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Trimodality imaging system and intravascular endoscopic probe: combined optical coherence tomography, fluorescence imaging and ultrasound imaging.

In this Letter, we present a trimodality imaging system and an intravascular endoscopic probe for the detection of early-stage atherosclerotic plaques. The integrated system is able to acquire optical coherence tomography (OCT), fluorescence, and ultrasound images and simultaneously display them in... Full description

Journal Title: Optics letters December 1, 2014, Vol.39(23), pp.6652-6655
Main Author: Liang, Shanshan
Other Authors: Ma, Teng , Jing, Joseph , Li, Xiang , Li, Jiawen , Shung, K Kirk , Zhou, Qifa , Zhang, Jun , Chen, Zhongping
Format: Electronic Article Electronic Article
Language: English
Subjects:
ID: E-ISSN: 1539-4794 ; DOI: 10.1364/OL.39.006652
Link: http://search.proquest.com/docview/1635010340/?pq-origsite=primo
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title: Trimodality imaging system and intravascular endoscopic probe: combined optical coherence tomography, fluorescence imaging and ultrasound imaging.
format: Article
creator:
  • Liang, Shanshan
  • Ma, Teng
  • Jing, Joseph
  • Li, Xiang
  • Li, Jiawen
  • Shung, K Kirk
  • Zhou, Qifa
  • Zhang, Jun
  • Chen, Zhongping
subjects:
  • Animals–Diagnostic Imaging
  • Coronary Vessels–Instrumentation
  • Endoscopy–Instrumentation
  • Humans–Diagnostic Imaging
  • Multimodal Imaging–Instrumentation
  • Plaque, Atherosclerotic–Instrumentation
  • Rabbits–Instrumentation
  • Tomography, Optical Coherence–Instrumentation
  • Ultrasonography–Instrumentation
ispartof: Optics letters, December 1, 2014, Vol.39(23), pp.6652-6655
description: In this Letter, we present a trimodality imaging system and an intravascular endoscopic probe for the detection of early-stage atherosclerotic plaques. The integrated system is able to acquire optical coherence tomography (OCT), fluorescence, and ultrasound images and simultaneously display them in real time. A trimodality intravascular endoscopic probe of 1.2 mm in diameter and 7 mm in length was fabricated based on a dual-modality optical probe that integrates OCT and fluorescence imaging functions and a miniature ultrasound transducer. The probe is capable of rotating at up to 600 rpm. Ex vivo images from rabbit aorta and human coronary arteries showed that this combined system is capable of providing high resolution, deep penetration depth and specific molecular fluorescence contrast simultaneously.
language: eng
source:
identifier: E-ISSN: 1539-4794 ; DOI: 10.1364/OL.39.006652
fulltext: fulltext
issn:
  • 15394794
  • 1539-4794
url: Link


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titleTrimodality imaging system and intravascular endoscopic probe: combined optical coherence tomography, fluorescence imaging and ultrasound imaging.
creatorLiang, Shanshan ; Ma, Teng ; Jing, Joseph ; Li, Xiang ; Li, Jiawen ; Shung, K Kirk ; Zhou, Qifa ; Zhang, Jun ; Chen, Zhongping
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ispartofOptics letters, December 1, 2014, Vol.39(23), pp.6652-6655
identifierE-ISSN: 1539-4794 ; DOI: 10.1364/OL.39.006652
subjectAnimals–Diagnostic Imaging ; Coronary Vessels–Instrumentation ; Endoscopy–Instrumentation ; Humans–Diagnostic Imaging ; Multimodal Imaging–Instrumentation ; Plaque, Atherosclerotic–Instrumentation ; Rabbits–Instrumentation ; Tomography, Optical Coherence–Instrumentation ; Ultrasonography–Instrumentation
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descriptionIn this Letter, we present a trimodality imaging system and an intravascular endoscopic probe for the detection of early-stage atherosclerotic plaques. The integrated system is able to acquire optical coherence tomography (OCT), fluorescence, and ultrasound images and simultaneously display them in real time. A trimodality intravascular endoscopic probe of 1.2 mm in diameter and 7 mm in length was fabricated based on a dual-modality optical probe that integrates OCT and fluorescence imaging functions and a miniature ultrasound transducer. The probe is capable of rotating at up to 600 rpm. Ex vivo images from rabbit aorta and human coronary arteries showed that this combined system is capable of providing high resolution, deep penetration depth and specific molecular fluorescence contrast simultaneously.
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