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Mediterranean diet reduces 24-hour ambulatory blood pressure, blood glucose, and lipids: one-year randomized, clinical trial

The PREvención con DIeta MEDiterránea (PREDIMED) trial showed that Mediterranean diets (MedDiets) supplemented with either extravirgin olive oil or nuts reduced cardiovascular events, particularly stroke, compared with a control, lower fat diet. The mechanisms of cardiovascular protection remain unc... Full description

Journal Title: Hypertension (Dallas Tex. : 1979), July 2014, Vol.64(1), pp.69-76
Main Author: Doménech, Mónica
Other Authors: Roman, Pilar , Lapetra, José , García De La Corte, Francisco J , Sala-Vila, Aleix , De La Torre, Rafael , Corella, Dolores , Salas-Salvadó, Jordi , Ruiz-Gutiérrez, Valentina , Lamuela-Raventós, Rosa-María , Toledo, Estefania , Estruch
Format: Electronic Article Electronic Article
Language: English
Subjects:
ID: E-ISSN: 1524-4563 ; PMID: 24799608 Version:1 ; DOI: 10.1161/HYPERTENSIONAHA.113.03353
Link: http://pubmed.gov/24799608
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recordid: medline24799608
title: Mediterranean diet reduces 24-hour ambulatory blood pressure, blood glucose, and lipids: one-year randomized, clinical trial
format: Article
creator:
  • Doménech, Mónica
  • Roman, Pilar
  • Lapetra, José
  • García De La Corte, Francisco J
  • Sala-Vila, Aleix
  • De La Torre, Rafael
  • Corella, Dolores
  • Salas-Salvadó, Jordi
  • Ruiz-Gutiérrez, Valentina
  • Lamuela-Raventós, Rosa-María
  • Toledo, Estefania
  • Estruch
subjects:
  • Blood Pressure
  • Clinical Trials, Randomized
  • Diet, Mediterranean
  • Nuts
  • Olive Oil
  • Diet, Mediterranean
  • Blood Glucose -- Metabolism
  • Blood Pressure -- Physiology
  • Cardiovascular Diseases -- Prevention & Control
  • Lipids -- Blood
ispartof: Hypertension (Dallas, Tex. : 1979), July 2014, Vol.64(1), pp.69-76
description: The PREvención con DIeta MEDiterránea (PREDIMED) trial showed that Mediterranean diets (MedDiets) supplemented with either extravirgin olive oil or nuts reduced cardiovascular events, particularly stroke, compared with a control, lower fat diet. The mechanisms of cardiovascular protection remain unclear. We evaluated the 1-year effects of supplemented MedDiets on 24-hour ambulatory blood pressure (BP), blood glucose, and lipids. Randomized, parallel-design, controlled trial was conducted in 2 PREDIMED sites. Diets were ad libitum, and no advice on increasing physical activity or reducing sodium intake was given. Participants were 235 subjects (56.5% women; mean age, 66.5 years) at high cardiovascular risk (85.4% with hypertension). Adjusted changes from baseline in mean systolic BP were -2.3 (95% confidence interval [CI], -4.0 to -0.5) mm Hg and -2.6 (95% CI, -4.3 to -0.9) mm Hg in the MedDiets with olive oil and the MedDiets with nuts, respectively, and 1.7 (95% CI, -0.1 to 3.5) mm Hg... http://www.clinicaltrials.gov. Unique identifier: ISRCTN35739639.
language: eng
source:
identifier: E-ISSN: 1524-4563 ; PMID: 24799608 Version:1 ; DOI: 10.1161/HYPERTENSIONAHA.113.03353
fulltext: fulltext
issn:
  • 15244563
  • 1524-4563
url: Link


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titleMediterranean diet reduces 24-hour ambulatory blood pressure, blood glucose, and lipids: one-year randomized, clinical trial
creatorDoménech, Mónica ; Roman, Pilar ; Lapetra, José ; García De La Corte, Francisco J ; Sala-Vila, Aleix ; De La Torre, Rafael ; Corella, Dolores ; Salas-Salvadó, Jordi ; Ruiz-Gutiérrez, Valentina ; Lamuela-Raventós, Rosa-María ; Toledo, Estefania ; Estruch
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subjectBlood Pressure ; Clinical Trials, Randomized ; Diet, Mediterranean ; Nuts ; Olive Oil ; Diet, Mediterranean ; Blood Glucose -- Metabolism ; Blood Pressure -- Physiology ; Cardiovascular Diseases -- Prevention & Control ; Lipids -- Blood
descriptionThe PREvención con DIeta MEDiterránea (PREDIMED) trial showed that Mediterranean diets (MedDiets) supplemented with either extravirgin olive oil or nuts reduced cardiovascular events, particularly stroke, compared with a control, lower fat diet. The mechanisms of cardiovascular protection remain unclear. We evaluated the 1-year effects of supplemented MedDiets on 24-hour ambulatory blood pressure (BP), blood glucose, and lipids. Randomized, parallel-design, controlled trial was conducted in 2 PREDIMED sites. Diets were ad libitum, and no advice on increasing physical activity or reducing sodium intake was given. Participants were 235 subjects (56.5% women; mean age, 66.5 years) at high cardiovascular risk (85.4% with hypertension). Adjusted changes from baseline in mean systolic BP were -2.3 (95% confidence interval [CI], -4.0 to -0.5) mm Hg and -2.6 (95% CI, -4.3 to -0.9) mm Hg in the MedDiets with olive oil and the MedDiets with nuts, respectively, and 1.7 (95% CI, -0.1 to 3.5) mm Hg... http://www.clinicaltrials.gov. Unique identifier: ISRCTN35739639.
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abstractThe PREvención con DIeta MEDiterránea (PREDIMED) trial showed that Mediterranean diets (MedDiets) supplemented with either extravirgin olive oil or nuts reduced cardiovascular events, particularly stroke, compared with a control, lower fat diet. The mechanisms of cardiovascular protection remain unclear. We evaluated the 1-year effects of supplemented MedDiets on 24-hour ambulatory blood pressure (BP), blood glucose, and lipids. Randomized, parallel-design, controlled trial was conducted in 2 PREDIMED sites. Diets were ad libitum, and no advice on increasing physical activity or reducing sodium intake was given. Participants were 235 subjects (56.5% women; mean age, 66.5 years) at high cardiovascular risk (85.4% with hypertension). Adjusted changes from baseline in mean systolic BP were -2.3 (95% confidence interval [CI], -4.0 to -0.5) mm Hg and -2.6 (95% CI, -4.3 to -0.9) mm Hg in the MedDiets with olive oil and the MedDiets with nuts, respectively, and 1.7 (95% CI, -0.1 to 3.5) mm Hg...
doi10.1161/HYPERTENSIONAHA.113.03353
pmid24799608
date2014-07