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The history and role of long duration stimulation in fMRI.

To link to full-text access for this article, visit this link: http://dx.doi.org/10.1016/j.neuroimage.2012.01.045 Byline: Gunnar Krueger, Cristina Granziera Keywords: fMRI; Long stimulation Abstract: During the past 20years, BOLD fMRI has developed towards a central and fundamental tool in neuroscie... Full description

Journal Title: NeuroImage Vol.62(2), pp.1051-1055
Main Author: Krueger, Gunnar
Other Authors: Granziera, Cristina
Format: Electronic Article Electronic Article
Language: English
Subjects:
Created: August 15, 2012
ID: E-ISSN: 1095-9572 ; DOI: 1095-9572 ; DOI: 10.1016/j.neuroimage.2012.01.045
Link: http://search.proquest.com/docview/1023295304/?pq-origsite=primo
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title: The history and role of long duration stimulation in fMRI.
format: Article
creator:
  • Krueger, Gunnar
  • Granziera, Cristina
subjects:
  • Animals–Blood Supply
  • Brain–Physiology
  • Brain Mapping–History
  • Cerebrovascular Circulation–Methods
  • History, 20th Century–Physiology
  • History, 21st Century–History
  • Humans–Methods
  • Magnetic Resonance Imaging–Blood
  • Oxygen–Blood
  • Oxygen
ispartof: NeuroImage, Vol.62(2), pp.1051-1055
description: To link to full-text access for this article, visit this link: http://dx.doi.org/10.1016/j.neuroimage.2012.01.045 Byline: Gunnar Krueger, Cristina Granziera Keywords: fMRI; Long stimulation Abstract: During the past 20years, BOLD fMRI has developed towards a central and fundamental tool in neuroscience. It has been shown that the BOLD response provides an indicator of neuronal activity in the brain. Consequently, for an accurate interpretation of findings in BOLD MRI experiments and to draw meaningful conclusions about the temporal evolution of neural events, a deep understanding of the nature of the BOLD contrast has become of essential importance. Since the dynamics of the major direct determinants of the BOLD signal (CBF, CBV and CMRO.sub.2) range between seconds and minutes, long duration stimulation was an early key strategy needed to study and understand the BOLD characteristics. This paper summarizes and discusses the thoughts and rationales of the long duration stimulation studies. Article History: Accepted 5 January 2012
language: eng
source:
identifier: E-ISSN: 1095-9572 ; DOI: 1095-9572 ; DOI: 10.1016/j.neuroimage.2012.01.045
fulltext: fulltext
issn:
  • 10959572
  • 1095-9572
url: Link


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titleThe history and role of long duration stimulation in fMRI.
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