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Alcohol consumption and cardiovascular disease, cancer, injury, admission to hospital, and mortality: a prospective cohort study.

BACKGROUNDAlcohol consumption is proposed to be the third most important modifiable risk factor for death and disability. However, alcohol consumption has been associated with both benefits and harms, and previous studies were mostly done in high-income countries. We investigated associations betwee... Full description

Journal Title: Lancet (London England), November 14, 2015, Vol.386(10007), pp.1945-1954
Main Author: Smyth, Andrew
Other Authors: Teo, Koon K , Rangarajan, Sumathy , O'Donnell, Martin , Zhang, Xiaohe , Rana, Punam , Leong, Darryl P , Dagenais, Gilles , Seron, Pamela , Rosengren, Annika , Schutte, Aletta E , Lopez-Jaramillo, Patricio , Oguz, Ayetkin , Chifamba, Jephat , Diaz, Rafael , Lear, Scott , Avezum, Alvaro , Kumar, Rajesh , Mohan
Format: Electronic Article Electronic Article
Language: English
Subjects:
ID: E-ISSN: 1474-547X ; DOI: 10.1016/S0140-6736(15)00235-4
Link: http://search.proquest.com/docview/1762961960/?pq-origsite=primo
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title: Alcohol consumption and cardiovascular disease, cancer, injury, admission to hospital, and mortality: a prospective cohort study.
format: Article
creator:
  • Smyth, Andrew
  • Teo, Koon K
  • Rangarajan, Sumathy
  • O'Donnell, Martin
  • Zhang, Xiaohe
  • Rana, Punam
  • Leong, Darryl P
  • Dagenais, Gilles
  • Seron, Pamela
  • Rosengren, Annika
  • Schutte, Aletta E
  • Lopez-Jaramillo, Patricio
  • Oguz, Ayetkin
  • Chifamba, Jephat
  • Diaz, Rafael
  • Lear, Scott
  • Avezum, Alvaro
  • Kumar, Rajesh
  • Mohan
subjects:
  • Adult–Epidemiology
  • Aged–Epidemiology
  • Alcohol Drinking–Statistics & Numerical Data
  • Cardiovascular Diseases–Epidemiology
  • Cohort Studies–Epidemiology
  • Developed Countries–Epidemiology
  • Developing Countries–Epidemiology
  • Female–Epidemiology
  • Hospitalization–Epidemiology
  • Humans–Epidemiology
  • Male–Epidemiology
  • Middle Aged–Epidemiology
  • Neoplasms–Epidemiology
  • Proportional Hazards Models–Epidemiology
  • Wounds and Injuries–Epidemiology
  • Abridged
ispartof: Lancet (London, England), November 14, 2015, Vol.386(10007), pp.1945-1954
description: BACKGROUNDAlcohol consumption is proposed to be the third most important modifiable risk factor for death and disability. However, alcohol consumption has been associated with both benefits and harms, and previous studies were mostly done in high-income countries. We investigated associations between alcohol consumption and outcomes in a prospective cohort of countries at different economic levels in five continents. METHODSWe included information from 12 countries participating in the Prospective Urban Rural Epidemiological (PURE) study, a prospective cohort study of individuals aged 35-70 years. We used Cox proportional hazards regression to study associations with mortality (n=2723), cardiovascular disease (n=2742), myocardial infarction (n=979), stroke (n=817), alcohol-related cancer (n=764), injury (n=824), admission to hospital (n=8786), and for a composite of these outcomes (n=11,963). FINDINGSWe included 114,970 adults, of whom 12,904 (11%) were from high-income countries (HICs),...
language: eng
source:
identifier: E-ISSN: 1474-547X ; DOI: 10.1016/S0140-6736(15)00235-4
fulltext: fulltext
issn:
  • 1474547X
  • 1474-547X
url: Link


