schliessen

Filtern

 

Bibliotheken

Epstein-Barr Virus Infection and Sporadic Breast Cancer Risk: A Meta-Analysis (Epstein-Barr Virus and Sporadic Breast Cancer Risk)

A large number of epidemiological studies have evaluated the association between Epstein-Barr virus infection and breast carcinoma risk but results have been inconsistent. ; Research using the polymerase chain reaction technique for detecting the Epstein-Barr virus was selected; 24 studies and 1535... Full description

Journal Title: PLoS ONE 2012, Vol.7(2), p.e31656
Main Author: Huo, Qiang
Other Authors: Zhang, Ning , Yang, Qifeng
Format: Electronic Article Electronic Article
Language: English
Subjects:
ID: E-ISSN: 1932-6203 ; DOI: 10.1371/journal.pone.0031656
Zum Text:
SendSend as email Add to Book BagAdd to Book Bag
Staff View
recordid: plos10.1371/journal.pone.0031656
title: Epstein-Barr Virus Infection and Sporadic Breast Cancer Risk: A Meta-Analysis (Epstein-Barr Virus and Sporadic Breast Cancer Risk)
format: Article
creator:
  • Huo, Qiang
  • Zhang, Ning
  • Yang, Qifeng
subjects:
  • Research Article
  • Medicine
  • Public Health And Epidemiology
  • Infectious Diseases
  • Oncology
ispartof: PLoS ONE, 2012, Vol.7(2), p.e31656
description: A large number of epidemiological studies have evaluated the association between Epstein-Barr virus infection and breast carcinoma risk but results have been inconsistent. ; Research using the polymerase chain reaction technique for detecting the Epstein-Barr virus was selected; 24 studies and 1535 cases were reviewed. Information on the study populations, sample types, publication calendar period and histological types of breast carcinoma were collected. An unconditional logistic regression model was used to analyze potential parameters related to the Epstein-Barr virus prevalence. A Kappa test was used to evaluate the consistency in detecting different Epstein-Barr virus DNA regions. Nine studies that included control groups and 1045 breast cancer cases were adopted in this meta-analysis. ; We found that 29.32% of the patients with breast carcinoma were infected with the Epstein-Barr virus. The prevalence of Epstein-Barr was highest in Asia (35.25%) and lowest in the USA (18.27%). Statistical analysis revealed a trend that showed lobular breast carcinoma might have the strongest association with Epstein-Barr virus infection. This meta-analysis showed a significant increase in breast malignancy risk in patients testing positive for the Epstein-Barr virus (OR = 6.29, 95% CI = 2.13–18.59). This result suggests that an Epstein-Barr virus infection is statistically associated with increased breast carcinoma risk.
language: eng
source:
identifier: E-ISSN: 1932-6203 ; DOI: 10.1371/journal.pone.0031656
fulltext: fulltext
issn:
  • 1932-6203
  • 19326203
url: Link


