schliessen

Filtern

 

Bibliotheken

Fetal and Infant Growth Patterns and Risk of Lower Lung Function and Asthma. The Generation R Study

Children with lower birth weight are at increased risk of asthma symptoms. To examine associations of fetal and infant growth with childhood lung function and asthma. This study was embedded in a population-based prospective cohort study of 5,635 children. Growth was estimated by repeated ultrasound... Full description

Journal Title: American journal of respiratory and critical care medicine 15 January 2018, Vol.197(2), pp.183-192
Main Author: Den Dekker, Herman T
Other Authors: Jaddoe, Vincent W V , Reiss, Irwin K , De Jongste, Johan C , Duijts, Liesbeth
Format: Electronic Article Electronic Article
Language: English
Subjects:
ID: E-ISSN: 1535-4970 ; PMID: 28930491 Version:1 ; DOI: 10.1164/rccm.201703-0631OC
Link: http://pubmed.gov/28930491
Zum Text:
SendSend as email Add to Book BagAdd to Book Bag
Staff View
recordid: medline28930491
title: Fetal and Infant Growth Patterns and Risk of Lower Lung Function and Asthma. The Generation R Study
format: Article
creator:
  • Den Dekker, Herman T
  • Jaddoe, Vincent W V
  • Reiss, Irwin K
  • De Jongste, Johan C
  • Duijts, Liesbeth
subjects:
  • Asthma
  • Fetal Growth
  • Infant Growth
  • Lung Function
  • Spirometry
  • Asthma -- Diagnosis
  • Child Development -- Physiology
  • Infant, Low Birth Weight -- Growth & Development
  • Lung -- Physiopathology
ispartof: American journal of respiratory and critical care medicine, 15 January 2018, Vol.197(2), pp.183-192
description: Children with lower birth weight are at increased risk of asthma symptoms. To examine associations of fetal and infant growth with childhood lung function and asthma. This study was embedded in a population-based prospective cohort study of 5,635 children. Growth was estimated by repeated ultrasounds in the second and third trimesters, and measured at birth and at 3, 6, and 12 months. At age 10 years, spirometry was performed and asthma was assessed by parental questionnaire. Restricted and accelerated growth were defined as the growth percentile change between time periods less than -0.67 and more than 0.67 SD scores (SDSs), respectively. We applied multiple regression analyses, including conditional regression analyses, to account for correlations between repeated growth measures. Overall greater weight in the second and third trimesters, at birth, and at 12 months was associated with higher FEV and FVC (range of z-score difference, 0.04-0.08, per SDS increase in weight). Greater weight at 3 months was associated with lower FEV/FVC and forced expiratory flow at 75% of the pulmonary volume (FEF) (z-score differences [95% confidence interval]: -0.09 [-0.14 to -0.05] and -0.09 [-0.13 to -0.05] per SDS increase in weight, respectively). Restricted fetal weight growth was associated with lower childhood lung-function measures, partly depending on infant weight growth patterns (range of z-score difference, -0.25 to -0.13). Accelerated fetal weight growth was associated with higher FVC and lower FEV/FVC only if followed by accelerated infant weight growth. Fetal and infant weight growth was not associated with childhood asthma. Both restricted fetal weight growth, partly depending on infant weight growth, and accelerated fetal and infant weight growth predispose children to lower lung function and a potential risk for respiratory diseases later in life.
language: eng
source:
identifier: E-ISSN: 1535-4970 ; PMID: 28930491 Version:1 ; DOI: 10.1164/rccm.201703-0631OC
fulltext: fulltext
issn:
  • 15354970
  • 1535-4970
url: Link


