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Warfarin and aspirin in patients with heart failure and sinus rhythm.

BACKGROUNDIt is unknown whether warfarin or aspirin therapy is superior for patients with heart failure who are in sinus rhythm. METHODSWe designed this trial to determine whether warfarin (with a target international normalized ratio of 2.0 to 3.5) or aspirin (at a dose of 325 mg per day) is a bett... Full description

Journal Title: The New England journal of medicine May 17, 2012, Vol.366(20), pp.1859-1869
Main Author: Homma, Shunichi
Other Authors: Thompson, John L P , Pullicino, Patrick M , Levin, Bruce , Freudenberger, Ronald S , Teerlink, John R , Ammon, Susan E , Graham, Susan , Sacco, Ralph L , Mann, Douglas L , Mohr, J P , Massie, Barry M , Labovitz, Arthur J , Anker, Stefan D , Lok, Dirk J , Ponikowski, Piotr , Estol, Conrado J , Lip, Gregory Y H , Di Tullio, Marco R , Sanford, Alexandra R , Mejia, Vilma , Gabriel, Andre P , Del Valle, Mirna L , Buchsbaum, Richard , Homma, Shunichi
Format: Electronic Article Electronic Article
Language: English
Subjects:
ID: E-ISSN: 1533-4406 ; DOI: 10.1056/NEJMoa1202299
Link: http://search.proquest.com/docview/1015097333/?pq-origsite=primo
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title: Warfarin and aspirin in patients with heart failure and sinus rhythm.
format: Article
creator:
  • Homma, Shunichi
  • Thompson, John L P
  • Pullicino, Patrick M
  • Levin, Bruce
  • Freudenberger, Ronald S
  • Teerlink, John R
  • Ammon, Susan E
  • Graham, Susan
  • Sacco, Ralph L
  • Mann, Douglas L
  • Mohr, J P
  • Massie, Barry M
  • Labovitz, Arthur J
  • Anker, Stefan D
  • Lok, Dirk J
  • Ponikowski, Piotr
  • Estol, Conrado J
  • Lip, Gregory Y H
  • Di Tullio, Marco R
  • Sanford, Alexandra R
  • Mejia, Vilma
  • Gabriel, Andre P
  • Del Valle, Mirna L
  • Buchsbaum, Richard
  • Homma, Shunichi
subjects:
  • Aged–Adverse Effects
  • Anticoagulants–Therapeutic Use
  • Aspirin–Adverse Effects
  • Brain Ischemia–Therapeutic Use
  • Cerebral Hemorrhage–Prevention & Control
  • Double-Blind Method–Chemically Induced
  • Female–Drug Therapy
  • Follow-Up Studies–Mortality
  • Heart Failure–Physiopathology
  • Hemorrhage–Chemically Induced
  • Humans–Epidemiology
  • Male–Adverse Effects
  • Middle Aged–Therapeutic Use
  • Platelet Aggregation Inhibitors–Epidemiology
  • Risk–Prevention & Control
  • Stroke–Adverse Effects
  • Stroke Volume–Therapeutic Use
  • Treatment Outcome–Therapeutic Use
  • Warfarin–Therapeutic Use
  • Abridged
  • Anticoagulants
  • Platelet Aggregation Inhibitors
  • Warfarin
  • Aspirin
ispartof: The New England journal of medicine, May 17, 2012, Vol.366(20), pp.1859-1869
description: BACKGROUNDIt is unknown whether warfarin or aspirin therapy is superior for patients with heart failure who are in sinus rhythm. METHODSWe designed this trial to determine whether warfarin (with a target international normalized ratio of 2.0 to 3.5) or aspirin (at a dose of 325 mg per day) is a better...
language: eng
source:
identifier: E-ISSN: 1533-4406 ; DOI: 10.1056/NEJMoa1202299
fulltext: fulltext
issn:
  • 15334406
  • 1533-4406
url: Link


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titleWarfarin and aspirin in patients with heart failure and sinus rhythm.
