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Randomized assessment of rapid endovascular treatment of ischemic stroke.

BACKGROUNDAmong patients with a proximal vessel occlusion in the anterior circulation, 60 to 80% of patients die within 90 days after stroke onset or do not regain functional independence despite alteplase treatment. We evaluated rapid endovascular treatment in addition to standard care in patients... Full description

Journal Title: The New England journal of medicine March 12, 2015, Vol.372(11), pp.1019-1030
Main Author: Goyal, Mayank
Other Authors: Demchuk, Andrew M , Menon, Bijoy K , Eesa, Muneer , Rempel, Jeremy L , Thornton, John , Roy, Daniel , Jovin, Tudor G , Willinsky, Robert A , Sapkota, Biggya L , Dowlatshahi, Dar , Frei, Donald F , Kamal, Noreen R , Montanera, Walter J , Poppe, Alexandre Y , Ryckborst, Karla J , Silver, Frank L , Shuaib, Ashfaq , Tampieri, Donatella , Williams, David , Bang, Oh Young , Baxter, Blaise W , Burns, Paul A , Choe, Hana , Heo, Ji-Hoe , Holmstedt, Christine A , Jankowitz, Brian , Kelly, Michael , Linares, Guillermo , Mandzia, Jennifer L , Shankar, Jai , Sohn, Sung-Il , Swartz, Richard H , Barber, Philip A , Coutts, Shelagh B , Smith, Eric E , Morrish, William F , Weill, Alain , Subramaniam, Suresh , Mitha, Alim P , Wong, John H , Lowerison, Mark W , Sajobi, Tolulope T , Hill, Michael D , Goyal, Mayank
Format: Electronic Article Electronic Article
Language: English
Subjects:
ID: E-ISSN: 1533-4406 ; DOI: 10.1056/NEJMoa1414905
Link: http://search.proquest.com/docview/1663657444/?pq-origsite=primo
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title: Randomized assessment of rapid endovascular treatment of ischemic stroke.
format: Article
creator:
  • Goyal, Mayank
  • Demchuk, Andrew M
  • Menon, Bijoy K
  • Eesa, Muneer
  • Rempel, Jeremy L
  • Thornton, John
  • Roy, Daniel
  • Jovin, Tudor G
  • Willinsky, Robert A
  • Sapkota, Biggya L
  • Dowlatshahi, Dar
  • Frei, Donald F
  • Kamal, Noreen R
  • Montanera, Walter J
  • Poppe, Alexandre Y
  • Ryckborst, Karla J
  • Silver, Frank L
  • Shuaib, Ashfaq
  • Tampieri, Donatella
  • Williams, David
  • Bang, Oh Young
  • Baxter, Blaise W
  • Burns, Paul A
  • Choe, Hana
  • Heo, Ji-Hoe
  • Holmstedt, Christine A
  • Jankowitz, Brian
  • Kelly, Michael
  • Linares, Guillermo
  • Mandzia, Jennifer L
  • Shankar, Jai
  • Sohn, Sung-Il
  • Swartz, Richard H
  • Barber, Philip A
  • Coutts, Shelagh B
  • Smith, Eric E
  • Morrish, William F
  • Weill, Alain
  • Subramaniam, Suresh
  • Mitha, Alim P
  • Wong, John H
  • Lowerison, Mark W
  • Sajobi, Tolulope T
  • Hill, Michael D
  • Goyal, Mayank
subjects:
  • Aged–Diagnostic Imaging
  • Aged, 80 and Over–Therapy
  • Angiography, Digital Subtraction–Chemically Induced
  • Brain Ischemia–Therapeutic Use
  • Cerebral Hemorrhage–Mortality
  • Combined Modality Therapy–Therapy
  • Endovascular Procedures–Instrumentation
  • Female–Therapeutic Use
  • Fibrinolytic Agents–Therapeutic Use
  • Humans–Therapeutic Use
  • Intention to Treat Analysis–Therapeutic Use
  • Male–Therapeutic Use
  • Middle Aged–Therapeutic Use
  • Reperfusion–Therapeutic Use
  • Single-Blind Method–Therapeutic Use
  • Stents–Therapeutic Use
  • Stroke–Therapeutic Use
  • Thrombectomy–Therapeutic Use
  • Tissue Plasminogen Activator–Therapeutic Use
  • Tomography, X-Ray Computed–Therapeutic Use
  • Abridged
  • Fibrinolytic Agents
  • Tissue Plasminogen Activator
ispartof: The New England journal of medicine, March 12, 2015, Vol.372(11), pp.1019-1030
description: BACKGROUNDAmong patients with a proximal vessel occlusion in the anterior circulation, 60 to 80% of patients die within 90 days after stroke onset or do not regain functional independence despite alteplase treatment. We evaluated rapid endovascular treatment in addition to standard care in patients with...
