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Frequency, Type, and Volume of Leisure-Time Physical Activity and Risk of Coronary Heart Disease in Young Women

BACKGROUND:: The inverse association between physical activity and coronary heart disease (CHD) risk has primarily been shown in studies of middle-aged and older adults. Evidence for the benefits of frequency, type, and volume of leisure-time physical activity in young women is limited. METHODS:: We... Full description

Journal Title: Circulation 2016, Vol.134(4), pp.290-299
Main Author: Chomistek, K., Andrea
Other Authors: Henschel, Heather, Beate , Eliassen, J., A. , Mukamal, B., Kenneth , Rimm, B., Eric
Format: Electronic Article Electronic Article
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ID: ISSN: 0009-7322 ; DOI: 10.1161/CIRCULATIONAHA.116.021516
Link: http://ovidsp.ovid.com/ovidweb.cgi?T=JS&NEWS=n&CSC=Y&PAGE=fulltext&D=ovft&AN=00003017-201607260-00005
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title: Frequency, Type, and Volume of Leisure-Time Physical Activity and Risk of Coronary Heart Disease in Young Women
format: Article
creator:
  • Chomistek, K., Andrea
  • Henschel, Heather, Beate
  • Eliassen, J., A.
  • Mukamal, B., Kenneth
  • Rimm, B., Eric
subjects:
  • Medicine
  • Anatomy & Physiology
ispartof: Circulation, 2016, Vol.134(4), pp.290-299
description: BACKGROUND:: The inverse association between physical activity and coronary heart disease (CHD) risk has primarily been shown in studies of middle-aged and older adults. Evidence for the benefits of frequency, type, and volume of leisure-time physical activity in young women is limited. METHODS:: We conducted a prospective analysis among 97 230 women aged 27 to 44 years at baseline in 1991. Leisure-time physical activity was assessed biennially by questionnaire. Cox proportional hazards models were used to examine the associations between physical activity frequency, type, and volume, and CHD risk. RESULTS:: During 20 years of follow-up, we documented 544 incident CHD cases. In multivariable-adjusted models, the hazard ratio (95% confidence interval) of CHD comparing ≥30 with
language:
source:
identifier: ISSN: 0009-7322 ; DOI: 10.1161/CIRCULATIONAHA.116.021516
fulltext: fulltext
issn:
  • 0009-7322
  • 00097322
url: Link