@attributes
ID329633886
RANK0.07
NO1
SEARCH_ENGINEprimo_central_multiple_fe
SEARCH_ENGINE_TYPEPrimo Central Search Engine
LOCALfalse
PrimoNMBib
record
control
sourcerecordid10.1371/journal.pone.0031656
sourceidplos
recordidTN_plos10.1371/journal.pone.0031656
sourcesystemOther
pqid1323855735
galeid477055594
display
typearticle
titleEpstein-Barr Virus Infection and Sporadic Breast Cancer Risk: A Meta-Analysis (Epstein-Barr Virus and Sporadic Breast Cancer Risk)
creatorHuo, Qiang ; Zhang, Ning ; Yang, Qifeng
contributorAziz, Syed A. (Editor)
ispartofPLoS ONE, 2012, Vol.7(2), p.e31656
identifierE-ISSN: 1932-6203 ; DOI: 10.1371/journal.pone.0031656
subjectResearch Article ; Medicine ; Public Health And Epidemiology ; Infectious Diseases ; Oncology
descriptionA large number of epidemiological studies have evaluated the association between Epstein-Barr virus infection and breast carcinoma risk but results have been inconsistent. ; Research using the polymerase chain reaction technique for detecting the Epstein-Barr virus was selected; 24 studies and 1535 cases were reviewed. Information on the study populations, sample types, publication calendar period and histological types of breast carcinoma were collected. An unconditional logistic regression model was used to analyze potential parameters related to the Epstein-Barr virus prevalence. A Kappa test was used to evaluate the consistency in detecting different Epstein-Barr virus DNA regions. Nine studies that included control groups and 1045 breast cancer cases were adopted in this meta-analysis. ; We found that 29.32% of the patients with breast carcinoma were infected with the Epstein-Barr virus. The prevalence of Epstein-Barr was highest in Asia (35.25%) and lowest in the USA (18.27%). Statistical analysis revealed a trend that showed lobular breast carcinoma might have the strongest association with Epstein-Barr virus infection. This meta-analysis showed a significant increase in breast malignancy risk in patients testing positive for the Epstein-Barr virus (OR = 6.29, 95% CI = 2.13–18.59). This result suggests that an Epstein-Barr virus infection is statistically associated with increased breast carcinoma risk.
languageeng
source
version9
lds50peer_reviewed
links
openurl$$Topenurl_article
openurlfulltext$$Topenurlfull_article
search
creatorcontrib
0Huo, Qiang
1Zhang, Ning
2Yang, Qifeng
3Aziz, Syed A. (Editor)
titleEpstein-Barr Virus Infection and Sporadic Breast Cancer Risk: A Meta-Analysis (Epstein-Barr Virus and Sporadic Breast Cancer Risk)
descriptionA large number of epidemiological studies have evaluated the association between Epstein-Barr virus infection and breast carcinoma risk but results have been inconsistent. ; Research using the polymerase chain reaction technique for detecting the Epstein-Barr virus was selected; 24 studies and 1535 cases were reviewed. Information on the study populations, sample types, publication calendar period and histological types of breast carcinoma were collected. An unconditional logistic regression model was used to analyze potential parameters related to the Epstein-Barr virus prevalence. A Kappa test was used to evaluate the consistency in detecting different Epstein-Barr virus DNA regions. Nine studies that included control groups and 1045 breast cancer cases were adopted in this meta-analysis. ; We found that 29.32% of the patients with breast carcinoma were infected with the Epstein-Barr virus. The prevalence of Epstein-Barr was highest in Asia (35.25%) and lowest in the USA (18.27%). Statistical analysis revealed a trend that showed lobular breast carcinoma might have the strongest association with Epstein-Barr virus infection. This meta-analysis showed a significant increase in breast malignancy risk in patients testing positive for the Epstein-Barr virus (OR = 6.29, 95% CI = 2.13–18.59). This result suggests that an Epstein-Barr virus infection is statistically associated with increased breast carcinoma risk.
subject
0Research Article
1Medicine
2Public Health And Epidemiology
3Infectious Diseases
4Oncology
general
010.1371/journal.pone.0031656
1English
sourceidplos
recordidplos10.1371/journal.pone.0031656
issn
01932-6203
119326203
rsrctypearticle
creationdate2012
recordtypearticle
addtitle
0PLoS ONE
1Epstein-Barr Virus and Sporadic Breast Cancer Risk
searchscopeplos
scopeplos
lsr30VSR-Enriched:[pqid, galeid]
sort
titleEpstein-Barr Virus Infection and Sporadic Breast Cancer Risk: A Meta-Analysis (Epstein-Barr Virus and Sporadic Breast Cancer Risk)
authorHuo, Qiang ; Zhang, Ning ; Yang, Qifeng
creationdate20120221
facets
frbrgroupid5510117417448868936
frbrtype5
languageeng
creationdate2012
topic
0Research Article
1Medicine
2Public Health And Epidemiology
3Infectious Diseases
4Oncology
collectionPLoS
prefilterarticles
rsrctypearticles
creatorcontrib
0Huo, Qiang
1Zhang, Ning
2Yang, Qifeng
3Aziz, Syed A.
jtitlePLoS ONE
toplevelpeer_reviewed
frbr
t2
k12012
k219326203
k310.1371/journal.pone.0031656
k47
k52
k631656
k7plos one
k8epstein barr virus infection sporadic breast cancer risk meta analysis
k9epsteinbarrvirusinfelysis
k12epsteinbarrvirusinfection
k15qianghuo
k16huoqiang
delivery
delcategoryRemote Search Resource
fulltextfulltext
ranking
booster11
booster21
pcg_typepublisher
addata
aulast
0Huo
1Zhang
2Yang
3Aziz
aufirst
0Qiang
1Ning
2Qifeng
3Syed A.
au
0Huo, Qiang
1Zhang, Ning
2Yang, Qifeng
addauAziz, Syed A.
atitleEpstein-Barr Virus Infection and Sporadic Breast Cancer Risk: A Meta-Analysis (Epstein-Barr Virus and Sporadic Breast Cancer Risk)
jtitlePLoS ONE
risdate20120221
volume7
issue2
spagee31656
pagese31656
eissn1932-6203
genrearticle
ristypeJOUR
abstractA large number of epidemiological studies have evaluated the association between Epstein-Barr virus infection and breast carcinoma risk but results have been inconsistent. ; Research using the polymerase chain reaction technique for detecting the Epstein-Barr virus was selected; 24 studies and 1535 cases were reviewed. Information on the study populations, sample types, publication calendar period and histological types of breast carcinoma were collected. An unconditional logistic regression model was used to analyze potential parameters related to the Epstein-Barr virus prevalence. A Kappa test was used to evaluate the consistency in detecting different Epstein-Barr virus DNA regions. Nine studies that included control groups and 1045 breast cancer cases were adopted in this meta-analysis. ; We found that 29.32% of the patients with breast carcinoma were infected with the Epstein-Barr virus. The prevalence of Epstein-Barr was highest in Asia (35.25%) and lowest in the USA (18.27%). Statistical analysis revealed a trend that showed lobular breast carcinoma might have the strongest association with Epstein-Barr virus infection. This meta-analysis showed a significant increase in breast malignancy risk in patients testing positive for the Epstein-Barr virus (OR = 6.29, 95% CI = 2.13–18.59). This result suggests that an Epstein-Barr virus infection is statistically associated with increased breast carcinoma risk.
copSan Francisco, USA
pubPublic Library of Science
doi10.1371/journal.pone.0031656
oafree_for_read
date2012-02-21