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Same-Day Single Dose of 2 Liter Polyethylene Glycol is Not Inferior to The Standard Bowel Preparation Regimen in Low-Risk Patients: A Randomized, Controlled Trial

OBJECTIVES:: METHODS:: RESULTS:: Among 2,532 patients eligible for the study, 940 (37.1%) were at low risk and 792 (31.3%) at high risk for inadequate BP. The low-risk patients were randomly allocated to the SSL (n=470) or standard group (n=470). The baseline characteristics of the two groups were s... Full description

Journal Title: American Journal of Gastroenterology 2018, Vol.113(4), pp.601-610
Main Author: Kang, Xiaoyu
Other Authors: Zhao, Lina , Zhu, Zhiyong , Leung, Felix , Wang, Limei , Wang, Xiangping , Luo, Hui , Zhang, Linhui , Dong, Tao , Li, Pingying , Chen, Zhangqin , Ren, Gui , Jia, Hui , Guo, Xiaoyang , Pan, Yanglin , Guo, Xuegang , Fan, Daiming
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ID: ISSN: 0002-9270 ; DOI: 10.1038/ajg.2018.25
Link: http://ovidsp.ovid.com/ovidweb.cgi?T=JS&NEWS=n&CSC=Y&PAGE=fulltext&D=ovft&AN=00000434-201804000-00022
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title: Same-Day Single Dose of 2 Liter Polyethylene Glycol is Not Inferior to The Standard Bowel Preparation Regimen in Low-Risk Patients: A Randomized, Controlled Trial
format: Article
creator:
  • Kang, Xiaoyu
  • Zhao, Lina
  • Zhu, Zhiyong
  • Leung, Felix
  • Wang, Limei
  • Wang, Xiangping
  • Luo, Hui
  • Zhang, Linhui
  • Dong, Tao
  • Li, Pingying
  • Chen, Zhangqin
  • Ren, Gui
  • Jia, Hui
  • Guo, Xiaoyang
  • Pan, Yanglin
  • Guo, Xuegang
  • Fan, Daiming
subjects:
  • Colonoscopy
  • Cathartics -- Administration & Dosage
  • Polyethylene Glycols -- Administration & Dosage
ispartof: American Journal of Gastroenterology, 2018, Vol.113(4), pp.601-610
description: OBJECTIVES:: METHODS:: RESULTS:: Among 2,532 patients eligible for the study, 940 (37.1%) were at low risk and 792 (31.3%) at high risk for inadequate BP. The low-risk patients were randomly allocated to the SSL (n=470) or standard group (n=470). The baseline characteristics of the two groups were similar. Intention-to-treat analysis showed that adequate BP was achieved in 88.1% in the SSL group and 87.0% in the standard group (relative risk (RR) 1.10, 95% confidence interval (CI): 0.75–1.63, P=0.621). The overall BBPS was 7.3±1.2 and 7.3±1.3, respectively (P=0.948). No significant differences were found between the two groups with regards to the right, transverse, and left-segmental colon BBPS (all p>0.05). However, in terms of adverse events, patients in the SSL group reported less nausea (19.6% vs. 29.9%), vomiting (5.3% vs. 11.4%), and abdominal discomfort (2.2% vs. 6.0%) compared with those in the standard group. More patients in the SSL group were willing to repeat BP (94.0% vs. 89.5%, P=0.015). CONCLUSIONS::
language:
source:
identifier: ISSN: 0002-9270 ; DOI: 10.1038/ajg.2018.25
fulltext: fulltext
issn:
  • 0002-9270
  • 00029270
url: Link