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titleFrequency, Type, and Volume of Leisure-Time Physical Activity and Risk of Coronary Heart Disease in Young Women
creatorChomistek, K., Andrea ; Henschel, Heather, Beate ; Eliassen, J., A. ; Mukamal, B., Kenneth ; Rimm, B., Eric
ispartofCirculation, 2016, Vol.134(4), pp.290-299
identifierISSN: 0009-7322 ; DOI: 10.1161/CIRCULATIONAHA.116.021516
descriptionBACKGROUND:: The inverse association between physical activity and coronary heart disease (CHD) risk has primarily been shown in studies of middle-aged and older adults. Evidence for the benefits of frequency, type, and volume of leisure-time physical activity in young women is limited. METHODS:: We conducted a prospective analysis among 97 230 women aged 27 to 44 years at baseline in 1991. Leisure-time physical activity was assessed biennially by questionnaire. Cox proportional hazards models were used to examine the associations between physical activity frequency, type, and volume, and CHD risk. RESULTS:: During 20 years of follow-up, we documented 544 incident CHD cases. In multivariable-adjusted models, the hazard ratio (95% confidence interval) of CHD comparing ≥30 with <1 metabolic equivalent of task-hours/wk of physical activity was 0.75 (0.57–0.99) (P, trend=0.01). Brisk walking alone was also associated with significantly lower CHD risk. Physical activity frequency was not associated with CHD risk when models also included overall activity volume. Finally, the association was not modified by body mass index (kg/m) (P, interaction=0.70). Active women (≥30 metabolic equivalent of task-hours/wk) with body mass index<25 kg/m had 0.52 (95% confidence interval, 0.35–0.78) times the rate of CHD in comparison with women who were obese (body mass index≥30 kg/m) and inactive (physical activity <1 metabolic equivalent of task-hours/wk). CONCLUSIONS:: These prospective data suggest that total volume of leisure-time physical activity is associated with lower risk of incident CHD among young women. In addition, this association was not modified by weight, emphasizing that it is important for normal weight, overweight, and obese women to be physically active.
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titleFrequency, Type, and Volume of Leisure-Time Physical Activity and Risk of Coronary Heart Disease in Young Women
descriptionBACKGROUND:: The inverse association between physical activity and coronary heart disease (CHD) risk has primarily been shown in studies of middle-aged and older adults. Evidence for the benefits of frequency, type, and volume of leisure-time physical activity in young women is limited. METHODS:: We conducted a prospective analysis among 97 230 women aged 27 to 44 years at baseline in 1991. Leisure-time physical activity was assessed biennially by questionnaire. Cox proportional hazards models were used to examine the associations between physical activity frequency, type, and volume, and CHD risk. RESULTS:: During 20 years of follow-up, we documented 544 incident CHD cases. In multivariable-adjusted models, the hazard ratio (95% confidence interval) of CHD comparing ≥30 with <1 metabolic equivalent of task-hours/wk of physical activity was 0.75 (0.57–0.99) (P, trend=0.01). Brisk walking alone was also associated with significantly lower CHD risk. Physical activity frequency was not associated with CHD risk when models also included overall activity volume. Finally, the association was not modified by body mass index (kg/m) (P, interaction=0.70). Active women (≥30 metabolic equivalent of task-hours/wk) with body mass index<25 kg/m had 0.52 (95% confidence interval, 0.35–0.78) times the rate of CHD in comparison with women who were obese (body mass index≥30 kg/m) and inactive (physical activity <1 metabolic equivalent of task-hours/wk). CONCLUSIONS:: These prospective data suggest that total volume of leisure-time physical activity is associated with lower risk of incident CHD among young women. In addition, this association was not modified by weight, emphasizing that it is important for normal weight, overweight, and obese women to be physically active.
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1© 2016 by the American College of Cardiology Foundation and the American Heart Association, Inc.
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abstractBACKGROUND:: The inverse association between physical activity and coronary heart disease (CHD) risk has primarily been shown in studies of middle-aged and older adults. Evidence for the benefits of frequency, type, and volume of leisure-time physical activity in young women is limited. METHODS:: We conducted a prospective analysis among 97 230 women aged 27 to 44 years at baseline in 1991. Leisure-time physical activity was assessed biennially by questionnaire. Cox proportional hazards models were used to examine the associations between physical activity frequency, type, and volume, and CHD risk. RESULTS:: During 20 years of follow-up, we documented 544 incident CHD cases. In multivariable-adjusted models, the hazard ratio (95% confidence interval) of CHD comparing ≥30 with <1 metabolic equivalent of task-hours/wk of physical activity was 0.75 (0.57–0.99) (P, trend=0.01). Brisk walking alone was also associated with significantly lower CHD risk. Physical activity frequency was not associated with CHD risk when models also included overall activity volume. Finally, the association was not modified by body mass index (kg/m) (P, interaction=0.70). Active women (≥30 metabolic equivalent of task-hours/wk) with body mass index<25 kg/m had 0.52 (95% confidence interval, 0.35–0.78) times the rate of CHD in comparison with women who were obese (body mass index≥30 kg/m) and inactive (physical activity <1 metabolic equivalent of task-hours/wk). CONCLUSIONS:: These prospective data suggest that total volume of leisure-time physical activity is associated with lower risk of incident CHD among young women. In addition, this association was not modified by weight, emphasizing that it is important for normal weight, overweight, and obese women to be physically active.
pub© 2016 by the American College of Cardiology Foundation and the American Heart Association, Inc.
doi10.1161/CIRCULATIONAHA.116.021516
eissn15244539
date2016-07-26