Amira N
subjects:
  • Absorptiometry, Photon -- Methods
  • Body Composition -- Physiology
ispartof: Nutrition reviews, June 2013, Vol.71(6), pp.332-42
description: Dual X-ray absorptiometry (DXA) has a range of clinical applications, from assessing associations between adipose or lean body mass and the risk of disease to measuring the effects of dietary interventions on adipose deposition and oxidation and/or muscle accumulation. Many lifestyle-related studies, however, are short- to medium-term interventions, and inter- or intradevice variation between DXA scanners can facilitate type I and type II errors during data analysis. Studies demonstrate that variation in body composition measurements exist not only between DXA instruments using fan-beam and pencil-beam technologies but also between DXA instruments produced by different manufacturers. Moreover, studies show inter- and intrainstrument variation between identical DXA instruments. Such inter- and intrascan variability between instruments can be compounded by the particular patient population being investigated. The objective of this review is to discuss inter- and intradevice variation of DXA instruments and to outline quality control procedures that should be implemented prior to initiating short-term single or multicenter clinical trials that use DXA to investigate the effects of an intervention on loss or accretion of lean or fat mass.
language: eng
source:
identifier: E-ISSN: 1753-4887 ; PMID: 23731444 Version:1 ; DOI: 10.1111/nure.12025
fulltext: fulltext
issn:
  • 17534887
  • 1753-4887
url: Link


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titleUse of dual X-ray absorptiometry to measure body mass during short- to medium-term trials of nutrition and exercise interventions
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descriptionDual X-ray absorptiometry (DXA) has a range of clinical applications, from assessing associations between adipose or lean body mass and the risk of disease to measuring the effects of dietary interventions on adipose deposition and oxidation and/or muscle accumulation. Many lifestyle-related studies, however, are short- to medium-term interventions, and inter- or intradevice variation between DXA scanners can facilitate type I and type II errors during data analysis. Studies demonstrate that variation in body composition measurements exist not only between DXA instruments using fan-beam and pencil-beam technologies but also between DXA instruments produced by different manufacturers. Moreover, studies show inter- and intrainstrument variation between identical DXA instruments. Such inter- and intrascan variability between instruments can be compounded by the particular patient population being investigated. The objective of this review is to discuss inter- and intradevice variation of DXA instruments and to outline quality control procedures that should be implemented prior to initiating short-term single or multicenter clinical trials that use DXA to investigate the effects of an intervention on loss or accretion of lean or fat mass.
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abstractDual X-ray absorptiometry (DXA) has a range of clinical applications, from assessing associations between adipose or lean body mass and the risk of disease to measuring the effects of dietary interventions on adipose deposition and oxidation and/or muscle accumulation. Many lifestyle-related studies, however, are short- to medium-term interventions, and inter- or intradevice variation between DXA scanners can facilitate type I and type II errors during data analysis. Studies demonstrate that variation in body composition measurements exist not only between DXA instruments using fan-beam and pencil-beam technologies but also between DXA instruments produced by different manufacturers. Moreover, studies show inter- and intrainstrument variation between identical DXA instruments. Such inter- and intrascan variability between instruments can be compounded by the particular patient population being investigated. The objective of this review is to discuss inter- and intradevice variation of DXA instruments and to outline quality control procedures that should be implemented prior to initiating short-term single or multicenter clinical trials that use DXA to investigate the effects of an intervention on loss or accretion of lean or fat mass.
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