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Multiple control of fever production in the central nervous system of rabbits.

The effects of microinjection of prostaglandin D sub(2), E sub(2) and F sub(2 alpha ) and of endogenous pyrogen on the rectal temperature of rabbits were extensively examined in sixty-eight brain regions and in the third cerebral ventricle. Intracerebroventricular injection of both prostaglandins E... Full description

Journal Title: Journal of Physiology (London) 1988, Vol.397, pp.269-280
Main Author: Morimoto, A
Other Authors: Murakami, N , Nakamori, T , Watanabe, T
Format: Electronic Article Electronic Article
Language: English
Subjects:
Quelle: © ProQuest LLC All rights reserved
ID: ISSN: 0022-3751
Link: http://search.proquest.com/docview/14901286/
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title: Multiple control of fever production in the central nervous system of rabbits.
format: Article
creator:
  • Morimoto, A
  • Murakami, N
  • Nakamori, T
  • Watanabe, T
subjects:
  • Central Nervous System
  • Fever
  • Central Nervous System
  • Intracerebroventricular Administration
  • Effects on
  • Control
  • Production
  • Rabbits
  • Prostaglandins
  • Control
  • Effects on
  • Intracerebroventricular Administration
  • Production
  • Prostaglandins
  • Rabbits
ispartof: Journal of Physiology (London), 1988, Vol.397, pp.269-280
description: The effects of microinjection of prostaglandin D sub(2), E sub(2) and F sub(2 alpha ) and of endogenous pyrogen on the rectal temperature of rabbits were extensively examined in sixty-eight brain regions and in the third cerebral ventricle. Intracerebroventricular injection of both prostaglandins E sub(2) and F sub(2 alpha ) produced dose-dependent fever. The selective brain regions, the nucleus broca ventralis, preoptic area, anterior hypothalamus and the ventromedial hypothalamus, responded to microinjections of a small dose of prostaglandins E sub(2) and F sub(2 alpha ) by producing fever. The ventricular injection of endogenous pyrogen also produced fever. However, brain regions sensitive to microinjection of endogenous pyrogen were exclusively localized to regions near the organum vasculosum laminae terminalis (OVLT).
language: eng
source: © ProQuest LLC All rights reserved
identifier: ISSN: 0022-3751
fulltext: fulltext
issn:
  • 00223751
  • 0022-3751
url: Link


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titleMultiple control of fever production in the central nervous system of rabbits.
creatorMorimoto, A ; Murakami, N ; Nakamori, T ; Watanabe, T
contributorMorimoto, A (correspondence author)
ispartofJournal of Physiology (London), 1988, Vol.397, pp.269-280
identifierISSN: 0022-3751
subjectCentral Nervous System ; Fever ; Central Nervous System ; Intracerebroventricular Administration ; Effects on ; Control ; Production ; Rabbits ; Prostaglandins ; Control ; Effects on ; Intracerebroventricular Administration ; Production ; Prostaglandins ; Rabbits
descriptionThe effects of microinjection of prostaglandin D sub(2), E sub(2) and F sub(2 alpha ) and of endogenous pyrogen on the rectal temperature of rabbits were extensively examined in sixty-eight brain regions and in the third cerebral ventricle. Intracerebroventricular injection of both prostaglandins E sub(2) and F sub(2 alpha ) produced dose-dependent fever. The selective brain regions, the nucleus broca ventralis, preoptic area, anterior hypothalamus and the ventromedial hypothalamus, responded to microinjections of a small dose of prostaglandins E sub(2) and F sub(2 alpha ) by producing fever. The ventricular injection of endogenous pyrogen also produced fever. However, brain regions sensitive to microinjection of endogenous pyrogen were exclusively localized to regions near the organum vasculosum laminae terminalis (OVLT).
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abstractThe effects of microinjection of prostaglandin D sub(2), E sub(2) and F sub(2 alpha ) and of endogenous pyrogen on the rectal temperature of rabbits were extensively examined in sixty-eight brain regions and in the third cerebral ventricle. Intracerebroventricular injection of both prostaglandins E sub(2) and F sub(2 alpha ) produced dose-dependent fever. The selective brain regions, the nucleus broca ventralis, preoptic area, anterior hypothalamus and the ventromedial hypothalamus, responded to microinjections of a small dose of prostaglandins E sub(2) and F sub(2 alpha ) by producing fever. The ventricular injection of endogenous pyrogen also produced fever. However, brain regions sensitive to microinjection of endogenous pyrogen were exclusively localized to regions near the organum vasculosum laminae terminalis (OVLT).
urlhttp://search.proquest.com/docview/14901286/
date1988-01-01