schliessen

Filtern

 

Bibliotheken

Quality control for building libraries from electrospray ionization tandem mass spectra

Electrospray ionization (ESI) tandem mass spectrometry coupled with liquid chromatography is a routine technique for identifying and quantifying compounds in complex mixtures. The identification step can be aided by matching acquired tandem mass spectra (MS(2)) against reference library spectra as i... Full description

Journal Title: Analytical chemistry 01 July 2014, Vol.86(13), pp.6393-400
Main Author: Yang, Xiaoyu
Other Authors: Neta, Pedatsur , Stein, Stephen E
Format: Electronic Article Electronic Article
Language: English
Subjects:
ID: E-ISSN: 1520-6882 ; PMID: 24896981 Version:1 ; DOI: 10.1021/ac500711m
Link: http://pubmed.gov/24896981
Zum Text:
SendSend as email Add to Book BagAdd to Book Bag
Staff View
recordid: medline24896981
title: Quality control for building libraries from electrospray ionization tandem mass spectra
format: Article
creator:
  • Yang, Xiaoyu
  • Neta, Pedatsur
  • Stein, Stephen E
subjects:
  • Engineering
  • Chemistry
ispartof: Analytical chemistry, 01 July 2014, Vol.86(13), pp.6393-400
description: Electrospray ionization (ESI) tandem mass spectrometry coupled with liquid chromatography is a routine technique for identifying and quantifying compounds in complex mixtures. The identification step can be aided by matching acquired tandem mass spectra (MS(2)) against reference library spectra as is routine for electron ionization (EI) spectra from gas chromatography/mass spectrometry (GC/MS). However, unlike the latter spectra, ESI MS(2) spectra are likely to originate from various precursor ions for a given target molecule and may be acquired at varying energies and resolutions and have characteristic noise signatures, requiring processing methods very different from EI to obtain complete and high quality reference spectra for individual analytes. This paper presents procedures developed for creating a tandem mass spectral library that addresses these factors. Library building begins by acquiring MS(2) spectra for all major MS(1) peaks in an infusion run, followed by assigning MS(2)...
language: eng
source:
identifier: E-ISSN: 1520-6882 ; PMID: 24896981 Version:1 ; DOI: 10.1021/ac500711m
fulltext: fulltext
issn:
  • 15206882
  • 1520-6882
url: Link


