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Procalcitonin algorithm in critically ill adults with undifferentiated infection or suspected sepsis. A randomized controlled trial.

RATIONALEThe role of procalcitonin (PCT), a widely used sepsis biomarker, in critically ill patients with sepsis is undetermined. OBJECTIVESTo investigate the effect of a low PCT cut-off on antibiotic prescription and to describe the relationships between PCT plasma concentration and sepsis severity... Full description

Journal Title: American journal of respiratory and critical care medicine November 15, 2014, Vol.190(10), pp.1102-1110
Main Author: Shehabi, Yahya
Other Authors: Sterba, Martin , Garrett, Peter Maxwell , Rachakonda, Kanaka Sundaram , Stephens, Dianne , Harrigan, Peter , Walker, Alison , Bailey, Michael J , Johnson, Bronwyn , Millis, David , Ding, Geoff , Peake, Sandra , Wong, Helen , Thomas, Jane , Smith, Kate , Forbes, Loretta , Hardie, Miranda , Micallef, Sharon , Fraser, John F , Shehabi
Format: Electronic Article Electronic Article
Language: English
Subjects:
ID: E-ISSN: 1535-4970 ; DOI: 10.1164/rccm.201408-1483OC
Link: http://search.proquest.com/docview/1625340194/?pq-origsite=primo
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title: Procalcitonin algorithm in critically ill adults with undifferentiated infection or suspected sepsis. A randomized controlled trial.
format: Article
creator:
  • Shehabi, Yahya
  • Sterba, Martin
  • Garrett, Peter Maxwell
  • Rachakonda, Kanaka Sundaram
  • Stephens, Dianne
  • Harrigan, Peter
  • Walker, Alison
  • Bailey, Michael J
  • Johnson, Bronwyn
  • Millis, David
  • Ding, Geoff
  • Peake, Sandra
  • Wong, Helen
  • Thomas, Jane
  • Smith, Kate
  • Forbes, Loretta
  • Hardie, Miranda
  • Micallef, Sharon
  • Fraser, John F
  • Shehabi
subjects:
  • Adult–Therapeutic Use
  • Aged–Blood
  • Algorithms–Blood
  • Anti-Bacterial Agents–Blood
  • Australia–Blood
  • Biomarkers–Drug Therapy
  • Calcitonin–Mortality
  • Calcitonin Gene-Related Peptide–Mortality
  • Critical Care–Mortality
  • Critical Illness–Mortality
  • Drug Administration Schedule–Mortality
  • Female–Mortality
  • Humans–Mortality
  • Male–Mortality
  • Middle Aged–Mortality
  • Predictive Value of Tests–Mortality
  • Prognosis–Mortality
  • Prospective Studies–Mortality
  • Protein Precursors–Mortality
  • Sepsis
ispartof: American journal of respiratory and critical care medicine, November 15, 2014, Vol.190(10), pp.1102-1110
description: RATIONALEThe role of procalcitonin (PCT), a widely used sepsis biomarker, in critically ill patients with sepsis is undetermined. OBJECTIVESTo investigate the effect of a low PCT cut-off on antibiotic prescription and to describe the relationships between PCT plasma concentration and sepsis severity...
language: eng
source:
identifier: E-ISSN: 1535-4970 ; DOI: 10.1164/rccm.201408-1483OC
fulltext: fulltext
issn:
  • 15354970
  • 1535-4970
url: Link


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titleProcalcitonin algorithm in critically ill adults with undifferentiated infection or suspected sepsis. A randomized controlled trial.
creatorShehabi, Yahya ; Sterba, Martin ; Garrett, Peter Maxwell ; Rachakonda, Kanaka Sundaram ; Stephens, Dianne ; Harrigan, Peter ; Walker, Alison ; Bailey, Michael J ; Johnson, Bronwyn ; Millis, David ; Ding, Geoff ; Peake, Sandra ; Wong, Helen ; Thomas, Jane ; Smith, Kate ; Forbes, Loretta ; Hardie, Miranda ; Micallef, Sharon ; Fraser, John F ; Shehabi
contributorSmith, Kate (correspondence author) ; Cheng, Roann (record owner) ; Howe, Belinda ; Bailey, Michael ; Obrien, Rita ; Millis, David ; Wong, Helen ; Janu, Margaret ; Ihle, Benno ; Pather, Vasantha ; Robertson, Megan ; Harrigan, Peter ; Hardie, Miranda ; Pollock, Emma ; Rachakonda, Kanaka Sundaram ; Micallef, Sharon ; Ketchley, Imogen ; Srinivasan, Saradha ; Garrett, Peter Maxwell ; Forbes
ispartofAmerican journal of respiratory and critical care medicine, November 15, 2014, Vol.190(10), pp.1102-1110
identifierE-ISSN: 1535-4970 ; DOI: 10.1164/rccm.201408-1483OC
subjectAdult–Therapeutic Use ; Aged–Blood ; Algorithms–Blood ; Anti-Bacterial Agents–Blood ; Australia–Blood ; Biomarkers–Drug Therapy ; Calcitonin–Mortality ; Calcitonin Gene-Related Peptide–Mortality ; Critical Care–Mortality ; Critical Illness–Mortality ; Drug Administration Schedule–Mortality ; Female–Mortality ; Humans–Mortality ; Male–Mortality ; Middle Aged–Mortality ; Predictive Value of Tests–Mortality ; Prognosis–Mortality ; Prospective Studies–Mortality ; Protein Precursors–Mortality ; Sepsis
descriptionRATIONALEThe role of procalcitonin (PCT), a widely used sepsis biomarker, in critically ill patients with sepsis is undetermined. OBJECTIVESTo investigate the effect of a low PCT cut-off on antibiotic prescription and to describe the relationships between PCT plasma concentration and sepsis severity...
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titleProcalcitonin algorithm in critically ill adults with undifferentiated infection or suspected sepsis. A randomized controlled trial.
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titleProcalcitonin algorithm in critically ill adults with undifferentiated infection or suspected sepsis. A randomized controlled trial.
authorShehabi, Yahya ; Sterba, Martin ; Garrett, Peter Maxwell ; Rachakonda, Kanaka Sundaram ; Stephens, Dianne ; Harrigan, Peter ; Walker, Alison ; Bailey, Michael J ; Johnson, Bronwyn ; Millis, David ; Ding, Geoff ; Peake, Sandra ; Wong, Helen ; Thomas, Jane ; Smith, Kate ; Forbes, Loretta ; Hardie, Miranda...
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atitleProcalcitonin algorithm in critically ill adults with undifferentiated infection or suspected sepsis. A randomized controlled trial.
jtitleAmerican journal of respiratory and critical care medicine
risdate20141115
volume190
issue10
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pages1102-1110
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abstractRATIONALEThe role of procalcitonin (PCT), a widely used sepsis biomarker, in critically ill patients with sepsis is undetermined. OBJECTIVESTo investigate the effect of a low PCT cut-off on antibiotic prescription and to describe the relationships between PCT plasma concentration and sepsis severity...
doi10.1164/rccm.201408-1483OC
urlhttp://search.proquest.com/docview/1625340194/
issn1073449X
date2014-11-15