language: eng
source:
identifier: E-ISSN: 1533-4406 ; DOI: 10.1056/NEJMoa1414905
fulltext: fulltext
issn:
  • 15334406
  • 1533-4406
url: Link


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titleRandomized assessment of rapid endovascular treatment of ischemic stroke.
creatorGoyal, Mayank ; Demchuk, Andrew M ; Menon, Bijoy K ; Eesa, Muneer ; Rempel, Jeremy L ; Thornton, John ; Roy, Daniel ; Jovin, Tudor G ; Willinsky, Robert A ; Sapkota, Biggya L ; Dowlatshahi, Dar ; Frei, Donald F ; Kamal, Noreen R ; Montanera, Walter J ; Poppe, Alexandre Y ; Ryckborst, Karla J ; Silver, Frank L ; Shuaib, Ashfaq ; Tampieri, Donatella ; Williams, David ; Bang, Oh Young ; Baxter, Blaise W ; Burns, Paul A ; Choe, Hana ; Heo, Ji-Hoe ; Holmstedt, Christine A ; Jankowitz, Brian ; Kelly, Michael ; Linares, Guillermo ; Mandzia, Jennifer L ; Shankar, Jai ; Sohn, Sung-Il ; Swartz, Richard H ; Barber, Philip A ; Coutts, Shelagh B ; Smith, Eric E ; Morrish, William F ; Weill, Alain ; Subramaniam, Suresh ; Mitha, Alim P ; Wong, John H ; Lowerison, Mark W ; Sajobi, Tolulope T ; Hill, Michael D ; Goyal, Mayank
contributorHill, M D (correspondence author) ; Goyal, M (record owner) ; Demchuk, A M ; Menon, B K ; Eesa, M ; Ryckborst, K J ; Wright, M R ; Kamal, N R ; Andersen, L ; Randhawa, P A ; Stewart, T ; Patil, S ; Minhas, P ; Almekhlafi, M ; Mishra, S ; Clement, F ; Sajobi, T ; Hill, M D ; Goyal, M ; Demchuk, A M ; Menon, B K ; Shuaib, A ; Montanera, W J ; Roy, D ; Silver, F L ; Jovin, T G ; Frei, D F ; Sapkota, B ; Rempel, J L ; Thornton, J ; Williams, D ; Tampieri, D ; Poppe, A Y ; Dowlatshahi, D ; Ryckborst, K J ; Kamal, N R ; Goyal, M ; Wong, J H ; Mitha, A P ; Subramaniam, S ; Hull, G ; Lowerison, M W ; Sajobi, T ; Salluzzi, M ; Wright, M R ; Maxwell, M ; Lacusta, S ; Drupals, E ; Armitage, K ; Barber, P A ; Smith, E E ; Morrish, W F ; Coutts, S B ; Derdeyn, C ; Demaerschalk, B ; Yavagil, D ; Martin, R ; Brant, R ; Yu, Y ; Willinsky, R A ; Montanera, W J ; Roy, D ; Weill, A ; Hill, M D ; Goyal, M ; Ryckborst, K J ; Kenney, C ; Aram, H ; Stewart, T ; Demchuk, A M ; Coutts, S B ; Menon, B K ; Subramaniam, S ; Barber, P A ; Smith, E E ; Stys, P K ; Watson, T W ; Klein, G ; Pearson, D ; Couillard, P ; Trivedi, A ; Singh, D ; Klourfeld, E ; Yu, Y ; Imoukhuede, O ; Nikneshan, D ; Blayney, S ; Reddy, R ; Choi, P ; Horton, M ; Musuka, T ; Dubuc, V ; Field, T S ; Desai, J ; Adatia, S ; Alseraya, A ; Nambiar, V ; Mishra, S ; Almekhlafi, M ; van Dijk, R ; Wong, J H ; Mitha, A P ; Morrish, W F ; Eesa, M ; Newcommon, N J ; Shuaib, A ; Rempel, J L ; Schwindt, B ; Butcher, K ; Jeerakathil, T ; Buck, B ; Khan, K ; Naik, S S ; Emery, D J ; Owen, R J ; Kotylak, T B ; Ashforth, R A ; Yeo, T A ; Mcnally, D ; Siddiqui, M ; Saqqur, M ; Hussain, D ; Kalashyan, H ; Manosalva, A ; Kate, M ; Gioia, L ; Hasan, S ; Mohammad, A ; Muratoglu, M ; Williams, D ; Thornton, J ; Cullen, A ; Brennan, P ; Hare, A O ; Looby, S ; Hyland, D ; Cullen, A ; Duff, S ; Mc Cusker, M ; Hallinan, B ; Lee, S ; Mc Cormack, J ; Moore, A ; O'Connor, M ; Donegan, C ; Brewer, L ; Martin, A ; Murphy, S ; O'Rourke, K ; Smyth, S ; Kelly, P ; Lynch, T ; Daly, T ; O'Brien, P ; O'Driscoll, A ; Martin, M ; Daly, T ; Collins, R ; Coughlan, T ; Mccabe, D ; Murphy, S ; O'Neill, D ; Mulroy, M ; Lynch, O ; Walsh, T ; O'Donnell, M ; Galvin, T ; Harbison, J ; Mcelwaine, P ; Mulpeter, K ; Mcloughlin, C ; Reardon, M ; Harkin, E ; Dolan, E ; Watts, M ; Cunningham, N ; Fallon, C ; Gallagher, S ; Cotter, P ; Crowe, M ; Doyle, R ; Noone, I ; Poppe, A Y ; Roy, D ; Lapierre, M ; Coté, V A ; Lanthier, S ; Odier, C ; Durocher, A ; Raymond, J ; Weill, A ; Daneault, N ; Deschaintre, Y ; Jovin, T ; Jankowitz, B ; Baxendell, L ; Massaro, L ; Jackson-Graves, C ; Decesare, S ; Porter, P ; Armbruster, K ; Adams, A ; Billigan, J ; Oakley, J ; Ducruet, A
ispartofThe New England journal of medicine, March 12, 2015, Vol.372(11), pp.1019-1030
identifierE-ISSN: 1533-4406 ; DOI: 10.1056/NEJMoa1414905
subjectAged–Diagnostic Imaging ; Aged, 80 and Over–Therapy ; Angiography, Digital Subtraction–Chemically Induced ; Brain Ischemia–Therapeutic Use ; Cerebral Hemorrhage–Mortality ; Combined Modality Therapy–Therapy ; Endovascular Procedures–Instrumentation ; Female–Therapeutic Use ; Fibrinolytic Agents–Therapeutic Use ; Humans–Therapeutic Use ; Intention to Treat Analysis–Therapeutic Use ; Male–Therapeutic Use ; Middle Aged–Therapeutic Use ; Reperfusion–Therapeutic Use ; Single-Blind Method–Therapeutic Use ; Stents–Therapeutic Use ; Stroke–Therapeutic Use ; Thrombectomy–Therapeutic Use ; Tissue Plasminogen Activator–Therapeutic Use ; Tomography, X-Ray Computed–Therapeutic Use ; Abridged ; Fibrinolytic Agents ; Tissue Plasminogen Activator
descriptionBACKGROUNDAmong patients with a proximal vessel occlusion in the anterior circulation, 60 to 80% of patients die within 90 days after stroke onset or do not regain functional independence despite alteplase treatment. We evaluated rapid endovascular treatment in addition to standard care in patients with...
