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After treat-to-target: can a targeted ultrasound initiative improve RA outcomes?

For patients with rheumatoid arthritis (RA), remission can be achieved with tight control of inflammation and early use of disease modifying agents. The importance of remission as an outcome has been recently highlighted by European League Against Rheumatism recommendations. However, remission when... Full description

Journal Title: Postgraduate medical journal August 2012, Vol.88(1042), pp.482-486
Main Author: Wakefield, Richard J
Other Authors: D'Agostino, Maria Antonietta , Naredo, Esperanza , Buch, Maya H , Iagnocco, Annamaria , Terslev, Lene , Ostergaard, Mikkel , Backhaus, Marina , Grassi, Walter , Dougados, Maxime , Burmester, Gerd R , Saleem, Benazir , de Miguel, Eugenio , Estrach, Cristina , Ikeda, Kei , Gutierrez, Marwin , Thompson, Robert , Balint, Peter , Emery, Paul
Format: Electronic Article Electronic Article
Language: English
Subjects:
ID: E-ISSN: 1469-0756 ; DOI: 10.1136/postgradmedj-2011-201048rep
Link: http://search.proquest.com/docview/1027681013/?pq-origsite=primo
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title: After treat-to-target: can a targeted ultrasound initiative improve RA outcomes?
format: Article
creator:
  • Wakefield, Richard J
  • D'Agostino, Maria Antonietta
  • Naredo, Esperanza
  • Buch, Maya H
  • Iagnocco, Annamaria
  • Terslev, Lene
  • Ostergaard, Mikkel
  • Backhaus, Marina
  • Grassi, Walter
  • Dougados, Maxime
  • Burmester, Gerd R
  • Saleem, Benazir
  • de Miguel, Eugenio
  • Estrach, Cristina
  • Ikeda, Kei
  • Gutierrez, Marwin
  • Thompson, Robert
  • Balint, Peter
  • Emery, Paul
subjects:
  • Antirheumatic Agents–Therapeutic Use
  • Arthritis, Rheumatoid–Diagnostic Imaging
  • Humans–Therapy
  • Remission Induction–Diagnostic Imaging
  • Severity of Illness Index–Therapy
  • Synovitis–Therapy
  • Time Factors–Therapy
  • Treatment Outcome–Therapy
  • Ultrasonography–Therapy
  • Antirheumatic Agents
ispartof: Postgraduate medical journal, August 2012, Vol.88(1042), pp.482-486
description: For patients with rheumatoid arthritis (RA), remission can be achieved with tight control of inflammation and early use of disease modifying agents. The importance of remission as an outcome has been recently highlighted by European League Against Rheumatism recommendations. However, remission when defined by clinical remission criteria (disease activity score, simplified disease activity index, etc) does not always equate to the complete absence of inflammation as measured by new sensitive imaging techniques such as ultrasound (US) . There is evidence that imaging synovitis is frequently found in these patients and associated with adverse clinical and functional outcomes. This article reviews the data regarding remission, ultrasound imaging and outcomes in patients with RA to provide the background to a consensus statement from an international collaboration of ultrasonographers and rheumatologists who have recently formed a research network - the Targeted Ultrasound Initiative (TUI) group....
language: eng
source:
identifier: E-ISSN: 1469-0756 ; DOI: 10.1136/postgradmedj-2011-201048rep
fulltext: fulltext
issn:
  • 14690756
  • 1469-0756
url: Link


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titleAfter treat-to-target: can a targeted ultrasound initiative improve RA outcomes?
creatorWakefield, Richard J ; D'Agostino, Maria Antonietta ; Naredo, Esperanza ; Buch, Maya H ; Iagnocco, Annamaria ; Terslev, Lene ; Ostergaard, Mikkel ; Backhaus, Marina ; Grassi, Walter ; Dougados, Maxime ; Burmester, Gerd R ; Saleem, Benazir ; de Miguel, Eugenio ; Estrach, Cristina ; Ikeda, Kei ; Gutierrez, Marwin ; Thompson, Robert ; Balint, Peter ; Emery, Paul
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identifierE-ISSN: 1469-0756 ; DOI: 10.1136/postgradmedj-2011-201048rep
subjectAntirheumatic Agents–Therapeutic Use ; Arthritis, Rheumatoid–Diagnostic Imaging ; Humans–Therapy ; Remission Induction–Diagnostic Imaging ; Severity of Illness Index–Therapy ; Synovitis–Therapy ; Time Factors–Therapy ; Treatment Outcome–Therapy ; Ultrasonography–Therapy ; Antirheumatic Agents
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descriptionFor patients with rheumatoid arthritis (RA), remission can be achieved with tight control of inflammation and early use of disease modifying agents. The importance of remission as an outcome has been recently highlighted by European League Against Rheumatism recommendations. However, remission when defined by clinical remission criteria (disease activity score, simplified disease activity index, etc) does not always equate to the complete absence of inflammation as measured by new sensitive imaging techniques such as ultrasound (US) . There is evidence that imaging synovitis is frequently found in these patients and associated with adverse clinical and functional outcomes. This article reviews the data regarding remission, ultrasound imaging and outcomes in patients with RA to provide the background to a consensus statement from an international collaboration of ultrasonographers and rheumatologists who have recently formed a research network - the Targeted Ultrasound Initiative (TUI) group....
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