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titleAlcohol consumption and cardiovascular disease, cancer, injury, admission to hospital, and mortality: a prospective cohort study.
creatorSmyth, Andrew ; Teo, Koon K ; Rangarajan, Sumathy ; O'Donnell, Martin ; Zhang, Xiaohe ; Rana, Punam ; Leong, Darryl P ; Dagenais, Gilles ; Seron, Pamela ; Rosengren, Annika ; Schutte, Aletta E ; Lopez-Jaramillo, Patricio ; Oguz, Ayetkin ; Chifamba, Jephat ; Diaz, Rafael ; Lear, Scott ; Avezum, Alvaro ; Kumar, Rajesh ; Mohan
contributorYusuf, S (correspondence author) ; Rangarajan, S (record owner) ; Teo, K K ; Chow, C K ; O'Donnell, M ; Mente, A ; Leong, D ; Smyth, A ; Joseph, P ; Islam, S ; Zhang, M ; Hu, W ; Ramasundarahettige, C ; Wong, G ; Dayal, L ; Casanova, A ; Dehghan, M ; Lewis, G ; Dejesus
ispartofLancet (London, England), November 14, 2015, Vol.386(10007), pp.1945-1954
identifierE-ISSN: 1474-547X ; DOI: 10.1016/S0140-6736(15)00235-4
subjectAdult–Epidemiology ; Aged–Epidemiology ; Alcohol Drinking–Statistics & Numerical Data ; Cardiovascular Diseases–Epidemiology ; Cohort Studies–Epidemiology ; Developed Countries–Epidemiology ; Developing Countries–Epidemiology ; Female–Epidemiology ; Hospitalization–Epidemiology ; Humans–Epidemiology ; Male–Epidemiology ; Middle Aged–Epidemiology ; Neoplasms–Epidemiology ; Proportional Hazards Models–Epidemiology ; Wounds and Injuries–Epidemiology ; Abridged
descriptionBACKGROUNDAlcohol consumption is proposed to be the third most important modifiable risk factor for death and disability. However, alcohol consumption has been associated with both benefits and harms, and previous studies were mostly done in high-income countries. We investigated associations between alcohol consumption and outcomes in a prospective cohort of countries at different economic levels in five continents. METHODSWe included information from 12 countries participating in the Prospective Urban Rural Epidemiological (PURE) study, a prospective cohort study of individuals aged 35-70 years. We used Cox proportional hazards regression to study associations with mortality (n=2723), cardiovascular disease (n=2742), myocardial infarction (n=979), stroke (n=817), alcohol-related cancer (n=764), injury (n=824), admission to hospital (n=8786), and for a composite of these outcomes (n=11,963). FINDINGSWe included 114,970 adults, of whom 12,904 (11%) were from high-income countries (HICs),...
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titleAlcohol consumption and cardiovascular disease, cancer, injury, admission to hospital, and mortality: a prospective cohort study.
descriptionBACKGROUNDAlcohol consumption is proposed to be the third most important modifiable risk factor for death and disability. However, alcohol consumption has been associated with both benefits and harms, and previous studies were mostly done in high-income countries. We investigated associations between alcohol consumption and outcomes in a prospective cohort of countries at different economic levels in five continents. METHODSWe included information from 12 countries participating in the Prospective Urban Rural Epidemiological (PURE) study, a prospective cohort study of individuals aged 35-70 years. We used Cox proportional hazards regression to study associations with mortality (n=2723), cardiovascular disease (n=2742), myocardial infarction (n=979), stroke (n=817), alcohol-related cancer (n=764), injury (n=824), admission to hospital (n=8786), and for a composite of these outcomes (n=11,963). FINDINGSWe included 114,970 adults, of whom 12,904 (11%) were from high-income countries (HICs),...
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20Chin, S L
21Hari, D
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23Kay, I
24Agapay, D
25Solano, R
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28Rimac, J
29Trottier, S
30Elsheikh, W
31Mustaha, M
32Tongana, T
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35Ramezani, E
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38Mcqueen, M
39Hall, K
40Keys, J
41Wang, X
42Keneth, J
43Devanath, A
44Diaz, R
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50Rahman, O
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53Rabbani, K A
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55Mannan, A
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citationpf 1945 pt 1954 vol 386 issue 10007
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titleAlcohol consumption and cardiovascular disease, cancer, injury, admission to hospital, and mortality: a prospective cohort study.
authorSmyth, Andrew ; Teo, Koon K ; Rangarajan, Sumathy ; O'Donnell, Martin ; Zhang, Xiaohe ; Rana, Punam ; Leong, Darryl P ; Dagenais, Gilles ; Seron, Pamela ; Rosengren, Annika ; Schutte, Aletta E ; Lopez-Jaramillo, Patricio ; Oguz, Ayetkin ; Chifamba, Jephat ; Diaz, Rafael ; Lear, Scott ; Avezum, Alvaro ; Kumar, Rajesh ; Mohan
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5Developed Countries–Epidemiology
6Developing Countries–Epidemiology
7Female–Epidemiology
8Hospitalization–Epidemiology
9Humans–Epidemiology
10Male–Epidemiology
11Middle Aged–Epidemiology
12Neoplasms–Epidemiology
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21Yang, Wang
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24Yusuf, Salim
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39Dayal, L
40Casanova, A
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43Dejesus, J
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46Hari, D
47Farago, L
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55Elsheikh, W
56Mustaha, M
57Tongana, T
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60Sintaha, M
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74Turbide, G
75Auger, D
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77Proulx, M C
78Cayer, M
79Bonneville, N
80Lear, S
81Gasevic, D
82Corber, E
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85Wielgosz, A
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atitleAlcohol consumption and cardiovascular disease, cancer, injury, admission to hospital, and mortality: a prospective cohort study.
jtitleLancet (London, England)
risdate20151114
volume386
issue10007
spage1945
epage1954
pages1945-1954
eissn1474-547X
formatjournal
genrearticle
ristypeJOUR
abstractBACKGROUNDAlcohol consumption is proposed to be the third most important modifiable risk factor for death and disability. However, alcohol consumption has been associated with both benefits and harms, and previous studies were mostly done in high-income countries. We investigated associations between alcohol consumption and outcomes in a prospective cohort of countries at different economic levels in five continents. METHODSWe included information from 12 countries participating in the Prospective Urban Rural Epidemiological (PURE) study, a prospective cohort study of individuals aged 35-70 years. We used Cox proportional hazards regression to study associations with mortality (n=2723), cardiovascular disease (n=2742), myocardial infarction (n=979), stroke (n=817), alcohol-related cancer (n=764), injury (n=824), admission to hospital (n=8786), and for a composite of these outcomes (n=11,963). FINDINGSWe included 114,970 adults, of whom 12,904 (11%) were from high-income countries (HICs),...
doi10.1016/S0140-6736(15)00235-4
urlhttp://search.proquest.com/docview/1762961960/
issn01406736
date2015-11-14