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Gsa deficiency in adipose tissue improves glucose metabolism and insulin sensitivity without an effect on body weight

Gsa, the G protein that transduces receptor-stimulated cAMP generation, mediates sympathetic nervous system stimulation of brown adipose tissue (BAT) thermogenesis and browning of white adipose tissue (WAT), which are both potential targets for treating obesity, as well as lipolysis. We generated a... Full description

Journal Title: Proceedings of the National Academy of Sciences of the United States of America Jan 12, 2016, Vol.113(2), p.446
Main Author: Li, Yong-Qi
Other Authors: Shrestha, Yogendra , Chen, Min , Chanturiya, Tatyana , Gavrilova, Oksana , Weinstein, Lee
Format: Electronic Article Electronic Article
Language: English
Subjects:
Quelle: © ProQuest LLC All rights reserved
ID: ISSN: 00278424 ; E-ISSN: 10916490
Link: http://search.proquest.com/docview/1759028512/?pq-origsite=primo
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recordid: proquest1759028512
title: Gsa deficiency in adipose tissue improves glucose metabolism and insulin sensitivity without an effect on body weight
format: Article
creator:
  • Li, Yong-Qi
  • Shrestha, Yogendra
  • Chen, Min
  • Chanturiya, Tatyana
  • Gavrilova, Oksana
  • Weinstein, Lee
subjects:
  • Proteins
  • Thermogenesis
  • Metabolism
  • Adipocytes
  • Glucose
  • Lipids
ispartof: Proceedings of the National Academy of Sciences of the United States of America, Jan 12, 2016, Vol.113(2), p.446
description: Gsa, the G protein that transduces receptor-stimulated cAMP generation, mediates sympathetic nervous system stimulation of brown adipose tissue (BAT) thermogenesis and browning of white adipose tissue (WAT), which are both potential targets for treating obesity, as well as lipolysis. We generated a mouse...
language: eng
source: © ProQuest LLC All rights reserved
identifier: ISSN: 00278424 ; E-ISSN: 10916490
fulltext: fulltext
issn:
  • 00278424
  • 0027-8424
  • 10916490
  • 1091-6490
url: Link


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titleGsa deficiency in adipose tissue improves glucose metabolism and insulin sensitivity without an effect on body weight
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identifierISSN: 00278424 ; E-ISSN: 10916490
subjectProteins ; Thermogenesis ; Metabolism ; Adipocytes ; Glucose ; Lipids
descriptionGsa, the G protein that transduces receptor-stimulated cAMP generation, mediates sympathetic nervous system stimulation of brown adipose tissue (BAT) thermogenesis and browning of white adipose tissue (WAT), which are both potential targets for treating obesity, as well as lipolysis. We generated a mouse...
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citationpf 446 vol 113 issue 2
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titleGsa deficiency in adipose tissue improves glucose metabolism and insulin sensitivity without an effect on body weight
authorLi, Yong-Qi ; Shrestha, Yogendra ; Chen, Min ; Chanturiya, Tatyana ; Gavrilova, Oksana ; Weinstein, Lee
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abstractGsa, the G protein that transduces receptor-stimulated cAMP generation, mediates sympathetic nervous system stimulation of brown adipose tissue (BAT) thermogenesis and browning of white adipose tissue (WAT), which are both potential targets for treating obesity, as well as lipolysis. We generated a mouse...
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date2016-01-12