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Integrated analysis of differential miRNA and mRNA expression profiles in human radioresistant and radiosensitive nasopharyngeal carcinoma cells.

BACKGROUNDThe purpose of this study was to identify miRNAs and genes involved in nasopharyngeal carcinoma (NPC) radioresistance, and explore the underlying mechanisms in the development of radioresistance. METHODSWe used microarrays to compare the differences of both miRNA and mRNA expression profil... Full description

Journal Title: PloS one 2014, Vol.9(1), p.e87767
Main Author: Li, Xin-Hui
Other Authors: Qu, Jia-Quan , Yi, Hong , Zhang, Peng-Fei , Yi, Hong-Mei , Wan, Xun-Xun , He, Qiu-Yan , Ye, Xu , Yuan, Li , Zhu, Jing-Feng , Li, Jiao-Yang , Xiao, Zhi-Qiang
Format: Electronic Article Electronic Article
Language: English
Subjects:
ID: E-ISSN: 1932-6203 ; DOI: 10.1371/journal.pone.0087767
Link: http://search.proquest.com/docview/1499124277/?pq-origsite=primo
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title: Integrated analysis of differential miRNA and mRNA expression profiles in human radioresistant and radiosensitive nasopharyngeal carcinoma cells.
format: Article
creator:
  • Li, Xin-Hui
  • Qu, Jia-Quan
  • Yi, Hong
  • Zhang, Peng-Fei
  • Yi, Hong-Mei
  • Wan, Xun-Xun
  • He, Qiu-Yan
  • Ye, Xu
  • Yuan, Li
  • Zhu, Jing-Feng
  • Li, Jiao-Yang
  • Xiao, Zhi-Qiang
subjects:
  • Carcinoma–Biosynthesis
  • Cell Line, Tumor–Genetics
  • Gene Expression Regulation, Neoplastic–Genetics
  • Humans–Metabolism
  • Micrornas–Pathology
  • Nasopharyngeal Carcinoma–Biosynthesis
  • Nasopharyngeal Neoplasms–Genetics
  • RNA, Messenger–Biosynthesis
  • RNA, Neoplasm–Genetics
  • Radiation Tolerance–Genetics
  • Micrornas
  • RNA, Messenger
  • RNA, Neoplasm
ispartof: PloS one, 2014, Vol.9(1), p.e87767
description: BACKGROUNDThe purpose of this study was to identify miRNAs and genes involved in nasopharyngeal carcinoma (NPC) radioresistance, and explore the underlying mechanisms in the development of radioresistance. METHODSWe used microarrays to compare the differences of both miRNA and mRNA expression profiles...
language: eng
source:
identifier: E-ISSN: 1932-6203 ; DOI: 10.1371/journal.pone.0087767
fulltext: fulltext
issn:
  • 19326203
  • 1932-6203
url: Link


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titleIntegrated analysis of differential miRNA and mRNA expression profiles in human radioresistant and radiosensitive nasopharyngeal carcinoma cells.
creatorLi, Xin-Hui ; Qu, Jia-Quan ; Yi, Hong ; Zhang, Peng-Fei ; Yi, Hong-Mei ; Wan, Xun-Xun ; He, Qiu-Yan ; Ye, Xu ; Yuan, Li ; Zhu, Jing-Feng ; Li, Jiao-Yang ; Xiao, Zhi-Qiang
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identifierE-ISSN: 1932-6203 ; DOI: 10.1371/journal.pone.0087767
subjectCarcinoma–Biosynthesis ; Cell Line, Tumor–Genetics ; Gene Expression Regulation, Neoplastic–Genetics ; Humans–Metabolism ; Micrornas–Pathology ; Nasopharyngeal Carcinoma–Biosynthesis ; Nasopharyngeal Neoplasms–Genetics ; RNA, Messenger–Biosynthesis ; RNA, Neoplasm–Genetics ; Radiation Tolerance–Genetics ; Micrornas ; RNA, Messenger ; RNA, Neoplasm
descriptionBACKGROUNDThe purpose of this study was to identify miRNAs and genes involved in nasopharyngeal carcinoma (NPC) radioresistance, and explore the underlying mechanisms in the development of radioresistance. METHODSWe used microarrays to compare the differences of both miRNA and mRNA expression profiles...
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titleIntegrated analysis of differential miRNA and mRNA expression profiles in human radioresistant and radiosensitive nasopharyngeal carcinoma cells.
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titleIntegrated analysis of differential miRNA and mRNA expression profiles in human radioresistant and radiosensitive nasopharyngeal carcinoma cells.
authorLi, Xin-Hui ; Qu, Jia-Quan ; Yi, Hong ; Zhang, Peng-Fei ; Yi, Hong-Mei ; Wan, Xun-Xun ; He, Qiu-Yan ; Ye, Xu ; Yuan, Li ; Zhu, Jing-Feng ; Li, Jiao-Yang ; Xiao, Zhi-Qiang
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abstractBACKGROUNDThe purpose of this study was to identify miRNAs and genes involved in nasopharyngeal carcinoma (NPC) radioresistance, and explore the underlying mechanisms in the development of radioresistance. METHODSWe used microarrays to compare the differences of both miRNA and mRNA expression profiles...
doi10.1371/journal.pone.0087767
urlhttp://search.proquest.com/docview/1499124277/
date2014-01-01