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titleSame-Day Single Dose of 2 Liter Polyethylene Glycol is Not Inferior to The Standard Bowel Preparation Regimen in Low-Risk Patients: A Randomized, Controlled Trial
creatorKang, Xiaoyu ; Zhao, Lina ; Zhu, Zhiyong ; Leung, Felix ; Wang, Limei ; Wang, Xiangping ; Luo, Hui ; Zhang, Linhui ; Dong, Tao ; Li, Pingying ; Chen, Zhangqin ; Ren, Gui ; Jia, Hui ; Guo, Xiaoyang ; Pan, Yanglin ; Guo, Xuegang ; Fan, Daiming
ispartofAmerican Journal of Gastroenterology, 2018, Vol.113(4), pp.601-610
identifierISSN: 0002-9270 ; DOI: 10.1038/ajg.2018.25
descriptionOBJECTIVES:: METHODS:: RESULTS:: Among 2,532 patients eligible for the study, 940 (37.1%) were at low risk and 792 (31.3%) at high risk for inadequate BP. The low-risk patients were randomly allocated to the SSL (n=470) or standard group (n=470). The baseline characteristics of the two groups were similar. Intention-to-treat analysis showed that adequate BP was achieved in 88.1% in the SSL group and 87.0% in the standard group (relative risk (RR) 1.10, 95% confidence interval (CI): 0.75–1.63, P=0.621). The overall BBPS was 7.3±1.2 and 7.3±1.3, respectively (P=0.948). No significant differences were found between the two groups with regards to the right, transverse, and left-segmental colon BBPS (all P>0.05). However, in terms of adverse events, patients in the SSL group reported less nausea (19.6% vs. 29.9%), vomiting (5.3% vs. 11.4%), and abdominal discomfort (2.2% vs. 6.0%) compared with those in the standard group. More patients in the SSL group were willing to repeat BP (94.0% vs. 89.5%, P=0.015). CONCLUSIONS::
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subjectColonoscopy ; Cathartics -- Administration & Dosage ; Polyethylene Glycols -- Administration & Dosage;
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titleSame-Day Single Dose of 2 Liter Polyethylene Glycol is Not Inferior to The Standard Bowel Preparation Regimen in Low-Risk Patients: A Randomized, Controlled Trial
descriptionOBJECTIVES:: METHODS:: RESULTS:: Among 2,532 patients eligible for the study, 940 (37.1%) were at low risk and 792 (31.3%) at high risk for inadequate BP. The low-risk patients were randomly allocated to the SSL (n=470) or standard group (n=470). The baseline characteristics of the two groups were similar. Intention-to-treat analysis showed that adequate BP was achieved in 88.1% in the SSL group and 87.0% in the standard group (relative risk (RR) 1.10, 95% confidence interval (CI): 0.75–1.63, P=0.621). The overall BBPS was 7.3±1.2 and 7.3±1.3, respectively (P=0.948). No significant differences were found between the two groups with regards to the right, transverse, and left-segmental colon BBPS (all P>0.05). However, in terms of adverse events, patients in the SSL group reported less nausea (19.6% vs. 29.9%), vomiting (5.3% vs. 11.4%), and abdominal discomfort (2.2% vs. 6.0%) compared with those in the standard group. More patients in the SSL group were willing to repeat BP (94.0% vs. 89.5%, P=0.015). CONCLUSIONS::
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abstractOBJECTIVES:: METHODS:: RESULTS:: Among 2,532 patients eligible for the study, 940 (37.1%) were at low risk and 792 (31.3%) at high risk for inadequate BP. The low-risk patients were randomly allocated to the SSL (n=470) or standard group (n=470). The baseline characteristics of the two groups were similar. Intention-to-treat analysis showed that adequate BP was achieved in 88.1% in the SSL group and 87.0% in the standard group (relative risk (RR) 1.10, 95% confidence interval (CI): 0.75–1.63, P=0.621). The overall BBPS was 7.3±1.2 and 7.3±1.3, respectively (P=0.948). No significant differences were found between the two groups with regards to the right, transverse, and left-segmental colon BBPS (all P>0.05). However, in terms of adverse events, patients in the SSL group reported less nausea (19.6% vs. 29.9%), vomiting (5.3% vs. 11.4%), and abdominal discomfort (2.2% vs. 6.0%) compared with those in the standard group. More patients in the SSL group were willing to repeat BP (94.0% vs. 89.5%, P=0.015). CONCLUSIONS::
pub© The American College of Gastroenterology 2018. All Rights Reserved.
doi10.1038/ajg.2018.25
eissn15720241
date2018-04