schliessen

Filtern

 

Bibliotheken

Maternal fish consumption during pregnancy and risks of wheezing and eczema in childhood: The Generation R Study

BACKGROUND/OBJECTIVES: Maternal fish consumption during pregnancy might influence the fetal immune system through anti-inflammatory effects of omega-3 fatty acids, and might affect the risks of childhood asthma and atopy. In Generation R, a prospective cohort study in the Netherlands, we examined th... Full description

Journal Title: European Journal of Clinical Nutrition 2013, Vol.67(4), p.353
Main Author: E T M Leermakers
Other Authors: A M M Sonnenschein-Van Der Voort , D H M Heppe , J C De Jongste , H A Moll , O H Franco , A Hofman , V W V Jaddoe , L Duijts
Format: Electronic Article Electronic Article
Language:
Subjects:
ID: ISSN: 0954-3007 ; E-ISSN: 1476-5640 ; DOI: 10.1038/ejcn.2013.36
Link: http://dx.doi.org/10.1038/ejcn.2013.36
Zum Text:
SendSend as email Add to Book BagAdd to Book Bag
Staff View
recordid: nature_a10.1038/ejcn.2013.36
title: Maternal fish consumption during pregnancy and risks of wheezing and eczema in childhood: The Generation R Study
format: Article
creator:
  • E T M Leermakers
  • A M M Sonnenschein-Van Der Voort
  • D H M Heppe
  • J C De Jongste
  • H A Moll
  • O H Franco
  • A Hofman
  • V W V Jaddoe
  • L Duijts
subjects:
  • Asthma -- Risk Factors
  • Asthma -- Diagnosis
  • Eczema -- Diagnosis
  • Eczema -- Risk Factors
  • Fish (Food Product) -- Health Aspects
  • Mothers -- Health Aspects
  • Pregnant Women -- Health Aspects
  • Wheezing -- Health Aspects
ispartof: European Journal of Clinical Nutrition, 2013, Vol.67(4), p.353
description: BACKGROUND/OBJECTIVES: Maternal fish consumption during pregnancy might influence the fetal immune system through anti-inflammatory effects of omega-3 fatty acids, and might affect the risks of childhood asthma and atopy. In Generation R, a prospective cohort study in the Netherlands, we examined the associations of first trimester fish consumption with childhood wheezing and eczema in the first 4 years of life. METHODS: In total, 2976 mothers completed a 293-item semiquantitative food frequency questionnaire covering dietary intake in the first trimester. The occurrence of wheezing and eczema was yearly assessed by questionnaires. RESULTS: Median weekly fish consumption was 83 (95% range 0-316) grams per week. We observed no consistent associations of maternal total-, lean- or fatty-fish consumption during pregnancy with the risks of childhood wheezing. Maternal shellfish consumption of 1-13 g per week was associated with overall increased risks of childhood wheezing and eczema (OR 1.20 (1.04, 1.40) and OR 1.18 (1.01, 1.37), respectively). Maternal fatty fish consumption of 35-69 g per week was associated with increased overall risks of childhood eczema (OR 1.17 (1.00, 1.38)), but maternal total- or lean-fish consumption was not. CONCLUSIONS: During pregnancy, shellfish consumption was associated with increased risks of wheezing and eczema, while fatty fish consumption was associated with a higher risk of eczema only. Maternal total fish or lean fish consumption were not associated with wheezing or eczema. Further studies are needed to replicate these findings and to explore underlying mechanisms. European Journal of Clinical Nutrition (2013) 67, 353-359; doi: 10.1038/ejcn.2013.36; published online 27 February 2013 Keywords: pregnancy; fish consumption; asthma symptoms; eczema; cohort study; atopy
language:
source:
identifier: ISSN: 0954-3007 ; E-ISSN: 1476-5640 ; DOI: 10.1038/ejcn.2013.36
fulltext: fulltext
issn:
  • 0954-3007
  • 09543007
  • 1476-5640
  • 14765640
url: Link


