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Antipyretic potential of herbal coded formulation (Pyrexol)

The antipyretic effect of the aqueous extract of herbal coded formulation containing equal amount of Salix alba, Emblica officinalis, Glycyrrhiza glabra, Adhatoda vasica, Viola odorata, Thea sinensis, Veleriana officinalis, Foeniculum vulgare, Sisymbrium irrio and Achillea millefolium was investigat... Full description

Journal Title: Pakistan journal of pharmaceutical sciences January 2017, Vol.30(1), pp.195-198
Main Author: Khan, Muhammad Sajid
Other Authors: Hamid, Abdul , Akram, Muhammad , Mustafa, Sodah Bint , Sami, Abdul , Shah, Syed Muhammad Ali , Usmanghani, Khan
Format: Electronic Article Electronic Article
Language: English
Subjects:
ID: ISSN: 1011-601X ; PMID: 28603131 Version:1
Link: http://pubmed.gov/28603131
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recordid: medline28603131
title: Antipyretic potential of herbal coded formulation (Pyrexol)
format: Article
creator:
  • Khan, Muhammad Sajid
  • Hamid, Abdul
  • Akram, Muhammad
  • Mustafa, Sodah Bint
  • Sami, Abdul
  • Shah, Syed Muhammad Ali
  • Usmanghani, Khan
subjects:
  • Antipyretics -- Pharmacology
  • Body Temperature Regulation -- Drug Effects
  • Fever -- Prevention & Control
  • Plant Extracts -- Pharmacology
ispartof: Pakistan journal of pharmaceutical sciences, January 2017, Vol.30(1), pp.195-198
description: The antipyretic effect of the aqueous extract of herbal coded formulation containing equal amount of Salix alba, Emblica officinalis, Glycyrrhiza glabra, Adhatoda vasica, Viola odorata, Thea sinensis, Veleriana officinalis, Foeniculum vulgare, Sisymbrium irrio and Achillea millefolium was investigated using the yeast induced pyrexia model in rabbits. Paracetamol was used as a control group. Rectal temperatures of all rabbits were recorded immediately before the administration of the extract or paracetamol and again at 1 hour, after this, temperature was noted at 1 hrs interval for 5 hrs using digital thermometer. At 240mg/kg dose the extract showed significant reduction in yeast-induced elevated temperature as compared with that of standard drug paracetamol (150mg/kg). It is concluded that herbal coded medicine at a dose of 240mg/kg has marked antipyretic activity in animal models and this strongly supports the ethno pharmacological uses of medicinal plants of this formulation.
language: eng
source:
identifier: ISSN: 1011-601X ; PMID: 28603131 Version:1
fulltext: fulltext
issn:
  • 1011601X
  • 1011-601X
url: Link


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titleAntipyretic potential of herbal coded formulation (Pyrexol)
creatorKhan, Muhammad Sajid ; Hamid, Abdul ; Akram, Muhammad ; Mustafa, Sodah Bint ; Sami, Abdul ; Shah, Syed Muhammad Ali ; Usmanghani, Khan
ispartofPakistan journal of pharmaceutical sciences, January 2017, Vol.30(1), pp.195-198
identifierISSN: 1011-601X ; PMID: 28603131 Version:1
subjectAntipyretics -- Pharmacology ; Body Temperature Regulation -- Drug Effects ; Fever -- Prevention & Control ; Plant Extracts -- Pharmacology
descriptionThe antipyretic effect of the aqueous extract of herbal coded formulation containing equal amount of Salix alba, Emblica officinalis, Glycyrrhiza glabra, Adhatoda vasica, Viola odorata, Thea sinensis, Veleriana officinalis, Foeniculum vulgare, Sisymbrium irrio and Achillea millefolium was investigated using the yeast induced pyrexia model in rabbits. Paracetamol was used as a control group. Rectal temperatures of all rabbits were recorded immediately before the administration of the extract or paracetamol and again at 1 hour, after this, temperature was noted at 1 hrs interval for 5 hrs using digital thermometer. At 240mg/kg dose the extract showed significant reduction in yeast-induced elevated temperature as compared with that of standard drug paracetamol (150mg/kg). It is concluded that herbal coded medicine at a dose of 240mg/kg has marked antipyretic activity in animal models and this strongly supports the ethno pharmacological uses of medicinal plants of this formulation.
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titleAntipyretic potential of herbal coded formulation (Pyrexol)
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abstractThe antipyretic effect of the aqueous extract of herbal coded formulation containing equal amount of Salix alba, Emblica officinalis, Glycyrrhiza glabra, Adhatoda vasica, Viola odorata, Thea sinensis, Veleriana officinalis, Foeniculum vulgare, Sisymbrium irrio and Achillea millefolium was investigated using the yeast induced pyrexia model in rabbits. Paracetamol was used as a control group. Rectal temperatures of all rabbits were recorded immediately before the administration of the extract or paracetamol and again at 1 hour, after this, temperature was noted at 1 hrs interval for 5 hrs using digital thermometer. At 240mg/kg dose the extract showed significant reduction in yeast-induced elevated temperature as compared with that of standard drug paracetamol (150mg/kg). It is concluded that herbal coded medicine at a dose of 240mg/kg has marked antipyretic activity in animal models and this strongly supports the ethno pharmacological uses of medicinal plants of this formulation.
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