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Clinical Assessment of Lamina Cribrosa Curvature in Eyes with Primary Open-Angle Glaucoma.

PURPOSEQuantitative evaluation of lamina cribrosa (LC) posterior bowing in primary open-angle glaucoma (POAG) eyes using swept-source optical coherence tomography. METHODSPatients with POAG (n = 123 eyes) and healthy individuals of a similar age (n = 92 eyes) were prospectively recruited. Anterior l... Full description

Journal Title: PloS one 2016, Vol.11(3), p.e0150260
Main Author: Kim, Yong Woo
Other Authors: Jeoung, Jin Wook , Kim, Dai Woo , Girard, Michael J A , Mari, Jean Martial , Park, Ki Ho , Kim, Dong Myung
Format: Electronic Article Electronic Article
Language: English
Subjects:
ID: E-ISSN: 1932-6203 ; DOI: 10.1371/journal.pone.0150260
Link: http://search.proquest.com/docview/1772834491/?pq-origsite=primo
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title: Clinical Assessment of Lamina Cribrosa Curvature in Eyes with Primary Open-Angle Glaucoma.
format: Article
creator:
  • Kim, Yong Woo
  • Jeoung, Jin Wook
  • Kim, Dai Woo
  • Girard, Michael J A
  • Mari, Jean Martial
  • Park, Ki Ho
  • Kim, Dong Myung
subjects:
  • Aged–Pathology
  • Female–Pathology
  • Glaucoma–Pathology
  • Humans–Pathology
  • Male–Pathology
  • Middle Aged–Pathology
  • Retinal Neurons–Pathology
ispartof: PloS one, 2016, Vol.11(3), p.e0150260
description: PURPOSEQuantitative evaluation of lamina cribrosa (LC) posterior bowing in primary open-angle glaucoma (POAG) eyes using swept-source optical coherence tomography. METHODSPatients with POAG (n = 123 eyes) and healthy individuals of a similar age (n = 92 eyes) were prospectively recruited. Anterior laminar insertion depth (ALID) was defined as the vertical distance between the anterior laminar insertion and a reference plane connecting the Bruch's membrane openings (BMO). The mean LC depth (mLCD) was approximated by dividing the area enclosed by the anterior LC, the BMO reference plane, and the two vertical lines for ALID measurement by the length between those two vertical lines. The LC curvature index was defined as the difference between the mLCD and the ALID. The factors influencing the LC curvature index were evaluated. RESULTSThe ALID and mLCD were significantly larger in POAG eyes than in healthy controls (P < 0.05). The LC curvature index was significantly larger in POAG eyes than...
language: eng
source:
identifier: E-ISSN: 1932-6203 ; DOI: 10.1371/journal.pone.0150260
fulltext: fulltext
issn:
  • 19326203
  • 1932-6203
url: Link


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titleClinical Assessment of Lamina Cribrosa Curvature in Eyes with Primary Open-Angle Glaucoma.
creatorKim, Yong Woo ; Jeoung, Jin Wook ; Kim, Dai Woo ; Girard, Michael J A ; Mari, Jean Martial ; Park, Ki Ho ; Kim, Dong Myung
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identifierE-ISSN: 1932-6203 ; DOI: 10.1371/journal.pone.0150260
subjectAged–Pathology ; Female–Pathology ; Glaucoma–Pathology ; Humans–Pathology ; Male–Pathology ; Middle Aged–Pathology ; Retinal Neurons–Pathology
descriptionPURPOSEQuantitative evaluation of lamina cribrosa (LC) posterior bowing in primary open-angle glaucoma (POAG) eyes using swept-source optical coherence tomography. METHODSPatients with POAG (n = 123 eyes) and healthy individuals of a similar age (n = 92 eyes) were prospectively recruited. Anterior laminar insertion depth (ALID) was defined as the vertical distance between the anterior laminar insertion and a reference plane connecting the Bruch's membrane openings (BMO). The mean LC depth (mLCD) was approximated by dividing the area enclosed by the anterior LC, the BMO reference plane, and the two vertical lines for ALID measurement by the length between those two vertical lines. The LC curvature index was defined as the difference between the mLCD and the ALID. The factors influencing the LC curvature index were evaluated. RESULTSThe ALID and mLCD were significantly larger in POAG eyes than in healthy controls (P < 0.05). The LC curvature index was significantly larger in POAG eyes than...
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titleClinical Assessment of Lamina Cribrosa Curvature in Eyes with Primary Open-Angle Glaucoma.
descriptionPURPOSEQuantitative evaluation of lamina cribrosa (LC) posterior bowing in primary open-angle glaucoma (POAG) eyes using swept-source optical coherence tomography. METHODSPatients with POAG (n = 123 eyes) and healthy individuals of a similar age (n = 92 eyes) were prospectively recruited. Anterior laminar insertion depth (ALID) was defined as the vertical distance between the anterior laminar insertion and a reference plane connecting the Bruch's membrane openings (BMO). The mean LC depth (mLCD) was approximated by dividing the area enclosed by the anterior LC, the BMO reference plane, and the two vertical lines for ALID measurement by the length between those two vertical lines. The LC curvature index was defined as the difference between the mLCD and the ALID. The factors influencing the LC curvature index were evaluated. RESULTSThe ALID and mLCD were significantly larger in POAG eyes than in healthy controls (P < 0.05). The LC curvature index was significantly larger in POAG eyes than...
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abstractPURPOSEQuantitative evaluation of lamina cribrosa (LC) posterior bowing in primary open-angle glaucoma (POAG) eyes using swept-source optical coherence tomography. METHODSPatients with POAG (n = 123 eyes) and healthy individuals of a similar age (n = 92 eyes) were prospectively recruited. Anterior laminar insertion depth (ALID) was defined as the vertical distance between the anterior laminar insertion and a reference plane connecting the Bruch's membrane openings (BMO). The mean LC depth (mLCD) was approximated by dividing the area enclosed by the anterior LC, the BMO reference plane, and the two vertical lines for ALID measurement by the length between those two vertical lines. The LC curvature index was defined as the difference between the mLCD and the ALID. The factors influencing the LC curvature index were evaluated. RESULTSThe ALID and mLCD were significantly larger in POAG eyes than in healthy controls (P < 0.05). The LC curvature index was significantly larger in POAG eyes than...
doi10.1371/journal.pone.0150260
urlhttp://search.proquest.com/docview/1772834491/
date2016-01-01