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0Goyal, Mayank
1Demchuk, Andrew M
2Menon, Bijoy K
3Eesa, Muneer
4Rempel, Jeremy L
5Thornton, John
6Roy, Daniel
7Jovin, Tudor G
8Willinsky, Robert A
9Sapkota, Biggya L
10Dowlatshahi, Dar
11Frei, Donald F
12Kamal, Noreen R
13Montanera, Walter J
14Poppe, Alexandre Y
15Ryckborst, Karla J
16Silver, Frank L
17Shuaib, Ashfaq
18Tampieri, Donatella
19Williams, David
20Bang, Oh Young
21Baxter, Blaise W
22Burns, Paul A
23Choe, Hana
24Heo, Ji-Hoe
25Holmstedt, Christine A
26Jankowitz, Brian
27Kelly, Michael
28Linares, Guillermo
29Mandzia, Jennifer L
30Shankar, Jai
31Sohn, Sung-Il
32Swartz, Richard H
33Barber, Philip A
34Coutts, Shelagh B
35Smith, Eric E
36Morrish, William F
37Weill, Alain
38Subramaniam, Suresh
39Mitha, Alim P
40Wong, John H
41Lowerison, Mark W
42Sajobi, Tolulope T
43Hill, Michael D
titleRandomized assessment of rapid endovascular treatment of ischemic stroke.
descriptionBACKGROUNDAmong patients with a proximal vessel occlusion in the anterior circulation, 60 to 80% of patients die within 90 days after stroke onset or do not regain functional independence despite alteplase treatment. We evaluated rapid endovascular treatment in addition to standard care in patients with...
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0Aged–Diagnostic Imaging
1Aged, 80 and Over–Therapy
2Angiography, Digital Subtraction–Chemically Induced
3Brain Ischemia–Therapeutic Use
4Cerebral Hemorrhage–Mortality
5Combined Modality Therapy–Therapy
6Endovascular Procedures–Instrumentation
7Female–Therapeutic Use
8Fibrinolytic Agents–Therapeutic...
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110.1056/NEJMoa1414905
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1Goyal, M
2Demchuk, A M
3Menon, B K
4Eesa, M
5Ryckborst, K J
6Wright, M R
7Kamal, N R
8Andersen, L
9Randhawa, P A
10Stewart, T
11Patil, S
12Minhas, P
13Almekhlafi, M
14Mishra, S
15Clement, F
16Sajobi, T
17Shuaib, A
18Montanera, W J
19Roy, D
20Silver, F L
21Jovin, T G
22Frei, D F
23Sapkota, B
24Rempel, J L
25Thornton, J
26Williams, D
27Tampieri, D
28Poppe, A Y
29Dowlatshahi, D
30Wong, J H
31Mitha, A P
32Subramaniam, S
33Hull, G
34Lowerison, M W
35Salluzzi, M
36Maxwell, M
37Lacusta, S
38Drupals, E
39Armitage, K
40Barber, P A
41Smith, E E
42Morrish, W F
43Coutts, S B
44Derdeyn, C
45Demaerschalk, B
46Yavagil, D
47Martin, R
48Brant, R
49Yu, Y
50Willinsky, R A
51Weill, A
52Kenney, C
53Aram, H
54Stys, P K
55Watson, T W
56Klein, G
57Pearson, D
58Couillard, P
59Trivedi, A
60Singh, D
61Klourfeld, E
62Imoukhuede, O
63Nikneshan, D
64Blayney, S
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82Naik, S S
83Emery, D J
84Owen, R J
85Kotylak, T B
86Ashforth, R A
87Yeo, T A
88Mcnally, D
89Siddiqui, M
90Saqqur, M
91Hussain, D
92Kalashyan, H
93Manosalva, A
94Kate, M
95Gioia, L
96Hasan, S
97Mohammad, A
98Muratoglu, M
99Cullen, A
100...
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citationpf 1019 pt 1030 vol 372 issue 11
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titleRandomized assessment of rapid endovascular treatment of ischemic stroke.
authorGoyal, Mayank ; Demchuk, Andrew M ; Menon, Bijoy K ; Eesa, Muneer ; Rempel, Jeremy L ; Thornton, John ; Roy, Daniel ; Jovin, Tudor G ; Willinsky, Robert A ; Sapkota, Biggya L ; Dowlatshahi, Dar ; Frei, Donald F ; Kamal, Noreen R ; Montanera, Walter J ; Poppe, Alexandre Y ; Ryckborst, Karla J ; Silver,...
