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Ventromedial hypothalamus is highly sensitive to prostaglandin E sub(2) for producing fever in rabbits.

The febrile responses induced by intraventricular or intrapreoptic (bilateral) injections of prostaglandin E sub(2) (PGE sub(2)) were investigated in the same group of rabbits. Both injections produced dose-dependent fever over a range of 100-2000 ng. However the magnitude of febrile responses induc... Full description

Journal Title: Journal of Physiology (London) 1988, Vol.397, pp.259-268
Main Author: Morimoto, A
Other Authors: Murakami, N , Nakamori, T , Watanabe, T
Format: Electronic Article Electronic Article
Language: English
Subjects:
Quelle: © ProQuest LLC All rights reserved
ID: ISSN: 0022-3751
Link: http://search.proquest.com/docview/14914918/
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title: Ventromedial hypothalamus is highly sensitive to prostaglandin E sub(2) for producing fever in rabbits.
format: Article
creator:
  • Morimoto, A
  • Murakami, N
  • Nakamori, T
  • Watanabe, T
subjects:
  • Hypothalamus (Ventromedial)
  • Fever
  • Central Nervous System
  • Sensitivity
  • Production
  • Rabbits
  • Prostaglandin E2
  • Production
  • Prostaglandin E2
  • Rabbits
  • Sensitivity
ispartof: Journal of Physiology (London), 1988, Vol.397, pp.259-268
description: The febrile responses induced by intraventricular or intrapreoptic (bilateral) injections of prostaglandin E sub(2) (PGE sub(2)) were investigated in the same group of rabbits. Both injections produced dose-dependent fever over a range of 100-2000 ng. However the magnitude of febrile responses induced by ventricular injections was significantly greater than those by intrapreoptic injections. This indicates that there exist regions more sensitive to PGE sub(2) than the preoptic region for producing fever. The results showed that the preoptic and anterior hypothalamic region, and the ventromedial hypothalamic region are highly sensitive to PGE sub(2) for producing fever.
language: eng
source: © ProQuest LLC All rights reserved
identifier: ISSN: 0022-3751
fulltext: fulltext
issn:
  • 00223751
  • 0022-3751
url: Link


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titleVentromedial hypothalamus is highly sensitive to prostaglandin E sub(2) for producing fever in rabbits.
creatorMorimoto, A ; Murakami, N ; Nakamori, T ; Watanabe, T
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ispartofJournal of Physiology (London), 1988, Vol.397, pp.259-268
identifierISSN: 0022-3751
subjectHypothalamus (Ventromedial) ; Fever ; Central Nervous System ; Sensitivity ; Production ; Rabbits ; Prostaglandin E2 ; Production ; Prostaglandin E2 ; Rabbits ; Sensitivity
descriptionThe febrile responses induced by intraventricular or intrapreoptic (bilateral) injections of prostaglandin E sub(2) (PGE sub(2)) were investigated in the same group of rabbits. Both injections produced dose-dependent fever over a range of 100-2000 ng. However the magnitude of febrile responses induced by ventricular injections was significantly greater than those by intrapreoptic injections. This indicates that there exist regions more sensitive to PGE sub(2) than the preoptic region for producing fever. The results showed that the preoptic and anterior hypothalamic region, and the ventromedial hypothalamic region are highly sensitive to PGE sub(2) for producing fever.
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titleVentromedial hypothalamus is highly sensitive to prostaglandin E sub(2) for producing fever in rabbits.
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abstractThe febrile responses induced by intraventricular or intrapreoptic (bilateral) injections of prostaglandin E sub(2) (PGE sub(2)) were investigated in the same group of rabbits. Both injections produced dose-dependent fever over a range of 100-2000 ng. However the magnitude of febrile responses induced by ventricular injections was significantly greater than those by intrapreoptic injections. This indicates that there exist regions more sensitive to PGE sub(2) than the preoptic region for producing fever. The results showed that the preoptic and anterior hypothalamic region, and the ventromedial hypothalamic region are highly sensitive to PGE sub(2) for producing fever.
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date1988-01-01