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Is obstructive sleep apnea associated with cardiovascular and all-cause mortality?

BACKGROUNDStudies have reported inconsistent findings regarding the association between obstructive sleep apnea (OSA) and future risks of cardiovascular and all-cause mortality. We conducted a meta-analysis to investigate whether OSA is an independent predictor for future cardiovascular and all-caus... Full description

Journal Title: PloS one 2013, Vol.8(7), p.e69432
Main Author: Ge, Xiahui
Other Authors: Han, Fengfeng , Huang, Yanxi , Zhang, Yue , Yang, Tianyun , Bai, Chong , Guo, Xuejun
Format: Electronic Article Electronic Article
Language: English
Subjects:
ID: E-ISSN: 1932-6203 ; DOI: 10.1371/journal.pone.0069432
Link: http://search.proquest.com/docview/1420161697/?pq-origsite=primo
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recordid: proquest1420161697
title: Is obstructive sleep apnea associated with cardiovascular and all-cause mortality?
format: Article
creator:
  • Ge, Xiahui
  • Han, Fengfeng
  • Huang, Yanxi
  • Zhang, Yue
  • Yang, Tianyun
  • Bai, Chong
  • Guo, Xuejun
subjects:
  • Adult–Etiology
  • Cardiovascular Diseases–Mortality
  • Databases, Bibliographic–Physiopathology
  • Female–Therapy
  • Humans–Complications
  • Male–Mortality
  • Middle Aged–Physiopathology
  • Mortality–Therapy
  • Proportional Hazards Models–Therapy
  • Prospective Studies–Therapy
  • Risk Factors–Therapy
  • Sleep Apnea, Obstructive–Therapy
  • Survival Analysis–Therapy
ispartof: PloS one, 2013, Vol.8(7), p.e69432
description: BACKGROUNDStudies have reported inconsistent findings regarding the association between obstructive sleep apnea (OSA) and future risks of cardiovascular and all-cause mortality. We conducted a meta-analysis to investigate whether OSA is an independent predictor for future cardiovascular and all-cause mortality using prospective observational studies. METHODSElectronic literature databases (Medline and Embase) were searched for prospective observational studies published prior to December 2012. Only observational studies that assessed baseline OSA and future risk of cardiovascular and all-cause mortality were selected. Pooled hazard risk (HR) and corresponding 95% confidence intervals (CI) were calculated for categorical risk estimates. Subgroup analyses were based on the severity of OSA. RESULTSSix studies with 11932 patients were identified and analyzed, with 239 reporting cardiovascular mortality, and 1397 all-cause mortality. Pooled HR of all-cause mortality was 1.19 (95% CI, 1.00 to...
language: eng
source:
identifier: E-ISSN: 1932-6203 ; DOI: 10.1371/journal.pone.0069432
fulltext: fulltext
issn:
  • 19326203
  • 1932-6203
url: Link


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titleIs obstructive sleep apnea associated with cardiovascular and all-cause mortality?
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identifierE-ISSN: 1932-6203 ; DOI: 10.1371/journal.pone.0069432
subjectAdult–Etiology ; Cardiovascular Diseases–Mortality ; Databases, Bibliographic–Physiopathology ; Female–Therapy ; Humans–Complications ; Male–Mortality ; Middle Aged–Physiopathology ; Mortality–Therapy ; Proportional Hazards Models–Therapy ; Prospective Studies–Therapy ; Risk Factors–Therapy ; Sleep Apnea, Obstructive–Therapy ; Survival Analysis–Therapy
descriptionBACKGROUNDStudies have reported inconsistent findings regarding the association between obstructive sleep apnea (OSA) and future risks of cardiovascular and all-cause mortality. We conducted a meta-analysis to investigate whether OSA is an independent predictor for future cardiovascular and all-cause mortality using prospective observational studies. METHODSElectronic literature databases (Medline and Embase) were searched for prospective observational studies published prior to December 2012. Only observational studies that assessed baseline OSA and future risk of cardiovascular and all-cause mortality were selected. Pooled hazard risk (HR) and corresponding 95% confidence intervals (CI) were calculated for categorical risk estimates. Subgroup analyses were based on the severity of OSA. RESULTSSix studies with 11932 patients were identified and analyzed, with 239 reporting cardiovascular mortality, and 1397 all-cause mortality. Pooled HR of all-cause mortality was 1.19 (95% CI, 1.00 to...
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abstractBACKGROUNDStudies have reported inconsistent findings regarding the association between obstructive sleep apnea (OSA) and future risks of cardiovascular and all-cause mortality. We conducted a meta-analysis to investigate whether OSA is an independent predictor for future cardiovascular and all-cause mortality using prospective observational studies. METHODSElectronic literature databases (Medline and Embase) were searched for prospective observational studies published prior to December 2012. Only observational studies that assessed baseline OSA and future risk of cardiovascular and all-cause mortality were selected. Pooled hazard risk (HR) and corresponding 95% confidence intervals (CI) were calculated for categorical risk estimates. Subgroup analyses were based on the severity of OSA. RESULTSSix studies with 11932 patients were identified and analyzed, with 239 reporting cardiovascular mortality, and 1397 all-cause mortality. Pooled HR of all-cause mortality was 1.19 (95% CI, 1.00 to...
doi10.1371/journal.pone.0069432
urlhttp://search.proquest.com/docview/1420161697/
date2013-01-01