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Does posterior cingulate hypometabolism result from disconnection or local pathology across preclinical and clinical stages of Alzheimer's disease?

PURPOSEPosterior cingulate cortex (PCC) hypometabolism as measured by FDG PET is an indicator of Alzheimer's disease (AD) in prodromal stages, such as in mild cognitive impairment (MCI), and has been found to be closely associated with hippocampus atrophy in AD dementia. We studied the effects of lo... Full description

Journal Title: European journal of nuclear medicine and molecular imaging March 2016, Vol.43(3), pp.526-536
Main Author: Teipel, Stefan
Other Authors: Grothe, Michel J , Teipel, Stefan
Format: Electronic Article Electronic Article
Language: English
Subjects:
ID: E-ISSN: 1619-7089 ; DOI: 10.1007/s00259-015-3222-3
Link: http://search.proquest.com/docview/1761470388/?pq-origsite=primo
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title: Does posterior cingulate hypometabolism result from disconnection or local pathology across preclinical and clinical stages of Alzheimer's disease?
format: Article
creator:
  • Teipel, Stefan
  • Grothe, Michel J
  • Teipel, Stefan
subjects:
  • Aged–Diagnostic Imaging
  • Aging–Metabolism
  • Alzheimer Disease–Physiopathology
  • Atrophy–Diagnostic Imaging
  • Cognition–Metabolism
  • Cognitive Dysfunction–Physiopathology
  • Female–Chemistry
  • Fluorodeoxyglucose F18–Diagnostic Imaging
  • Gray Matter–Pathology
  • Gyrus Cinguli–Metabolism
  • Hippocampus–Physiopathology
  • Humans–Diagnostic Imaging
  • Image Processing, Computer-Assisted–Pathology
  • Magnetic Resonance Imaging–Pathology
  • Male–Pathology
  • Middle Aged–Pathology
  • Positron-Emission Tomography–Pathology
  • Fluorodeoxyglucose F18
  • Amyloid Pathology
  • Disconnection
  • Early Diagnosis
  • Hippocampus Atrophy
  • Multimodal Imaging
  • Prodromal Alzheimer’s Disease
ispartof: European journal of nuclear medicine and molecular imaging, March 2016, Vol.43(3), pp.526-536
description: PURPOSEPosterior cingulate cortex (PCC) hypometabolism as measured by FDG PET is an indicator of Alzheimer's disease (AD) in prodromal stages, such as in mild cognitive impairment (MCI), and has been found to be closely associated with hippocampus atrophy in AD dementia. We studied the effects of local...
language: eng
source:
identifier: E-ISSN: 1619-7089 ; DOI: 10.1007/s00259-015-3222-3
fulltext: fulltext
issn:
  • 16197089
  • 1619-7089
url: Link


