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Reduction of intraarticular adhesion of knee by local application of rapamycin in rabbits via inhibition of fibroblast proliferation and collagen synthesis

Background The formation of intraarticular adhesion is a common complication after total knee arthroplasty or anterior cruciate ligament reconstruction. Previously, little research was reported regarding whether the local application of rapamycin (RAPA) could reduce intraarticular adhesion following... Full description

Journal Title: Journal of Orthopaedic Surgery and Research 2016, Vol.11
Main Author: Zhao, Shuai
Other Authors: Sun, Yu , Li, Xiaolei , Wang, Jingcheng , Yan, Lianqi , Chen, Hui , Wang, Daxin , Dai, Jihang , He, Jun , Zhao, Shuai , Sun, Yu , Li, Xiaolei , Wang, Jingcheng , Yan, Lianqi , Chen, Hui , Wang, Daxin , Dai, Jihang , He, Jun
Format: Electronic Article Electronic Article
Language: English
Subjects:
ID: E-ISSN: 1749-799X ; DOI: 10.1186/s13018-016-0375-0
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title: Reduction of intraarticular adhesion of knee by local application of rapamycin in rabbits via inhibition of fibroblast proliferation and collagen synthesis
format: Article
creator:
  • Zhao, Shuai
  • Sun, Yu
  • Li, Xiaolei
  • Wang, Jingcheng
  • Yan, Lianqi
  • Chen, Hui
  • Wang, Daxin
  • Dai, Jihang
  • He, Jun
  • Zhao, Shuai
  • Sun, Yu
  • Li, Xiaolei
  • Wang, Jingcheng
  • Yan, Lianqi
  • Chen, Hui
  • Wang, Daxin
  • Dai, Jihang
  • He, Jun
subjects:
  • Rapamycin
  • Intraarticular Adhesion
  • Fibroblast
  • Collagen Synthesis
ispartof: Journal of Orthopaedic Surgery and Research, 2016, Vol.11
description: Background The formation of intraarticular adhesion is a common complication after total knee arthroplasty or anterior cruciate ligament reconstruction. Previously, little research was reported regarding whether the local application of rapamycin (RAPA) could reduce intraarticular adhesion following...
language: eng
source:
identifier: E-ISSN: 1749-799X ; DOI: 10.1186/s13018-016-0375-0
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issn:
  • 1749799X
  • 1749-799X
url: Link


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titleReduction of intraarticular adhesion of knee by local application of rapamycin in rabbits via inhibition of fibroblast proliferation and collagen synthesis
creatorZhao, Shuai ; Sun, Yu ; Li, Xiaolei ; Wang, Jingcheng ; Yan, Lianqi ; Chen, Hui ; Wang, Daxin ; Dai, Jihang ; He, Jun ; Zhao, Shuai ; Sun, Yu ; Li, Xiaolei ; Wang, Jingcheng ; Yan, Lianqi ; Chen, Hui ; Wang, Daxin ; Dai, Jihang ; He, Jun
ispartofJournal of Orthopaedic Surgery and Research, 2016, Vol.11
identifierE-ISSN: 1749-799X ; DOI: 10.1186/s13018-016-0375-0
subjectRapamycin ; Intraarticular Adhesion ; Fibroblast ; Collagen Synthesis
descriptionBackground The formation of intraarticular adhesion is a common complication after total knee arthroplasty or anterior cruciate ligament reconstruction. Previously, little research was reported regarding whether the local application of rapamycin (RAPA) could reduce intraarticular adhesion following...
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titleReduction of intraarticular adhesion of knee by local application of rapamycin in rabbits via inhibition of fibroblast proliferation and collagen synthesis
authorZhao, Shuai ; Sun, Yu ; Li, Xiaolei ; Wang, Jingcheng ; Yan, Lianqi ; Chen, Hui ; Wang, Daxin ; Dai, Jihang ; He, Jun ; Zhao, Shuai ; Sun, Yu ; Li, Xiaolei ; Wang, Jingcheng ; Yan, Lianqi ; Chen, Hui ; Wang, Daxin ; Dai, Jihang ; He, Jun
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abstractBackground The formation of intraarticular adhesion is a common complication after total knee arthroplasty or anterior cruciate ligament reconstruction. Previously, little research was reported regarding whether the local application of rapamycin (RAPA) could reduce intraarticular adhesion following...
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