creatorHomma, Shunichi ; Thompson, John L P ; Pullicino, Patrick M ; Levin, Bruce ; Freudenberger, Ronald S ; Teerlink, John R ; Ammon, Susan E ; Graham, Susan ; Sacco, Ralph L ; Mann, Douglas L ; Mohr, J P ; Massie, Barry M ; Labovitz, Arthur J ; Anker, Stefan D ; Lok, Dirk J ; Ponikowski, Piotr ; Estol, Conrado J ; Lip, Gregory Y H ; Di Tullio, Marco R ; Sanford, Alexandra R ; Mejia, Vilma ; Gabriel, Andre P ; Del Valle, Mirna L ; Buchsbaum, Richard ; Homma, Shunichi
contributorHomma, S (correspondence author) ; Thompson, J L P (record owner) ; Pullicino, P ; Freudenberger, R ; Graham, S ; Teerlink, J ; Ammon, S ; Mann, D ; Mohr, J P ; Sacco, R L ; Massie, B ; Anker, S ; Labovitz, A ; Moy, C ; Moy, C ; Gilbert, P ; Gutmann, L ; Marler, J ; Homma, S ; Mejia, V ; Gabriel, A ; Borden, S ; Peña, E ; Harris, C ; Khadouri, R ; Gohs, D ; Brown, M ; Berry, G ; Disantis, D ; Scullin, M ; Smith, P ; Kohsaka, S ; Watson, W ; Guillory, L ; Thompson, J L P ; Levin, B ; Buchsbaum, R ; Del Valle, M ; Sanford, A ; Levy, G ; Tea, K ; Grier, J ; Swydan, L ; O'Hare, B ; Prodhan, R ; Arbing, R ; Flanagan, E ; Duverger, E ; Peljto, A ; Lo, W ; Tierney, A ; Henriquez, A ; Keen, J ; Del Zoppo, G J ; Albers, G W ; Eliasziw, M ; Hinchey, J A ; Johnston, K C ; Lowe, A M ; Piña, I L ; Swain, J A ; Teerlink, J R ; Ammon, S ; Slomiak, S ; Cape, L ; Barnett, H J M ; Bruno, A ; Easton, J D ; Levine, S ; Sahlas, D ; Bleyer, F ; Carson, P ; Ellis, A ; Miller, A ; Palmeri, S T ; Labovitz, A ; Di Tullio, M ; Bierig, M ; Liu, R ; Donato, C ; Hart, R ; Mckay, C ; Wilson, L ; Frey, E ; Hayward, K ; Stein-Beal, P ; Konczarek, L ; Diek, M ; Rohwedder, M ; Bohdanowicz-Zazula, M ; Peerenboom-Fey, C F ; Vissiennon, M ; Rex, G ; Varga, M ; Kovtun, O ; Orlyk, V ; Arenberger, P ; Jaros, J ; Ruiz, A ; Zimmermann, M ; Ellenberg, A ; Minagar, A ; Kelley, R ; Mcgee, J ; Jinkins, P ; Bezucha, S ; Graham, S ; Hart, V ; Bonora, M ; Sawyer, R ; Ammerman, K ; Ramappa, P ; Berchou, V ; Jones, E ; Olgren, E ; Hattler, B ; Anderson, C ; Watson, B ; Wolf, D ; Kosits, J ; Casazza, L ; Yip, D ; Meschia, J ; Mcphail, A ; Greenan, K ; Rothbart, R ; Love, J ; Schrader, T ; Garman, V ; Stoddard, M ; Remmel, K ; Longaker, R ; Gerula, C ; Klapholz, M ; Kirmani, J ; Mattessich, R ; Di Tullio, M ; Rodriguez, C ; Gabriel, A ; Graettinger, W ; Baker, A ; Valencia, A ; Kosolcharoen, P ; Williams, L ; Sorrell, V ; Coull, B ; Bruck, D ; Ofili, E ; Frankel, M ; Jackson, P ; Nanna, M ; Sparr, S ; Almeida, W ; Libman, R ; Stephens, B ; Demers, C ; Giles, T ; Roffidal, L ; Barratt, D ; Liston, M ; Lindsey, C ; Giron, L ; Felton, W ; Joseph, L ; Lee, M ; Bisognano, J ; Benesch, C ; Caufield, L ; Nishime, E ; Moussavian, M ; Polland, E ; Fischer, L ; Peterson, K ; Mcginnis, B ; Tilem, M ; Allam, G ; Beebe, J ; Chang, P ; Sen, S ; Schuler, C ; Arcement, L ; Charlet, M ; Falgout, E ; Malkowski, M ; Dugan, T ; Hobbs-Williams, J ; Warner, A ; Panizzon, K ; Johnson, J ; Dissin, J ; Karia, D ; Molakala, N ; Dandapani, B ; Vicari, R ; Anthony, E ; Katzan, I ; Hobbs, R ; Richmond, A ; Hughes, R ; Baker, W ; Applegate, M ; Drachman, B ; Khella, S ; Donovan, S ; Slim, A ; Pearce Moore, D ; Darrow, B ; Travis, A ; Mercando, A ; Pellegrino, R ; Jarmukli, N ; Ochalek, T ; Janosik, D ; Dizes, J ; Pettigrew, L C ; Taylor, D ; Hanna, J ; Bailey, S ; Berkowitz, R ; Mathus, S ; Virkud, V ; Shaw, S ; Freudenberger, R ; Nabhan, S ; Wirkowski, E
