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Organum vasculosum laminae terminalis (OVLT) is a brain site to produce interleukin-1 beta during fever

The present study was carried out to determine whether interleukin-1 (IL-1) production occurs in the rabbit organum vasculosum laminae terminalis (OVLT) during fever induced by endotoxin. The intravenous (i.v.) injection of endotoxin (4 micrograms/kg) caused significant fever in rabbits. Through the... Full description

Journal Title: Brain research 30 July 1993, Vol.618(1), pp.155-9
Main Author: Nakamori, T
Other Authors: Morimoto, A , Yamaguchi, K , Watanabe, T , Long, N C , Murakami, N
Format: Electronic Article Electronic Article
Language: English
Subjects:
ID: ISSN: 0006-8993 ; PMID: 8402169 Version:1
Link: http://pubmed.gov/8402169
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recordid: medline8402169
title: Organum vasculosum laminae terminalis (OVLT) is a brain site to produce interleukin-1 beta during fever
format: Article
creator:
  • Nakamori, T
  • Morimoto, A
  • Yamaguchi, K
  • Watanabe, T
  • Long, N C
  • Murakami, N
subjects:
  • Cerebral Ventricles -- Metabolism
  • Fever -- Metabolism
  • Interleukin-1 -- Biosynthesis
ispartof: Brain research, 30 July 1993, Vol.618(1), pp.155-9
description: The present study was carried out to determine whether interleukin-1 (IL-1) production occurs in the rabbit organum vasculosum laminae terminalis (OVLT) during fever induced by endotoxin. The intravenous (i.v.) injection of endotoxin (4 micrograms/kg) caused significant fever in rabbits. Through the use of in situ hybridization and immunohistochemical techniques, the synthesis of IL-1 was observed in the OVLT during the fever. The present results support the hypothesis that IL-1 is produced in the brain during fever.
language: eng
source:
identifier: ISSN: 0006-8993 ; PMID: 8402169 Version:1
fulltext: fulltext
issn:
  • 00068993
  • 0006-8993
url: Link


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titleOrganum vasculosum laminae terminalis (OVLT) is a brain site to produce interleukin-1 beta during fever
creatorNakamori, T ; Morimoto, A ; Yamaguchi, K ; Watanabe, T ; Long, N C ; Murakami, N
ispartofBrain research, 30 July 1993, Vol.618(1), pp.155-9
identifierISSN: 0006-8993 ; PMID: 8402169 Version:1
subjectCerebral Ventricles -- Metabolism ; Fever -- Metabolism ; Interleukin-1 -- Biosynthesis
descriptionThe present study was carried out to determine whether interleukin-1 (IL-1) production occurs in the rabbit organum vasculosum laminae terminalis (OVLT) during fever induced by endotoxin. The intravenous (i.v.) injection of endotoxin (4 micrograms/kg) caused significant fever in rabbits. Through the use of in situ hybridization and immunohistochemical techniques, the synthesis of IL-1 was observed in the OVLT during the fever. The present results support the hypothesis that IL-1 is produced in the brain during fever.
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titleOrganum vasculosum laminae terminalis (OVLT) is a brain site to produce interleukin-1 beta during fever
descriptionThe present study was carried out to determine whether interleukin-1 (IL-1) production occurs in the rabbit organum vasculosum laminae terminalis (OVLT) during fever induced by endotoxin. The intravenous (i.v.) injection of endotoxin (4 micrograms/kg) caused significant fever in rabbits. Through the use of in situ hybridization and immunohistochemical techniques, the synthesis of IL-1 was observed in the OVLT during the fever. The present results support the hypothesis that IL-1 is produced in the brain during fever.
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titleOrganum vasculosum laminae terminalis (OVLT) is a brain site to produce interleukin-1 beta during fever
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abstractThe present study was carried out to determine whether interleukin-1 (IL-1) production occurs in the rabbit organum vasculosum laminae terminalis (OVLT) during fever induced by endotoxin. The intravenous (i.v.) injection of endotoxin (4 micrograms/kg) caused significant fever in rabbits. Through the use of in situ hybridization and immunohistochemical techniques, the synthesis of IL-1 was observed in the OVLT during the fever. The present results support the hypothesis that IL-1 is produced in the brain during fever.
pmid8402169
doi10.1016/0006-8993(93)90439-T
eissn18726240
date1993-07-30