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Cis-regulatory elements are harbored in Intron5 of the RUNX1 gene.

BACKGROUNDHuman RUNX1 gene is one of the most frequent target for chromosomal translocations associated with acute myeloid leukemia (AML) and acute lymphoid leukemia (ALL). The highest prevalence in AML is noted with (8; 21) translocation; which represents 12 to 15% of all AML cases. Interestingly,... Full description

Journal Title: BMC genomics March 24, 2014, Vol.15, p.225
Main Author: Rebolledo-Jaramillo, Boris
Other Authors: Alarcon, Ricardo A , Fernandez, Valentina I , Gutierrez, Soraya E
Format: Electronic Article Electronic Article
Language: English
Subjects:
ID: E-ISSN: 1471-2164 ; DOI: 10.1186/1471-2164-15-225
Link: http://search.proquest.com/docview/1516399935/?pq-origsite=primo
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title: Cis-regulatory elements are harbored in Intron5 of the RUNX1 gene.
format: Article
creator:
  • Rebolledo-Jaramillo, Boris
  • Alarcon, Ricardo A
  • Fernandez, Valentina I
  • Gutierrez, Soraya E
subjects:
  • Animals–Genetics
  • Chromosomes, Human, Pair 21–Metabolism
  • Chromosomes, Human, Pair 8–Chemistry
  • Core Binding Factor Alpha 2 Subunit–Metabolism
  • Deoxyribonuclease I–Genetics
  • HL-60 Cells–Genetics
  • Hela Cells–Genetics
  • Hep G2 Cells–Genetics
  • Humans–Genetics
  • Introns–Genetics
  • Jurkat Cells–Genetics
  • Mice–Genetics
  • Promoter Regions, Genetic–Genetics
  • Rats–Genetics
  • Regulatory Sequences, Nucleic Acid–Genetics
  • Translocation, Genetic–Genetics
  • Core Binding Factor Alpha 2 Subunit
  • Deoxyribonuclease I
ispartof: BMC genomics, March 24, 2014, Vol.15, p.225
description: BACKGROUNDHuman RUNX1 gene is one of the most frequent target for chromosomal translocations associated with acute myeloid leukemia (AML) and acute lymphoid leukemia (ALL). The highest prevalence in AML is noted with (8; 21) translocation; which represents 12 to 15% of all AML cases. Interestingly, all...
language: eng
source:
identifier: E-ISSN: 1471-2164 ; DOI: 10.1186/1471-2164-15-225
fulltext: fulltext
issn:
  • 14712164
  • 1471-2164
url: Link


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titleCis-regulatory elements are harbored in Intron5 of the RUNX1 gene.
creatorRebolledo-Jaramillo, Boris ; Alarcon, Ricardo A ; Fernandez, Valentina I ; Gutierrez, Soraya E
contributorRebolledo-Jaramillo, Boris (correspondence author) ; Rebolledo-Jaramillo, Boris (record owner)
ispartofBMC genomics, March 24, 2014, Vol.15, p.225
identifierE-ISSN: 1471-2164 ; DOI: 10.1186/1471-2164-15-225
subjectAnimals–Genetics ; Chromosomes, Human, Pair 21–Metabolism ; Chromosomes, Human, Pair 8–Chemistry ; Core Binding Factor Alpha 2 Subunit–Metabolism ; Deoxyribonuclease I–Genetics ; HL-60 Cells–Genetics ; Hela Cells–Genetics ; Hep G2 Cells–Genetics ; Humans–Genetics ; Introns–Genetics ; Jurkat Cells–Genetics ; Mice–Genetics ; Promoter Regions, Genetic–Genetics ; Rats–Genetics ; Regulatory Sequences, Nucleic Acid–Genetics ; Translocation, Genetic–Genetics ; Core Binding Factor Alpha 2 Subunit ; Deoxyribonuclease I
descriptionBACKGROUNDHuman RUNX1 gene is one of the most frequent target for chromosomal translocations associated with acute myeloid leukemia (AML) and acute lymphoid leukemia (ALL). The highest prevalence in AML is noted with (8; 21) translocation; which represents 12 to 15% of all AML cases. Interestingly, all...
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titleCis-regulatory elements are harbored in Intron5 of the RUNX1 gene.
descriptionBACKGROUNDHuman RUNX1 gene is one of the most frequent target for chromosomal translocations associated with acute myeloid leukemia (AML) and acute lymphoid leukemia (ALL). The highest prevalence in AML is noted with (8; 21) translocation; which represents 12 to 15% of all AML cases. Interestingly, all...
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titleCis-regulatory elements are harbored in Intron5 of the RUNX1 gene.
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abstractBACKGROUNDHuman RUNX1 gene is one of the most frequent target for chromosomal translocations associated with acute myeloid leukemia (AML) and acute lymphoid leukemia (ALL). The highest prevalence in AML is noted with (8; 21) translocation; which represents 12 to 15% of all AML cases. Interestingly, all...
doi10.1186/1471-2164-15-225
urlhttp://search.proquest.com/docview/1516399935/
issue1
date2014-03-24