@attributes
ID520379707
RANK0.07
NO1
SEARCH_ENGINEprimo_central_multiple_fe
SEARCH_ENGINE_TYPEPrimo Central Search Engine
LOCALfalse
PrimoNMBib
record
control
sourcerecordid28930491
sourceidmedline
recordidTN_medline28930491
sourceformatXML
sourcesystemPC
pqid1991893786
display
typearticle
titleFetal and Infant Growth Patterns and Risk of Lower Lung Function and Asthma. The Generation R Study
creatorDen Dekker, Herman T ; Jaddoe, Vincent W V ; Reiss, Irwin K ; De Jongste, Johan C ; Duijts, Liesbeth
ispartofAmerican journal of respiratory and critical care medicine, 15 January 2018, Vol.197(2), pp.183-192
identifier
subjectAsthma ; Fetal Growth ; Infant Growth ; Lung Function ; Spirometry ; Asthma -- Diagnosis ; Child Development -- Physiology ; Infant, Low Birth Weight -- Growth & Development ; Lung -- Physiopathology
descriptionChildren with lower birth weight are at increased risk of asthma symptoms. To examine associations of fetal and infant growth with childhood lung function and asthma. This study was embedded in a population-based prospective cohort study of 5,635 children. Growth was estimated by repeated ultrasounds in the second and third trimesters, and measured at birth and at 3, 6, and 12 months. At age 10 years, spirometry was performed and asthma was assessed by parental questionnaire. Restricted and accelerated growth were defined as the growth percentile change between time periods less than -0.67 and more than 0.67 SD scores (SDSs), respectively. We applied multiple regression analyses, including conditional regression analyses, to account for correlations between repeated growth measures. Overall greater weight in the second and third trimesters, at birth, and at 12 months was associated with higher FEV and FVC (range of z-score difference, 0.04-0.08, per SDS increase in weight). Greater weight at 3 months was associated with lower FEV/FVC and forced expiratory flow at 75% of the pulmonary volume (FEF) (z-score differences [95% confidence interval]: -0.09 [-0.14 to -0.05] and -0.09 [-0.13 to -0.05] per SDS increase in weight, respectively). Restricted fetal weight growth was associated with lower childhood lung-function measures, partly depending on infant weight growth patterns (range of z-score difference, -0.25 to -0.13). Accelerated fetal weight growth was associated with higher FVC and lower FEV/FVC only if followed by accelerated infant weight growth. Fetal and infant weight growth was not associated with childhood asthma. Both restricted fetal weight growth, partly depending on infant weight growth, and accelerated fetal and infant weight growth predispose children to lower lung function and a potential risk for respiratory diseases later in life.
languageeng
source
version3
lds50peer_reviewed
links
openurl$$Topenurl_article
backlink$$Uhttp://pubmed.gov/28930491$$EView_this_record_in_MEDLINE/PubMed
openurlfulltext$$Topenurlfull_article
addlink$$Uhttp://exlibris-pub.s3.amazonaws.com/aboutMedline.html$$EView_the_MEDLINE/PubMed_Copyright_Statement
search
creatorcontrib
0den Dekker, Herman T
1Jaddoe, Vincent W V
2Reiss, Irwin K
3de Jongste, Johan C
4Duijts, Liesbeth
titleFetal and Infant Growth Patterns and Risk of Lower Lung Function and Asthma. The Generation R Study
description
0Children with lower birth weight are at increased risk of asthma symptoms.
1To examine associations of fetal and infant growth with childhood lung function and asthma.
2This study was embedded in a population-based prospective cohort study of 5,635 children. Growth was estimated by repeated ultrasounds in the second and third trimesters, and measured at birth and at 3, 6, and 12 months. At age 10 years, spirometry was performed and asthma was assessed by parental questionnaire. Restricted and accelerated growth were defined as the growth percentile change between time periods less than -0.67 and more than 0.67 SD scores (SDSs), respectively. We applied multiple regression analyses, including conditional regression analyses, to account for correlations between repeated growth measures.
3Overall greater weight in the second and third trimesters, at birth, and at 12 months was associated with higher FEV and FVC (range of z-score difference, 0.04-0.08, per SDS increase in weight). Greater weight at 3 months was associated with lower FEV/FVC and forced expiratory flow at 75% of the pulmonary volume (FEF) (z-score differences [95% confidence interval]: -0.09 [-0.14 to -0.05] and -0.09 [-0.13 to -0.05] per SDS increase in weight, respectively). Restricted fetal weight growth was associated with lower childhood lung-function measures, partly depending on infant weight growth patterns (range of z-score difference, -0.25 to -0.13). Accelerated fetal weight growth was associated with higher FVC and lower FEV/FVC only if followed by accelerated infant weight growth. Fetal and infant weight growth was not associated with childhood asthma.
4Both restricted fetal weight growth, partly depending on infant weight growth, and accelerated fetal and infant weight growth predispose children to lower lung function and a potential risk for respiratory diseases later in life.
subject
0Asthma
1Fetal Growth
2Infant Growth
3Lung Function
4Spirometry
5Asthma -- Diagnosis
6Child Development -- Physiology
7Infant, Low Birth Weight -- Growth & Development
8Lung -- Physiopathology
general
028930491
1English
2MEDLINE/PubMed (U.S. National Library of Medicine)
310.1164/rccm.201703-0631OC
4MEDLINE/PubMed (NLM)
sourceidmedline
recordidmedline28930491
issn
015354970
11535-4970
rsrctypearticle
creationdate2018
addtitleAmerican journal of respiratory and critical care medicine
searchscope
0medline
1nlm_medline
2MEDLINE
scope
0medline
1nlm_medline
2MEDLINE
lsr41201815
citationpf 183 vol 197 issue 2
startdate20180115
enddate20180115
lsr30VSR-Enriched:[pqid]
sort
titleFetal and Infant Growth Patterns and Risk of Lower Lung Function and Asthma. The Generation R Study
authorDen Dekker, Herman T ; Jaddoe, Vincent W V ; Reiss, Irwin K ; De Jongste, Johan C ; Duijts, Liesbeth
creationdate20180115
lso0120180115
facets
frbrgroupid4011068562565496078
frbrtype5
newrecords20190701
languageeng
creationdate2018
topic
0Asthma
1Fetal Growth
2Infant Growth
3Lung Function
4Spirometry
5Asthma–Diagnosis
6Child Development–Physiology
7Infant, Low Birth Weight–Growth & Development
8Lung–Physiopathology
collectionMEDLINE/PubMed (NLM)
prefilterarticles
rsrctypearticles
creatorcontrib
0Den Dekker, Herman T
1Jaddoe, Vincent W V
2Reiss, Irwin K
3De Jongste, Johan C
4Duijts, Liesbeth
jtitleAmerican Journal Of Respiratory And Critical Care Medicine
toplevelpeer_reviewed
delivery
delcategoryRemote Search Resource
fulltextfulltext
addata
aulast
0Den Dekker
1Jaddoe
2Reiss
3de Jongste
4Duijts
aufirst
0Herman T
1Vincent W V
2Irwin K
3Johan C
4Liesbeth
au
0Den Dekker, Herman T
1Jaddoe, Vincent W V
2Reiss, Irwin K
3de Jongste, Johan C
4Duijts, Liesbeth
atitleFetal and Infant Growth Patterns and Risk of Lower Lung Function and Asthma. The Generation R Study
jtitleAmerican journal of respiratory and critical care medicine
risdate20180115
volume197
issue2
spage183
pages183-192
issn1073-449X
eissn1535-4970
formatjournal
genrearticle
ristypeJOUR
abstractChildren with lower birth weight are at increased risk of asthma symptoms.
doi10.1164/rccm.201703-0631OC
pmid28930491
date2018-01-15