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Individual and Population Level Impact of Key HIV Risk Factors on HIV Incidence Rates in Durban, South Africa.

We aimed to estimate the individual and joint impact of age, marital status and diagnosis with sexually transmitted infections (STIs) on HIV acquisition among young women at a population level in Durban, KwaZulu-Natal, South Africa. A total of 3,978 HIV seronegative women were recruited for four bio... Full description

Journal Title: PloS one 2016, Vol.11(4), p.e0153969
Main Author: Ramjee, Gita
Other Authors: Moonsamy, Suri , Abbai, Nathlee Samantha , Wand, Handan
Format: Electronic Article Electronic Article
Language: English
Subjects:
ID: E-ISSN: 1932-6203 ; DOI: 10.1371/journal.pone.0153969
Link: http://search.proquest.com/docview/1784463206/?pq-origsite=primo
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recordid: proquest1784463206
title: Individual and Population Level Impact of Key HIV Risk Factors on HIV Incidence Rates in Durban, South Africa.
format: Article
creator:
  • Ramjee, Gita
  • Moonsamy, Suri
  • Abbai, Nathlee Samantha
  • Wand, Handan
subjects:
  • Adult–Epidemiology
  • Female–Epidemiology
  • HIV Infections–Epidemiology
  • Humans–Epidemiology
  • Incidence–Epidemiology
  • Risk Factors–Epidemiology
  • South Africa–Epidemiology
ispartof: PloS one, 2016, Vol.11(4), p.e0153969
description: We aimed to estimate the individual and joint impact of age, marital status and diagnosis with sexually transmitted infections (STIs) on HIV acquisition among young women at a population level in Durban, KwaZulu-Natal, South Africa. A total of 3,978 HIV seronegative women were recruited for four biomedical intervention trials from 2002–2009. Point and interval estimates of partial population attributable risk (PAR) were used to quantify the proportion of HIV seroconversions which can be prevented if a combination of risk factors is eliminated from a target population. More than 70% of the observed HIV acquisitions were collectively attributed to the three risk factors: younger age (
language: eng
source:
identifier: E-ISSN: 1932-6203 ; DOI: 10.1371/journal.pone.0153969
fulltext: fulltext
issn:
  • 19326203
  • 1932-6203
url: Link


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titleIndividual and Population Level Impact of Key HIV Risk Factors on HIV Incidence Rates in Durban, South Africa.
creatorRamjee, Gita ; Moonsamy, Suri ; Abbai, Nathlee Samantha ; Wand, Handan
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identifierE-ISSN: 1932-6203 ; DOI: 10.1371/journal.pone.0153969
subjectAdult–Epidemiology ; Female–Epidemiology ; HIV Infections–Epidemiology ; Humans–Epidemiology ; Incidence–Epidemiology ; Risk Factors–Epidemiology ; South Africa–Epidemiology
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descriptionWe aimed to estimate the individual and joint impact of age, marital status and diagnosis with sexually transmitted infections (STIs) on HIV acquisition among young women at a population level in Durban, KwaZulu-Natal, South Africa. A total of 3,978 HIV seronegative women were recruited for four biomedical intervention trials from 2002–2009. Point and interval estimates of partial population attributable risk (PAR) were used to quantify the proportion of HIV seroconversions which can be prevented if a combination of risk factors is eliminated from a target population. More than 70% of the observed HIV acquisitions were collectively attributed to the three risk factors: younger age (<25 years old), unmarried and not cohabiting with a stable/regular partner and diagnosis with STIs. Addressing these risks requires targeted structural, behavioural, biomedical and cultural interventions in order to impact on unacceptably high HIV incidence rates among young women and the population as a whole.
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