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1Aged, 80 and Over–Therapy
2Angiography, Digital Subtraction–Chemically Induced
3Brain Ischemia–Therapeutic Use
4Cerebral Hemorrhage–Mortality
5Combined Modality Therapy–Therapy
6Endovascular Procedures–Instrumentation
7Female–Therapeutic Use
8Fibrinolytic Agents–Therapeutic...
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0Goyal, Mayank
1Demchuk, Andrew M
2Menon, Bijoy K
3Eesa, Muneer
4Rempel, Jeremy L
5Thornton, John
6Roy, Daniel
7Jovin, Tudor G
8Willinsky, Robert A
9Sapkota, Biggya L
10Dowlatshahi, Dar
11Frei, Donald F
12Kamal, Noreen R
13Montanera, Walter J
14Poppe, Alexandre Y
15Ryckborst, Karla J
16Silver, Frank L
17Shuaib, Ashfaq
18Tampieri, Donatella
19Williams, David
20Bang, Oh Young
21Baxter, Blaise W
22Burns, Paul A
23Choe, Hana
24Heo, Ji-Hoe
25Holmstedt, Christine A
26Jankowitz, Brian
27Kelly, Michael
28Linares, Guillermo
29Mandzia, Jennifer L
30Shankar, Jai
31Sohn, Sung-Il
32Swartz, Richard H
33Barber, Philip A
34Coutts, Shelagh B
35Smith, Eric E
36Morrish, William F
37Weill, Alain
38Subramaniam, Suresh
39Mitha, Alim P
40Wong, John H
41Lowerison, Mark W
42Sajobi, Tolulope T
43Hill, Michael D
44Hill, M D
45Goyal, M
46Demchuk, A M
47Menon, B K
48Eesa, M
49Ryckborst, K J
50Wright, M R
51Kamal, N R
52Andersen, L
53Randhawa, P A
54Stewart, T
55Patil, S
56Minhas, P
57Almekhlafi, M
58Mishra, S
59Clement, F
60Sajobi, T
61Shuaib, A
62Montanera, W J
63Roy, D
64Silver, F L
65Jovin, T G
66Frei, D F
67Sapkota, B
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23Choe, Hana
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13Almekhlafi, M
14Mishra, S
15Clement, F
16Sajobi, T
17Shuaib, A
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19Roy, D
20Silver, F L
21Jovin, T G
22Frei, D F
23Sapkota, B
24Rempel, J L
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27Tampieri, D
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30Wong, J H
31Mitha, A P
32Subramaniam, S
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39Armitage, K
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43Coutts, S B
44Derdeyn, C
45Demaerschalk, B
46Yavagil, D
47Martin, R
48Brant, R
49Yu, Y
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51Weill, A
52Kenney, C
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54Stys, P K
55Watson, T W
56Klein, G
57Pearson, D
58Couillard, P
59Trivedi, A
60Singh, D
61Klourfeld, E
62Imoukhuede, O
63Nikneshan, D
64Blayney, S
65Reddy, R
66Choi, P
67Horton, M
68Musuka, T
69Dubuc, V
70Field, T S
71Desai, J
72Adatia, S
73Alseraya, A
74Nambiar, V
75van Dijk, R
76Newcommon, N J
77Schwindt, B
78Butcher, K
79Jeerakathil, T
80Buck, B
81Khan, K
82Naik, S S
83Emery, D J
84Owen, R J
85Kotylak, T B
86Ashforth, R A
87Yeo, T A
88McNally, D
89Siddiqui, M
90Saqqur, M
91Hussain, D
92Kalashyan, H
93Manosalva, A
94Kate, M
95Gioia, L
96Hasan, S
97Mohammad, A
98Muratoglu, M
99Cullen, A
100...
atitleRandomized assessment of rapid endovascular treatment of ischemic stroke.
jtitleThe New England journal of medicine
risdate20150312
volume372
issue11
spage1019
epage1030
pages1019-1030
eissn1533-4406
formatjournal
genrearticle
ristypeJOUR
abstractBACKGROUNDAmong patients with a proximal vessel occlusion in the anterior circulation, 60 to 80% of patients die within 90 days after stroke onset or do not regain functional independence despite alteplase treatment. We evaluated rapid endovascular treatment in addition to standard care in patients with...
doi10.1056/NEJMoa1414905
urlhttp://search.proquest.com/docview/1663657444/
issn00284793
date2015-03-12