@attributes
ID1683980757
RANK0.07
NO1
SEARCH_ENGINEprimo_central_multiple_fe
SEARCH_ENGINE_TYPEPrimo Central Search Engine
LOCALfalse
PrimoNMBib
record
control
sourcerecordid24896981
sourceidmedline
recordidTN_medline24896981
sourceformatXML
sourcesystemPC
pqid1542300427
display
typearticle
titleQuality control for building libraries from electrospray ionization tandem mass spectra
creatorYang, Xiaoyu ; Neta, Pedatsur ; Stein, Stephen E
ispartofAnalytical chemistry, 01 July 2014, Vol.86(13), pp.6393-400
identifier
descriptionElectrospray ionization (ESI) tandem mass spectrometry coupled with liquid chromatography is a routine technique for identifying and quantifying compounds in complex mixtures. The identification step can be aided by matching acquired tandem mass spectra (MS(2)) against reference library spectra as is routine for electron ionization (EI) spectra from gas chromatography/mass spectrometry (GC/MS). However, unlike the latter spectra, ESI MS(2) spectra are likely to originate from various precursor ions for a given target molecule and may be acquired at varying energies and resolutions and have characteristic noise signatures, requiring processing methods very different from EI to obtain complete and high quality reference spectra for individual analytes. This paper presents procedures developed for creating a tandem mass spectral library that addresses these factors. Library building begins by acquiring MS(2) spectra for all major MS(1) peaks in an infusion run, followed by assigning MS(2)...
languageeng
source
subjectEngineering ; Chemistry;
version5
lds50peer_reviewed
links
openurl$$Topenurl_article
backlink$$Uhttp://pubmed.gov/24896981$$EView_this_record_in_MEDLINE/PubMed
openurlfulltext$$Topenurlfull_article
addlink$$Uhttp://exlibris-pub.s3.amazonaws.com/aboutMedline.html$$EView_the_MEDLINE/PubMed_Copyright_Statement
search
creatorcontrib
0Yang, Xiaoyu
1Neta, Pedatsur
2Stein, Stephen E
titleQuality control for building libraries from electrospray ionization tandem mass spectra
descriptionElectrospray ionization (ESI) tandem mass spectrometry coupled with liquid chromatography is a routine technique for identifying and quantifying compounds in complex mixtures. The identification step can be aided by matching acquired tandem mass spectra (MS(2)) against reference library spectra as is routine for electron ionization (EI) spectra from gas chromatography/mass spectrometry (GC/MS). However, unlike the latter spectra, ESI MS(2) spectra are likely to originate from various precursor ions for a given target molecule and may be acquired at varying energies and resolutions and have characteristic noise signatures, requiring processing methods very different from EI to obtain complete and high quality reference spectra for individual analytes. This paper presents procedures developed for creating a tandem mass spectral library that addresses these factors. Library building begins by acquiring MS(2) spectra for all major MS(1) peaks in an infusion run, followed by assigning MS(2)...
general
024896981
1English
2MEDLINE/PubMed (U.S. National Library of Medicine)
310.1021/ac500711m
4MEDLINE/PubMed (NLM)
sourceidmedline
recordidmedline24896981
issn
015206882
11520-6882
rsrctypearticle
creationdate2014
addtitleAnalytical chemistry
searchscope
0medline
1nlm_medline
2MEDLINE
scope
0medline
1nlm_medline
2MEDLINE
lsr4120140701
citationpf 6393 vol 86 issue 13
startdate20140701
enddate20140701
lsr30VSR-Enriched:[pqid, subject, pages]
sort
titleQuality control for building libraries from electrospray ionization tandem mass spectra
authorYang, Xiaoyu ; Neta, Pedatsur ; Stein, Stephen E
creationdate20140701
lso0120140701
facets
frbrgroupid7794649981692149976
frbrtype5
newrecords20190701
languageeng
creationdate2014
collectionMEDLINE/PubMed (NLM)
prefilterarticles
rsrctypearticles
creatorcontrib
0Yang, Xiaoyu
1Neta, Pedatsur
2Stein, Stephen E
jtitleAnalytical Chemistry
toplevelpeer_reviewed
delivery
delcategoryRemote Search Resource
fulltextfulltext
addata
aulast
0Yang
1Neta
2Stein
aufirst
0Xiaoyu
1Pedatsur
2Stephen E
au
0Yang, Xiaoyu
1Neta, Pedatsur
2Stein, Stephen E
atitleQuality control for building libraries from electrospray ionization tandem mass spectra
jtitleAnalytical chemistry
risdate20140701
volume86
issue13
spage6393
pages6393-6400
issn0003-2700
eissn1520-6882
formatjournal
genrearticle
ristypeJOUR
abstractElectrospray ionization (ESI) tandem mass spectrometry coupled with liquid chromatography is a routine technique for identifying and quantifying compounds in complex mixtures. The identification step can be aided by matching acquired tandem mass spectra (MS(2)) against reference library spectra as is routine for electron ionization (EI) spectra from gas chromatography/mass spectrometry (GC/MS). However, unlike the latter spectra, ESI MS(2) spectra are likely to originate from various precursor ions for a given target molecule and may be acquired at varying energies and resolutions and have characteristic noise signatures, requiring processing methods very different from EI to obtain complete and high quality reference spectra for individual analytes. This paper presents procedures developed for creating a tandem mass spectral library that addresses these factors. Library building begins by acquiring MS(2) spectra for all major MS(1) peaks in an infusion run, followed by assigning MS(2)...
doi10.1021/ac500711m
pmid24896981
date2014-07-01