@attributes
ID1238770578
RANK0.07
NO1
SEARCH_ENGINEprimo_central_multiple_fe
SEARCH_ENGINE_TYPEPrimo Central Search Engine
LOCALfalse
PrimoNMBib
record
control
sourcerecordid10.1038/ejcn.2013.36
sourceidnature_a
recordidTN_nature_a10.1038/ejcn.2013.36
sourcesystemPC
pqid1348486802
galeid325092948
display
typearticle
titleMaternal fish consumption during pregnancy and risks of wheezing and eczema in childhood: The Generation R Study
creatorE T M Leermakers ; A M M Sonnenschein-Van Der Voort ; D H M Heppe ; J C De Jongste ; H A Moll ; O H Franco ; A Hofman ; V W V Jaddoe ; L Duijts
ispartofEuropean Journal of Clinical Nutrition, 2013, Vol.67(4), p.353
identifier
source
descriptionBACKGROUND/OBJECTIVES: Maternal fish consumption during pregnancy might influence the fetal immune system through anti-inflammatory effects of omega-3 fatty acids, and might affect the risks of childhood asthma and atopy. In Generation R, a prospective cohort study in the Netherlands, we examined the associations of first trimester fish consumption with childhood wheezing and eczema in the first 4 years of life. METHODS: In total, 2976 mothers completed a 293-item semiquantitative food frequency questionnaire covering dietary intake in the first trimester. The occurrence of wheezing and eczema was yearly assessed by questionnaires. RESULTS: Median weekly fish consumption was 83 (95% range 0-316) grams per week. We observed no consistent associations of maternal total-, lean- or fatty-fish consumption during pregnancy with the risks of childhood wheezing. Maternal shellfish consumption of 1-13 g per week was associated with overall increased risks of childhood wheezing and eczema (OR 1.20 (1.04, 1.40) and OR 1.18 (1.01, 1.37), respectively). Maternal fatty fish consumption of 35-69 g per week was associated with increased overall risks of childhood eczema (OR 1.17 (1.00, 1.38)), but maternal total- or lean-fish consumption was not. CONCLUSIONS: During pregnancy, shellfish consumption was associated with increased risks of wheezing and eczema, while fatty fish consumption was associated with a higher risk of eczema only. Maternal total fish or lean fish consumption were not associated with wheezing or eczema. Further studies are needed to replicate these findings and to explore underlying mechanisms. European Journal of Clinical Nutrition (2013) 67, 353-359; doi: 10.1038/ejcn.2013.36; published online 27 February 2013 Keywords: pregnancy; fish consumption; asthma symptoms; eczema; cohort study; atopy
subjectAsthma -- Risk Factors ; Asthma -- Diagnosis ; Eczema -- Diagnosis ; Eczema -- Risk Factors ; Fish (Food Product) -- Health Aspects ; Mothers -- Health Aspects ; Pregnant Women -- Health Aspects ; Wheezing -- Health Aspects;
version8
lds50peer_reviewed
links
openurl$$Topenurl_article
backlink$$Uhttp://dx.doi.org/10.1038/ejcn.2013.36$$EView_this_record_in_Nature
openurlfulltext$$Topenurlfull_article
search
creatorcontrib
0E T M Leermakers
1A M M Sonnenschein-Van Der Voort
2D H M Heppe
3J C De Jongste
4H A Moll
5O H Franco
6A Hofman
7V W V Jaddoe
8L Duijts
titleMaternal fish consumption during pregnancy and risks of wheezing and eczema in childhood: The Generation R Study
general
0Nature Publishing Group
110.1038/ejcn.2013.36
2nature.com (Nature Publishing Group)
sourceidnature_a
recordidnature_a10.1038/ejcn.2013.36
issn
00954-3007
109543007
21476-5640
314765640
rsrctypearticle
creationdate2013
searchscopenature_a
scopenature_a
lsr30VSR-Enriched:[description, pages, galeid, pqid, eissn, subject]
sort
titleMaternal fish consumption during pregnancy and risks of wheezing and eczema in childhood: The Generation R Study
authorE T M Leermakers ; A M M Sonnenschein-Van Der Voort ; D H M Heppe ; J C De Jongste ; H A Moll ; O H Franco ; A Hofman ; V W V Jaddoe ; L Duijts
creationdate20130227
facets
frbrgroupid6469892047178559406
frbrtype5
creationdate2013
collectionnature.com (Nature Publishing Group)
prefilterarticles
rsrctypearticles
creatorcontrib
0E T M Leermakers
1A M M Sonnenschein-Van Der Voort
2D H M Heppe
3J C De Jongste
4H A Moll
5O H Franco
6A Hofman
7V W V Jaddoe
8L Duijts
jtitleEuropean Journal Of Clinical Nutrition
toplevelpeer_reviewed
delivery
delcategoryRemote Search Resource
fulltextfulltext
addata
au
0E T M Leermakers
1A M M Sonnenschein-Van Der Voort
2D H M Heppe
3J C De Jongste
4H A Moll
5O H Franco
6A Hofman
7V W V Jaddoe
8L Duijts
atitleMaternal fish consumption during pregnancy and risks of wheezing and eczema in childhood: The Generation R Study
jtitleEuropean Journal of Clinical Nutrition
risdate20130227
volume67
issue4
spage353
issn0954-3007
genrearticle
ristypeJOUR
pubNature Publishing Group
doi10.1038/ejcn.2013.36
pages353-359
eissn14765640
date2013-02-27