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titleDoes posterior cingulate hypometabolism result from disconnection or local pathology across preclinical and clinical stages of Alzheimer's disease?
creatorTeipel, Stefan ; Grothe, Michel J ; Teipel, Stefan
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ispartofEuropean journal of nuclear medicine and molecular imaging, March 2016, Vol.43(3), pp.526-536
identifierE-ISSN: 1619-7089 ; DOI: 10.1007/s00259-015-3222-3
subjectAged–Diagnostic Imaging ; Aging–Metabolism ; Alzheimer Disease–Physiopathology ; Atrophy–Diagnostic Imaging ; Cognition–Metabolism ; Cognitive Dysfunction–Physiopathology ; Female–Chemistry ; Fluorodeoxyglucose F18–Diagnostic Imaging ; Gray Matter–Pathology ; Gyrus Cinguli–Metabolism ; Hippocampus–Physiopathology ; Humans–Diagnostic Imaging ; Image Processing, Computer-Assisted–Pathology ; Magnetic Resonance Imaging–Pathology ; Male–Pathology ; Middle Aged–Pathology ; Positron-Emission Tomography–Pathology ; Fluorodeoxyglucose F18 ; Amyloid Pathology ; Disconnection ; Early Diagnosis ; Hippocampus Atrophy ; Multimodal Imaging ; Prodromal Alzheimer’s Disease
descriptionPURPOSEPosterior cingulate cortex (PCC) hypometabolism as measured by FDG PET is an indicator of Alzheimer's disease (AD) in prodromal stages, such as in mild cognitive impairment (MCI), and has been found to be closely associated with hippocampus atrophy in AD dementia. We studied the effects of local...
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titleDoes posterior cingulate hypometabolism result from disconnection or local pathology across preclinical and clinical stages of Alzheimer's disease?
descriptionPURPOSEPosterior cingulate cortex (PCC) hypometabolism as measured by FDG PET is an indicator of Alzheimer's disease (AD) in prodromal stages, such as in mild cognitive impairment (MCI), and has been found to be closely associated with hippocampus atrophy in AD dementia. We studied the effects of local...
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4Jack, Clifford R
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7Toga, Arthur W
8Beckett, Laurel
9Green, Robert C
10Saykin, Andrew J
11Morris, John
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14Sorensen, Greg
15Carrillo, Maria
16Kuller, Lew
17Raichle, Marc
18Paul, Steven
19Davies, Peter
20Fillit, Howard
21Hefti, Franz
22Holtzman, David
23Mesulam, M Marcel
24Potter, William
25Snyder, Peter
26Schwartz, Adam
27Montine, Tom
28Thomas, Ronald G
29Donohue, Michael
30Walter, Sarah
31Gessert, Devon
32Sather, Tamie
33Jiminez, Gus
34Balasubramanian, Archana B
35Mason, Jennifer
36Sim, Iris
37Harvey, Danielle
38Bernstein, Matthew
39Fox, Nick
40Thompson, Paul
41Schuff, Norbert
42Decarli, Charles
43Borowski, Bret
44Gunter, Jeff
45Senjem, Matt
46Vemuri, Prashanthi
47Jones, David
48Kantarci, Kejal
49Ward, Chad
50Koeppe, Robert A
51Foster, Norm
52Reiman, Eric M
53Chen, Kewei
54Mathis, Chet
55Landau, Susan
56Morris, John C
57Cairns, Nigel J
58Franklin, Erin
59Taylor-Reinwald, Lisa
60Lee, Virginia
61Korecka, Magdalena
62Figurski, Michal
63Crawford, Karen
64Neu, Scott
65Foroud, Tatiana M
66Potkin, Steven
67Shen, Li
68Faber, Kelley
69Kim, Sungeun
70Nho, Kwangsik
71Thal, Lean
72Thal, Leon
73Buckholtz, Neil
74Snyder, Peter J
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76Frank, Richard
77Hsiao, John
78Kaye, Jeffrey
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93Lord, Joanne L
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95Albers, Colleen S
96Knopman, David
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titleDoes posterior cingulate hypometabolism result from disconnection or local pathology across preclinical and clinical stages of Alzheimer's disease?
authorTeipel, Stefan ; Grothe, Michel J ; Teipel, Stefan
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6Female–Chemistry
7Fluorodeoxyglucose F18–Diagnostic Imaging
8Gray Matter–Pathology
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9Toga, Arthur W
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11Green, Robert C
12Saykin, Andrew J
13Morris, John
14Shaw, Leslie M
15Khachaturian, Zaven
16Sorensen, Greg
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19Raichle, Marc
20Paul, Steven
21Davies, Peter
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26Potter, William
27Snyder, Peter
28Schwartz, Adam
29Montine, Tom
30Thomas, Ronald G
31Donohue, Michael
32Walter, Sarah
33Gessert, Devon
34Sather, Tamie
35Jiminez, Gus
36Balasubramanian, Archana B
37Mason, Jennifer
38Sim, Iris
39Harvey, Danielle
40Bernstein, Matthew
41Fox, Nick
42Thompson, Paul
43Schuff, Norbert
44Decarli, Charles
45Borowski, Bret
46Gunter, Jeff
47Senjem, Matt
48Vemuri, Prashanthi
49Jones, David
50Kantarci, Kejal
51Ward, Chad
52Koeppe, Robert A
53Foster, Norm
54Reiman, Eric M
55Chen, Kewei
56Mathis, Chet
57Landau, Susan
58Morris, John C
59Cairns, Nigel J
60Franklin, Erin
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62Lee, Virginia
63Korecka, Magdalena
64Figurski, Michal
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66Neu, Scott
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78Frank, Richard
79Hsiao, John
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68Faber, Kelley
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79Quinn, Joseph
80Silbert, Lisa
81Lind, Betty
82Carter, Raina
83Dolen, Sara
84Schneider, Lon S
85Pawluczyk, Sonia
86Becerra, Mauricio
87Teodoro, Liberty
88Spann, Bryan M
89Brewer, James
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atitleDoes posterior cingulate hypometabolism result from disconnection or local pathology across preclinical and clinical stages of Alzheimer's disease?
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abstractPURPOSEPosterior cingulate cortex (PCC) hypometabolism as measured by FDG PET is an indicator of Alzheimer's disease (AD) in prodromal stages, such as in mild cognitive impairment (MCI), and has been found to be closely associated with hippocampus atrophy in AD dementia. We studied the effects of local...
doi10.1007/s00259-015-3222-3
urlhttp://search.proquest.com/docview/1761470388/
issn16197070
date2016-03-01