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Reduced expression of uroplakin 1A is associated with the poor prognosis of gastric adenocarcinoma patients.

BACKGROUNDThe aim of this study was to investigate the expression and prognostic significance of Uroplakin1A (UPK1A) in gastric adenocarcinoma patients. Functional studies were also analyzed in vitro. METHODOLOGY/PRINCIPAL FINDINGSReal-time quantitative PCR (RT-qPCR), western blotting, and immunohis... Full description

Journal Title: PloS one 2014, Vol.9(4), p.e93073
Main Author: Zheng, Yan
Other Authors: Wang, Dan-Dan , Wang, Wei , Pan, Ke , Huang, Chun-Yu , Li, Yuan-Fang , Wang, Qi-Jing , Yuan, Shu-Qiang , Jiang, Shan-Shan , Qiu, Hai-Bo , Chen, Yong-Ming , Zhang, Xiao-Fei , Zhao, Bai-Wei , Mai, Cong , Xia, Jian-Chuan , Zhou, Zhi-Wei
Format: Electronic Article Electronic Article
Language: English
Subjects:
ID: E-ISSN: 1932-6203 ; DOI: 10.1371/journal.pone.0093073
Link: http://search.proquest.com/docview/1513051542/?pq-origsite=primo
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title: Reduced expression of uroplakin 1A is associated with the poor prognosis of gastric adenocarcinoma patients.
format: Article
creator:
  • Zheng, Yan
  • Wang, Dan-Dan
  • Wang, Wei
  • Pan, Ke
  • Huang, Chun-Yu
  • Li, Yuan-Fang
  • Wang, Qi-Jing
  • Yuan, Shu-Qiang
  • Jiang, Shan-Shan
  • Qiu, Hai-Bo
  • Chen, Yong-Ming
  • Zhang, Xiao-Fei
  • Zhao, Bai-Wei
  • Mai, Cong
  • Xia, Jian-Chuan
  • Zhou, Zhi-Wei
subjects:
  • Adenocarcinoma–Metabolism
  • Apoptosis–Mortality
  • Blotting, Western–Secondary
  • Cell Adhesion–Metabolism
  • Cell Cycle–Genetics
  • Cell Movement–Metabolism
  • Cell Proliferation–Mortality
  • Female–Pathology
  • Gastric Mucosa–Genetics
  • Humans–Metabolism
  • Immunoenzyme Techniques–Metabolism
  • Lymphatic Metastasis–Metabolism
  • Male–Metabolism
  • RNA, Messenger–Metabolism
  • Real-Time Polymerase Chain Reaction–Metabolism
  • Reverse Transcriptase Polymerase Chain Reaction–Metabolism
  • Stomach Neoplasms–Metabolism
  • Tumor Cells, Cultured–Metabolism
  • Uroplakin Ia–Metabolism
  • RNA, Messenger
  • Upk1a Protein, Human
  • Uroplakin Ia
ispartof: PloS one, 2014, Vol.9(4), p.e93073
description: BACKGROUNDThe aim of this study was to investigate the expression and prognostic significance of Uroplakin1A (UPK1A) in gastric adenocarcinoma patients. Functional studies were also analyzed in vitro. METHODOLOGY/PRINCIPAL FINDINGSReal-time quantitative PCR (RT-qPCR), western blotting, and immunohistochemical...
language: eng
source:
identifier: E-ISSN: 1932-6203 ; DOI: 10.1371/journal.pone.0093073
fulltext: fulltext
issn:
  • 19326203
  • 1932-6203
url: Link


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titleReduced expression of uroplakin 1A is associated with the poor prognosis of gastric adenocarcinoma patients.
creatorZheng, Yan ; Wang, Dan-Dan ; Wang, Wei ; Pan, Ke ; Huang, Chun-Yu ; Li, Yuan-Fang ; Wang, Qi-Jing ; Yuan, Shu-Qiang ; Jiang, Shan-Shan ; Qiu, Hai-Bo ; Chen, Yong-Ming ; Zhang, Xiao-Fei ; Zhao, Bai-Wei ; Mai, Cong ; Xia, Jian-Chuan ; Zhou, Zhi-Wei
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ispartofPloS one, 2014, Vol.9(4), p.e93073
identifierE-ISSN: 1932-6203 ; DOI: 10.1371/journal.pone.0093073
subjectAdenocarcinoma–Metabolism ; Apoptosis–Mortality ; Blotting, Western–Secondary ; Cell Adhesion–Metabolism ; Cell Cycle–Genetics ; Cell Movement–Metabolism ; Cell Proliferation–Mortality ; Female–Pathology ; Gastric Mucosa–Genetics ; Humans–Metabolism ; Immunoenzyme Techniques–Metabolism ; Lymphatic Metastasis–Metabolism ; Male–Metabolism ; RNA, Messenger–Metabolism ; Real-Time Polymerase Chain Reaction–Metabolism ; Reverse Transcriptase Polymerase Chain Reaction–Metabolism ; Stomach Neoplasms–Metabolism ; Tumor Cells, Cultured–Metabolism ; Uroplakin Ia–Metabolism ; RNA, Messenger ; Upk1a Protein, Human ; Uroplakin Ia
descriptionBACKGROUNDThe aim of this study was to investigate the expression and prognostic significance of Uroplakin1A (UPK1A) in gastric adenocarcinoma patients. Functional studies were also analyzed in vitro. METHODOLOGY/PRINCIPAL FINDINGSReal-time quantitative PCR (RT-qPCR), western blotting, and immunohistochemical...
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titleReduced expression of uroplakin 1A is associated with the poor prognosis of gastric adenocarcinoma patients.
descriptionBACKGROUNDThe aim of this study was to investigate the expression and prognostic significance of Uroplakin1A (UPK1A) in gastric adenocarcinoma patients. Functional studies were also analyzed in vitro. METHODOLOGY/PRINCIPAL FINDINGSReal-time quantitative PCR (RT-qPCR), western blotting, and immunohistochemical...
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titleReduced expression of uroplakin 1A is associated with the poor prognosis of gastric adenocarcinoma patients.
authorZheng, Yan ; Wang, Dan-Dan ; Wang, Wei ; Pan, Ke ; Huang, Chun-Yu ; Li, Yuan-Fang ; Wang, Qi-Jing ; Yuan, Shu-Qiang ; Jiang, Shan-Shan ; Qiu, Hai-Bo ; Chen, Yong-Ming ; Zhang, Xiao-Fei ; Zhao, Bai-Wei ; Mai, Cong ; Xia, Jian-Chuan ; Zhou, Zhi-Wei
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abstractBACKGROUNDThe aim of this study was to investigate the expression and prognostic significance of Uroplakin1A (UPK1A) in gastric adenocarcinoma patients. Functional studies were also analyzed in vitro. METHODOLOGY/PRINCIPAL FINDINGSReal-time quantitative PCR (RT-qPCR), western blotting, and immunohistochemical...
doi10.1371/journal.pone.0093073
urlhttp://search.proquest.com/docview/1513051542/
date2014-01-01