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Development and in vitro proof-of-concept of interstitially targeted zinc- phthalocyanine liposomes for photodynamic therapy.

BACKGROUNDPhotodynamic therapy (PDT) has been successfully used to treat various solid tumors. However, some cancer types respond poorly to PDT, including urothelial carcinomas, nasopharyngeal carcinomas, and extrahepatic cholangiocarcinomas. The therapeutic recalcitrance is in part due to the use o... Full description

Journal Title: Current medicinal chemistry 2014, Vol.21(3), pp.377-391
Main Author: Broekgaarden, M
Other Authors: de Kroon, A I P M , Gulik, T M van , Heger, M
Format: Electronic Article Electronic Article
Language: English
Subjects:
ID: E-ISSN: 1875-533X
Link: http://search.proquest.com/docview/1469658202/?pq-origsite=primo
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recordid: proquest1469658202
title: Development and in vitro proof-of-concept of interstitially targeted zinc- phthalocyanine liposomes for photodynamic therapy.
format: Article
creator:
  • Broekgaarden, M
  • de Kroon, A I P M
  • Gulik, T M van
  • Heger, M
subjects:
  • Cell Line, Tumor–Administration & Dosage
  • Drug Delivery Systems–Pharmacology
  • Humans–Chemistry
  • Indoles–Drug Therapy
  • Liposomes–Metabolism
  • Neoplasms–Pathology
  • Organometallic Compounds–Administration & Dosage
  • Oxidation-Reduction–Pharmacology
  • Photochemotherapy–Drug Effects
  • Photosensitizing Agents–Methods
  • Reactive Oxygen Species–Administration & Dosage
  • Reactive Oxygen Species–Pharmacology
  • Reactive Oxygen Species–Metabolism
  • Indoles
  • Liposomes
  • Organometallic Compounds
  • Photosensitizing Agents
ispartof: Current medicinal chemistry, 2014, Vol.21(3), pp.377-391
description: BACKGROUNDPhotodynamic therapy (PDT) has been successfully used to treat various solid tumors. However, some cancer types respond poorly to PDT, including urothelial carcinomas, nasopharyngeal carcinomas, and extrahepatic cholangiocarcinomas. The therapeutic recalcitrance is in part due to the use of...
language: eng
source:
identifier: E-ISSN: 1875-533X
fulltext: fulltext
issn:
  • 1875533X
  • 1875-533X
url: Link


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titleDevelopment and in vitro proof-of-concept of interstitially targeted zinc- phthalocyanine liposomes for photodynamic therapy.
creatorBroekgaarden, M ; de Kroon, A I P M ; Gulik, T M van ; Heger, M
contributorBroekgaarden, M (correspondence author) ; Broekgaarden, M (record owner)
ispartofCurrent medicinal chemistry, 2014, Vol.21(3), pp.377-391
identifierE-ISSN: 1875-533X
subjectCell Line, Tumor–Administration & Dosage ; Drug Delivery Systems–Pharmacology ; Humans–Chemistry ; Indoles–Drug Therapy ; Liposomes–Metabolism ; Neoplasms–Pathology ; Organometallic Compounds–Administration & Dosage ; Oxidation-Reduction–Pharmacology ; Photochemotherapy–Drug Effects ; Photosensitizing Agents–Methods ; Reactive Oxygen Species–Administration & Dosage ; Reactive Oxygen Species–Pharmacology ; Reactive Oxygen Species–Metabolism ; Indoles ; Liposomes ; Organometallic Compounds ; Photosensitizing Agents
descriptionBACKGROUNDPhotodynamic therapy (PDT) has been successfully used to treat various solid tumors. However, some cancer types respond poorly to PDT, including urothelial carcinomas, nasopharyngeal carcinomas, and extrahepatic cholangiocarcinomas. The therapeutic recalcitrance is in part due to the use of...
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descriptionBACKGROUNDPhotodynamic therapy (PDT) has been successfully used to treat various solid tumors. However, some cancer types respond poorly to PDT, including urothelial carcinomas, nasopharyngeal carcinomas, and extrahepatic cholangiocarcinomas. The therapeutic recalcitrance is in part due to the use of...
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titleDevelopment and in vitro proof-of-concept of interstitially targeted zinc- phthalocyanine liposomes for photodynamic therapy.
authorBroekgaarden, M ; de Kroon, A I P M ; Gulik, T M van ; Heger, M
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abstractBACKGROUNDPhotodynamic therapy (PDT) has been successfully used to treat various solid tumors. However, some cancer types respond poorly to PDT, including urothelial carcinomas, nasopharyngeal carcinomas, and extrahepatic cholangiocarcinomas. The therapeutic recalcitrance is in part due to the use of...
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date2014-01-01