ispartofThe New England journal of medicine, May 17, 2012, Vol.366(20), pp.1859-1869
identifierE-ISSN: 1533-4406 ; DOI: 10.1056/NEJMoa1202299
subjectAged–Adverse Effects ; Anticoagulants–Therapeutic Use ; Aspirin–Adverse Effects ; Brain Ischemia–Therapeutic Use ; Cerebral Hemorrhage–Prevention & Control ; Double-Blind Method–Chemically Induced ; Female–Drug Therapy ; Follow-Up Studies–Mortality ; Heart Failure–Physiopathology ; Hemorrhage–Chemically Induced ; Humans–Epidemiology ; Male–Adverse Effects ; Middle Aged–Therapeutic Use ; Platelet Aggregation Inhibitors–Epidemiology ; Risk–Prevention & Control ; Stroke–Adverse Effects ; Stroke Volume–Therapeutic Use ; Treatment Outcome–Therapeutic Use ; Warfarin–Therapeutic Use ; Abridged ; Anticoagulants ; Platelet Aggregation Inhibitors ; Warfarin ; Aspirin
descriptionBACKGROUNDIt is unknown whether warfarin or aspirin therapy is superior for patients with heart failure who are in sinus rhythm. METHODSWe designed this trial to determine whether warfarin (with a target international normalized ratio of 2.0 to 3.5) or aspirin (at a dose of 325 mg per day) is a better...
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17Lip, Gregory Y H
18Di Tullio, Marco R
19Sanford, Alexandra R
20Mejia, Vilma
21Gabriel, Andre P
22Del Valle, Mirna L
23Buchsbaum, Richard
titleWarfarin and aspirin in patients with heart failure and sinus rhythm.
descriptionBACKGROUNDIt is unknown whether warfarin or aspirin therapy is superior for patients with heart failure who are in sinus rhythm. METHODSWe designed this trial to determine whether warfarin (with a target international normalized ratio of 2.0 to 3.5) or aspirin (at a dose of 325 mg per day) is a better...
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21Harris, C
22Khadouri, R
23Gohs, D
24Brown, M
25Berry, G
26Disantis, D
27Scullin, M
28Smith, P
29Kohsaka, S
30Watson, W
31Guillory, L
32Levin, B
33Buchsbaum, R
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titleWarfarin and aspirin in patients with heart failure and sinus rhythm.
authorHomma, Shunichi ; Thompson, John L P ; Pullicino, Patrick M ; Levin, Bruce ; Freudenberger, Ronald S ; Teerlink, John R ; Ammon, Susan E ; Graham, Susan ; Sacco, Ralph L ; Mann, Douglas L ; Mohr, J P ; Massie, Barry M ; Labovitz, Arthur J ; Anker, Stefan D ; Lok, Dirk J ; Ponikowski, Piotr ; Estol, Conrado...
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3Brain Ischemia–Therapeutic Use
4Cerebral Hemorrhage–Prevention & Control
5Double-Blind Method–Chemically Induced
6Female–Drug Therapy
7Follow-Up Studies–Mortality
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atitleWarfarin and aspirin in patients with heart failure and sinus rhythm.
jtitleThe New England journal of medicine
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volume366
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abstractBACKGROUNDIt is unknown whether warfarin or aspirin therapy is superior for patients with heart failure who are in sinus rhythm. METHODSWe designed this trial to determine whether warfarin (with a target international normalized ratio of 2.0 to 3.5) or aspirin (at a dose of 325 mg per day) is a better...
doi10.1056/NEJMoa1202299
urlhttp://search.proquest.com/docview/1015097333/
issn00284793
date2012-05-17