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The Effect of L-Ascorbic Acid-2-Phosphate Magnesium on Chicks Injected a Radical Initiator

  Effect of L-ascorbic acid phosphate magnesium (APM) on chicks injected radical initiator, 2, 2'-azobis(2-amidinopropane) dihydrochloride (AAPH), was examined. Chicks were fed APM as ascorbate resource for 7 days. Birds were administrated AAPH by intraperitoneal injection after APM feeding. The cha... Full description

Journal Title: The Journal of Poultry Science 2002, Vol.39(3), p.179
Main Author: Sasaki, Keisuke
Other Authors: Sano, Mitsuaki , Satoh, Jun-Ichi , Ohishi, Yukou , Itoh, Shinobu , Nakaya, Tetsuro , Aoyagi, Yosuke
Format: Electronic Article Electronic Article
Language: English
Subjects:
ID: ISSN: 13467395 ; E-ISSN: 13490486
Link: http://search.proquest.com/docview/1439290815/?pq-origsite=primo
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recordid: proquest1439290815
title: The Effect of L-Ascorbic Acid-2-Phosphate Magnesium on Chicks Injected a Radical Initiator
format: Article
creator:
  • Sasaki, Keisuke
  • Sano, Mitsuaki
  • Satoh, Jun-Ichi
  • Ohishi, Yukou
  • Itoh, Shinobu
  • Nakaya, Tetsuro
  • Aoyagi, Yosuke
subjects:
  • Chick
  • L-Ascorbic Acid-2-Phosphate Magnesium
  • Radical Initiator
  • Oxidative Stress
ispartof: The Journal of Poultry Science, 2002, Vol.39(3), p.179
description:   Effect of L-ascorbic acid phosphate magnesium (APM) on chicks injected radical initiator, 2, 2'-azobis(2-amidinopropane) dihydrochloride (AAPH), was examined. Chicks were fed APM as ascorbate resource for 7 days. Birds were administrated AAPH by intraperitoneal injection after APM feeding. The changes of ascorbate and thiobarbituric acid reactive substances (TBARS) in plasma and liver were determined before, and 3 and 6 hours after AAPH injection. Both plasma and liver ascorbate increased by APM feeding. After AAPH injection, liver ascorbate decreased, but plasma ascorbate increased in both control and APM-fed birds. AAPH administration raised liver TBARS, but decreased plasma TBARS. Both plasma and liver TBARS were lower in APM group than control group before and after AAPH administration. Peroxyl radical trapping activity in plasma was elevated by APM feeding as compared to control group. APM was utilized as ascorbate, and was effective for prevention of oxidative stresses derived from AAPH by increasing plasma and liver ascorbate and plasma radical trapping activity.
language: eng
source:
identifier: ISSN: 13467395 ; E-ISSN: 13490486
fulltext: fulltext
issn:
  • 13467395
  • 1346-7395
  • 13490486
  • 1349-0486
url: Link


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titleThe Effect of L-Ascorbic Acid-2-Phosphate Magnesium on Chicks Injected a Radical Initiator
creatorSasaki, Keisuke ; Sano, Mitsuaki ; Satoh, Jun-Ichi ; Ohishi, Yukou ; Itoh, Shinobu ; Nakaya, Tetsuro ; Aoyagi, Yosuke
ispartofThe Journal of Poultry Science, 2002, Vol.39(3), p.179
identifierISSN: 13467395 ; E-ISSN: 13490486
description  Effect of L-ascorbic acid phosphate magnesium (APM) on chicks injected radical initiator, 2, 2'-azobis(2-amidinopropane) dihydrochloride (AAPH), was examined. Chicks were fed APM as ascorbate resource for 7 days. Birds were administrated AAPH by intraperitoneal injection after APM feeding. The changes of ascorbate and thiobarbituric acid reactive substances (TBARS) in plasma and liver were determined before, and 3 and 6 hours after AAPH injection. Both plasma and liver ascorbate increased by APM feeding. After AAPH injection, liver ascorbate decreased, but plasma ascorbate increased in both control and APM-fed birds. AAPH administration raised liver TBARS, but decreased plasma TBARS. Both plasma and liver TBARS were lower in APM group than control group before and after AAPH administration. Peroxyl radical trapping activity in plasma was elevated by APM feeding as compared to control group. APM was utilized as ascorbate, and was effective for prevention of oxidative stresses derived from AAPH by increasing plasma and liver ascorbate and plasma radical trapping activity.
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titleThe Effect of L-Ascorbic Acid-2-Phosphate Magnesium on Chicks Injected a Radical Initiator
description  Effect of L-ascorbic acid phosphate magnesium (APM) on chicks injected radical initiator, 2, 2'-azobis(2-amidinopropane) dihydrochloride (AAPH), was examined. Chicks were fed APM as ascorbate resource for 7 days. Birds were administrated AAPH by intraperitoneal injection after APM feeding. The changes of ascorbate and thiobarbituric acid reactive substances (TBARS) in plasma and liver were determined before, and 3 and 6 hours after AAPH injection. Both plasma and liver ascorbate increased by APM feeding. After AAPH injection, liver ascorbate decreased, but plasma ascorbate increased in both control and APM-fed birds. AAPH administration raised liver TBARS, but decreased plasma TBARS. Both plasma and liver TBARS were lower in APM group than control group before and after AAPH administration. Peroxyl radical trapping activity in plasma was elevated by APM feeding as compared to control group. APM was utilized as ascorbate, and was effective for prevention of oxidative stresses derived from AAPH by increasing plasma and liver ascorbate and plasma radical trapping activity.
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abstract  Effect of L-ascorbic acid phosphate magnesium (APM) on chicks injected radical initiator, 2, 2'-azobis(2-amidinopropane) dihydrochloride (AAPH), was examined. Chicks were fed APM as ascorbate resource for 7 days. Birds were administrated AAPH by intraperitoneal injection after APM feeding. The changes of ascorbate and thiobarbituric acid reactive substances (TBARS) in plasma and liver were determined before, and 3 and 6 hours after AAPH injection. Both plasma and liver ascorbate increased by APM feeding. After AAPH injection, liver ascorbate decreased, but plasma ascorbate increased in both control and APM-fed birds. AAPH administration raised liver TBARS, but decreased plasma TBARS. Both plasma and liver TBARS were lower in APM group than control group before and after AAPH administration. Peroxyl radical trapping activity in plasma was elevated by APM feeding as compared to control group. APM was utilized as ascorbate, and was effective for prevention of oxidative stresses derived from AAPH by increasing plasma and liver ascorbate and plasma radical trapping activity.
copIbaraki
pubJapan Science and Technology Agency
urlhttp://search.proquest.com/docview/1439290815/
doi10.2141/jpsa.39.179
pages179-184
date2002-07-01