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A porcine model of hypertensive cardiomyopathy: implications for heart failure with preserved ejection fraction

Heart failure with preserved ejection fraction (HFPEF) evolves with the accumulation of risk factors. Relevant animal models to identify potential therapeutic targets and to test novel therapies for HFPEF are missing. We induced hypertension and hyperlipidemia in landrace pigs (n = 8) by deoxycortic... Full description

Journal Title: American Journal of Physiology Nov 1, 2015, Vol.309(9), p.H1407
Main Author: Schwarzl, Michael
Other Authors: Hamdani, Nazha , Seiler, Sebastian , Alogna, Alessio , Manninger, Martin , Reilly, Svetlana , Zirngast, Birgit , Kirsch, Alexander , Steendijk, Paul , Verderber, Jochen , Zweiker, David , Eller, Philipp , Höfler, Gerald , Schauer, Silvia , Eller, Kathrin , Maechler, Heinrich , Pieske, Burkert , Linke, Wolfgang , Casadei
Format: Electronic Article Electronic Article
Language: English
Subjects:
ID: ISSN: 03636135 ; E-ISSN: 15221539
Link: http://search.proquest.com/docview/1730772736/?pq-origsite=primo
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title: A porcine model of hypertensive cardiomyopathy: implications for heart failure with preserved ejection fraction
format: Article
creator:
  • Schwarzl, Michael
  • Hamdani, Nazha
  • Seiler, Sebastian
  • Alogna, Alessio
  • Manninger, Martin
  • Reilly, Svetlana
  • Zirngast, Birgit
  • Kirsch, Alexander
  • Steendijk, Paul
  • Verderber, Jochen
  • Zweiker, David
  • Eller, Philipp
  • Höfler, Gerald
  • Schauer, Silvia
  • Eller, Kathrin
  • Maechler, Heinrich
  • Pieske, Burkert
  • Linke, Wolfgang
  • Casadei
subjects:
  • Risk Factors
  • Heart Failure
  • Hogs
  • Phosphorylation
  • Nitric Oxide
ispartof: American Journal of Physiology, Nov 1, 2015, Vol.309(9), p.H1407
description: Heart failure with preserved ejection fraction (HFPEF) evolves with the accumulation of risk factors. Relevant animal models to identify potential therapeutic targets and to test novel therapies for HFPEF are missing. We induced hypertension and hyperlipidemia in landrace pigs (n = 8) by deoxycorticosteroneacetate...
language: eng
source:
identifier: ISSN: 03636135 ; E-ISSN: 15221539
fulltext: fulltext
issn:
  • 03636135
  • 0363-6135
  • 15221539
  • 1522-1539
url: Link


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titleA porcine model of hypertensive cardiomyopathy: implications for heart failure with preserved ejection fraction
creatorSchwarzl, Michael ; Hamdani, Nazha ; Seiler, Sebastian ; Alogna, Alessio ; Manninger, Martin ; Reilly, Svetlana ; Zirngast, Birgit ; Kirsch, Alexander ; Steendijk, Paul ; Verderber, Jochen ; Zweiker, David ; Eller, Philipp ; Höfler, Gerald ; Schauer, Silvia ; Eller, Kathrin ; Maechler, Heinrich ; Pieske, Burkert ; Linke, Wolfgang ; Casadei
ispartofAmerican Journal of Physiology, Nov 1, 2015, Vol.309(9), p.H1407
identifierISSN: 03636135 ; E-ISSN: 15221539
subjectRisk Factors ; Heart Failure ; Hogs ; Phosphorylation ; Nitric Oxide
descriptionHeart failure with preserved ejection fraction (HFPEF) evolves with the accumulation of risk factors. Relevant animal models to identify potential therapeutic targets and to test novel therapies for HFPEF are missing. We induced hypertension and hyperlipidemia in landrace pigs (n = 8) by deoxycorticosteroneacetate...
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titleA porcine model of hypertensive cardiomyopathy: implications for heart failure with preserved ejection fraction
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citationpf H1407 vol 309 issue 9
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titleA porcine model of hypertensive cardiomyopathy: implications for heart failure with preserved ejection fraction
authorSchwarzl, Michael ; Hamdani, Nazha ; Seiler, Sebastian ; Alogna, Alessio ; Manninger, Martin ; Reilly, Svetlana ; Zirngast, Birgit ; Kirsch, Alexander ; Steendijk, Paul ; Verderber, Jochen ; Zweiker, David ; Eller, Philipp ; Höfler, Gerald ; Schauer, Silvia ; Eller, Kathrin ; Maechler, Heinrich ; Pieske,...
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13Schauer, Silvia
14Eller, Kathrin
15Maechler, Heinrich
16Pieske, Burkert
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atitleA porcine model of hypertensive cardiomyopathy: implications for heart failure with preserved ejection fraction
jtitleAmerican Journal of Physiology
risdate20151101
volume309
issue9
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abstractHeart failure with preserved ejection fraction (HFPEF) evolves with the accumulation of risk factors. Relevant animal models to identify potential therapeutic targets and to test novel therapies for HFPEF are missing. We induced hypertension and hyperlipidemia in landrace pigs (n = 8) by deoxycorticosteroneacetate...
copBethesda
pubAmerican Physiological Society
urlhttp://search.proquest.com/docview/1730772736/
doi10.1152/ajpheart.00542.2015
pagesH1407-18
date2015-11-01